Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Percy F. Sumariwalla"'
Autor:
J Brian de Souza, Uduak Okomo, Neal D Alexander, Naveed Aziz, Benjamin M J Owens, Harparkash Kaur, Momodou Jasseh, Sant Muangnoicharoen, Percy F Sumariwalla, David C Warhurst, Stephen A Ward, David J Conway, Luis Ulloa, Kevin J Tracey, Brian M J Foxwell, Paul M Kaye, Michael Walther
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e9867 (2010)
Safe, cheap and effective adjunct therapies preventing the development of, or reducing the mortality from, severe malaria could have considerable and rapid public health impact. Oral activated charcoal (oAC) is a safe and well tolerated treatment for
Externí odkaz:
https://doaj.org/article/9aec678a30cc4eeeaaa65f992719810f
Autor:
Christeene G. Haj, Raphael Mechoulam, Lumir Hanus, Percy F. Sumariwalla, Natalya M. Kogan, Mark Feldmann, Ruth Gallily, Zhana Yektin
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 355:66-75
Cannabidiol (CBD) is a component of cannabis, which does not cause the typical marijuana-type effects, but has a high potential for use in several therapeutic areas. In contrast to Δ(9)-tetrahydrocannabinol (Δ(9)-THC), it binds very weakly to the C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75bc115d78a99e765330c7268e154147
https://doi.org/10.1124/jpet.115.226100
https://doi.org/10.1124/jpet.115.226100
Autor:
Marc Feldmann, H. Michael Shepard, Ewa M. Paleolog, Damian Crawford, Juan Zhang, Percy F. Sumariwalla, Pei Jin, Suzanne Phillips, Brett Jorgensen, Irene Ni
Publikováno v:
Arthritis Research & Therapy
Introduction Despite the advent of biological therapies for the treatment of rheumatoid arthritis, there is a compelling need to develop alternative therapeutic targets for nonresponders to existing treatments. Soluble receptors occur naturally in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f45c9c15fb41fdccb8c869c078d643
https://doi.org/10.1186/ar2447
https://doi.org/10.1186/ar2447
Autor:
Percy F. Sumariwalla, Marc Feldmann, Susanna Tchilibon, Raphael Mechoulam, Ester Fride, Ruth Gallily
Objective To explore the antiarthritic potential of a novel synthetic cannabinoid acid, Hebrew University–320 (HU-320), in the DBA/1 mouse model of arthritis, and to investigate in vitro antiinflammatory and immunosuppressive effects of HU-320 on m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506531a8e4a85c177d0caf18d74dc742
https://ora.ox.ac.uk/objects/uuid:018c4232-99f6-424a-b01e-471421dab9c9
https://ora.ox.ac.uk/objects/uuid:018c4232-99f6-424a-b01e-471421dab9c9
Publikováno v:
International Journal of Experimental Pathology. 86:267-278
Type II collagen-induced arthritis (CIA) is an animal model of rheumatoid arthritis that has been used extensively to address questions of disease pathogenesis and to validate novel therapeutic targets. Susceptibility to CIA is strongly associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::762a475c09ae036a2b0aa08cec54766f
https://doi.org/10.1111/j.0959-9673.2005.00443.x
https://doi.org/10.1111/j.0959-9673.2005.00443.x
Publikováno v:
Arthritis Research & Therapy
During rheumatoid arthritis there is enlargement and increased cellularity of the synovial lining of joints, before invasion by the synovium of the underlying cartilage and bone. This increased tissue mass requires a network of blood vessels to suppl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc7c25da231d14cf3de49f7e24f8632
http://europepmc.org/articles/PMC154428
http://europepmc.org/articles/PMC154428
Autor:
Henrik Agersø, Kay McNamee, Vibeke Westphal Stennicke, Marc Feldmann, John Trowsdale, Fiona E. McCann, Parisa Amjadi, Fionula M. Brennan, David Ahern, Chiwen Chang, Ditte Tornehave, Percy F. Sumariwalla, Claus Haase, Birgitte Ursø, Anna K. Andersson
Publikováno v:
Arthritis and rheumatism. 63(9)
Objective To assess the role of the activating receptor NKG2D in arthritis. Methods Levels of NKG2D and its ligands were determined by fluorescence-activated cell sorting, real-time polymerase chain reaction, and immunohistochemistry in rheumatoid ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b1db311ff1733f5c65e6b1cd9f840e
http://ora.ox.ac.uk/objects/uuid:119c08f9-6df9-4968-877b-cd991e4dc830
http://ora.ox.ac.uk/objects/uuid:119c08f9-6df9-4968-877b-cd991e4dc830
Autor:
Michael Shepard, Ewa M. Paleolog, Yvonne Raatz, Serafim Kiriakidis, Marc Feldmann, Nasser M Malik, Pei Jin, Percy F. Sumariwalla
Publikováno v:
Rheumatology (Oxford, England). 49(10)
Objectives To determine the function of the angiopoietin (Ang)-Tie ligand-receptor system, and to assess the effect of Tie1-751, a naturally occurring extracellular domain of the Tie1 receptor derived by alternative splicing, in an in vivo model of R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6917c5345fde04ed48c5184d98c6bd
https://pubmed.ncbi.nlm.nih.gov/20547659
https://pubmed.ncbi.nlm.nih.gov/20547659
Autor:
Marc Feldmann, Brian M. J. Foxwell, Christine D. Palmer, Percy F. Sumariwalla, Fionula M. Brennan, L. B. Pickford
Publikováno v:
Rheumatology (Oxford, England). 48(1)
OBJECTIVES: To evaluate the clinical efficacy of a novel synthetic peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist, CLX-090717, in several in vitro cell culture systems and murine CIA, an experimental model of RA. METHODS: Perip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc791fb83422fcca0a6822ddc858a4c2
http://ora.ox.ac.uk/objects/uuid:6e398c75-a816-4f9e-9cc6-0d280d85acab
http://ora.ox.ac.uk/objects/uuid:6e398c75-a816-4f9e-9cc6-0d280d85acab
SUMMARYWe investigated the therapeutic potential of P-selectin glycoprotein ligand (PSGL)-1 in established collagen-induced arthritis (CIA) in DBA/1 mice. PSGL-1 is the high-affinity specific ligand for P-selectin and is thus important in cell recrui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5f8acd20e34f60d49c83472fcd7171
https://europepmc.org/articles/PMC1808991/
https://europepmc.org/articles/PMC1808991/