Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Percy C.K. Tsang"'
Autor:
Stephanie S. Liu, Percy C.K. Tsang, Rebecca Ching-Yu Leung, Hextan Y.S. Ngan, Karen K. L. Chan, Annie N.Y. Cheung, Kelvin Y.K. Chan
Publikováno v:
Tumor Biology. 29:105-113
The prevalent genotypes of human papillomavirus (HPV) infection and the significance of HPV16 integration in cervical precancerous lesions and cancer of Chinese women were investigated.HPV genotyping and HPV16 integration status were studied on 100 n
Autor:
Stephanie S. Liu, K. F. Tam, Percy C.K. Tsang, Vws Liu, Annie N.Y. Cheung, Hextan Ys Ngan, Ann M.W. Yip
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 133:331-341
Promoter hypermethylation is a common phenomenon in neoplasm. The aims of this study were (a) to compare the methylation profiles in different types of ovarian tumors and (b) to determine the possible relationship between the methylation status and d
Autor:
T.Y. Ng, Vws Liu, Ann M.W. Yip, K. F. Tam, L.C. Wong, Percy C.K. Tsang, Hextan Ys Ngan, Hui-Juan Yang
Publikováno v:
International Journal of Gynecological Cancer. 14:903-910
Plasma human papillomavirus (HPV)-DNA level was measured to evaluate the clinical usefulness of circulating DNA for cervical cancer management. DNA extracted from pretreatment plasma of 50 cervical cancer patients and from serial longitudinal plasma
Autor:
Hextan Ys Ngan, Y Wang, Annie N.Y. Cheung, Kelvin Y.K. Chan, Hui-Juan Yang, Percy C.K. Tsang, Ui-Soon Khoo, Vws Liu
Publikováno v:
Gynecologic Oncology. 93:435-440
Objective . The aim of this study is to investigate the prevalence of promotor CpG island methylation of the death-associated protein kinase ( DAPK ), p16 , and O 6 -methylguanine-DNA methyltransferase ( MGMT ) genes in both tumor and plasma samples
Autor:
Percy C.K. Tsang, T.Y. Ng, Pui Man Chiu, Phillip Nagley, Vincent W.S. Liu, Hui-Juan Yang, Annie N.Y. Cheung, Y Wang, L.C. Wong, Hextan Y.S. Ngan
Publikováno v:
British Journal of Cancer
To investigate the occurrence of somatic mitochondrial DNA (mtDNA) mutations in human primary endometrial carcinomas, we sequenced the D-loop region, the 12S and 16S rRNA genes of mtDNA of cancer tissues and their matched normal controls. About 56% (
Publikováno v:
Gynecologic Oncology. 82:269-272
Objective. The aim of this study was to investigate the feasibility of using DNA in the circulation as a diagnostic tool for cervical cancer. Methods. We used PCR followed by Southern hybridization to detect human papillomavirus (HPV) DNA in serum sa
Publikováno v:
BMC Cancer
BMC Cancer, Vol 6, Iss 1, p 212 (2006)
BMC Cancer, Vol 6, Iss 1, p 212 (2006)
Background: Epigenetic gene silencing is one of the major causes of carcinogenesis. Its widespread occurrence in cancer genome could inactivate many cellular pathways including DNA repair, cell cycle control, apoptosis, cell adherence, and detoxifica
Publikováno v:
Journal of the Society for Gynecologic Investigation. 13(7)
Adenosine triphosphate cell inability assay (ATP-CVA) was used previously to evaluate chemotherapy in uterine cancer cell lines. In this study, we have performed the ATP-CVA on endometrial cancer patients to study the feasibility of using ATP-CVA in
Autor:
Yue Wang, Percy C.K. Tsang, Hextan Y.S. Ngan, Wei-Cheng Xue, Annie N.Y. Cheung, Vincent W.S. Liu
Publikováno v:
Gynecologic oncology. 98(1)
Objective. Microsatellite instability (MSI) is a frequent genetic event in the D-loop region (which controls mitochondrial DNA (mtDNA) replication) of mitochondrial genome of endometrial cancer. We therefore investigated the relationship between mtMS
Autor:
Percy C.K. Tsang, Ann M.W. Yip, Vincent W.S. Liu, T.Y. Ng, Hextan Y.S. Ngan, Annie N.Y. Cheung, Hui-Juan Yang
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 24(6)
We have previously demonstrated the presence of human papillomavirus (HPV) DNA in several gynecological cancers using conventional PCR. In the present study, to further understand the role of HPV in malignant transformation of these cancers, the infe