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pro vyhledávání: '"Perczel, A"'
Autor:
Keresztes, Laszlo, Szogi, Evelin, Varga, Balint, Farkas, Viktor, Perczel, Andras, Grolmusz, Vince
Hexapeptides are increasingly applied as model systems for studying the amyloidogenecity properties of oligo- and polypeptides. It is possible to construct 64 million different hexapeptides from the twenty proteinogenic amino acid residues. Today's e
Externí odkaz:
http://arxiv.org/abs/2309.03624
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Aggregation-prone-motifs (APRs) of proteins are short segments, which – as isolated peptides - form diverse amyloid-like crystals. We introduce two APRs - designed variants of the incretin mimetic Exendin-4 - that both display crystal-phas
Externí odkaz:
https://doaj.org/article/f88d5d33f81b4ec39acf674e4aa1f77d
Autor:
Péter Ábrányi-Balogh, Dávid Bajusz, Zoltán Orgován, Aaron B. Keeley, László Petri, Nikolett Péczka, Tibor Viktor Szalai, Gyula Pálfy, Márton Gadanecz, Emma K. Grant, Tímea Imre, Tamás Takács, Ivan Ranđelović, Marcell Baranyi, András Marton, Gitta Schlosser, Qirat F. Ashraf, Elvin D. de Araujo, Tamás Karancsi, László Buday, József Tóvári, András Perczel, Jacob T. Bush, György M. Keserű
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Fragment screening is a popular strategy of generating viable chemical starting points especially for challenging targets. Although fragments provide a better coverage of chemical space and they have typically higher chance of binding, their
Externí odkaz:
https://doaj.org/article/0a79f05dcd144d4ba343eaa1f806db99
Methods from artificial intelligence (AI), in general, and machine learning, in particular, have kept conquering new territories in numerous areas of science. Most of the applications of these techniques are restricted to the classification of large
Externí odkaz:
http://arxiv.org/abs/2210.11842
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Protein folds and the local environments they create can be compared using a variety of differently designed measures, such as the root mean squared deviation, the global distance test, the template modeling score or the local distance diffe
Externí odkaz:
https://doaj.org/article/ac31ebfbcad6426b8e0efc5eb662abd5
Autor:
István Perczel, Saranya Chandran
Publikováno v:
Entangled Religions - Interdisciplinary Journal for the Study of Religious Contact and Transfer, Vol 11, Iss 5 (2024)
The present study deals with an inscription on a granite stele in the township of Muttuchira, Kottayam District, Kerala, India. The inscription was written in Malayalam, in the ancient Dravidian vaṭṭeḻuttu script, in 1581. It commemorates the e
Externí odkaz:
https://doaj.org/article/66bf0d766bec436297afa66232763527
Autor:
Irina Horváthné Pató, Szilvia Kresznerits, Tamás Szekeres, Ágnes Zinner-Gérecz, Dóra Perczel-Forintos
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionThe behavioral addiction model posits that repetitive suicidal behaviors can serve as maladaptive strategies for managing stress and negative emotional states, akin to substance addiction. Both behaviors involve negative emotions, offer t
Externí odkaz:
https://doaj.org/article/ea110daadc664bd9980fef8eeca1d238
Publikováno v:
In Computers in Biology and Medicine September 2024 179
Autor:
Keresztes, Laszlo, Szogi, Evelin, Varga, Balint, Farkas, Viktor, Perczel, Andras, Grolmusz, Vince
Hexapeptides are widely applied as a model system for studying amyloid-forming properties of polypeptides, including proteins. Recently, large experimental databases have become publicly available with amyloidogenic labels. Using these datasets for t
Externí odkaz:
http://arxiv.org/abs/2202.14031
Autor:
D. Perczel-Forintos, D. Sal
Publikováno v:
European Psychiatry, Vol 67, Pp S50-S50 (2024)
Introduction Headache is a very common health problem worldwide and in our country due to the increasing environmental damage and daily stress. The proportion of patients with headache in general practice is 4-5%, in neurology up to 30%. Chronic head
Externí odkaz:
https://doaj.org/article/05e5d7bcee7047b4895519fb485bfd56