Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Percilene Fazolin Vegi"'
Autor:
Luis Fernando Quejada, Renata de Almeida, Percilene Fazolin Vegi, Maurício Silva dos Santos, Alice Maria Rolim Bernardino, Mauricio Afonso Vericimo, Robson Xavier Faria
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 5, Iss , Pp 100045- (2022)
Mycoses annually affect about 2 million individuals worldwide, especially in tropical countries. Candida spp., one of the main etiologic agents of these mycoses, and in particular Candida albicans has been the most isolated pathogen in patients with
Externí odkaz:
https://doaj.org/article/d005fad141754b17ab111139b5a24439
Autor:
Jéssica V. Faria, Helena Carla Castro, Maurício S. dos Santos, Paula Alvarez Abreu, Alice M. R. Bernardino, Rômulo Gabriel De Miranda de Paula Pinto, Daiane de Jesus Viegas, Luciana Terra, Percilene Fazolin Vegi
Publikováno v:
Letters in Organic Chemistry. 17:779-787
Serious fungal infections are increasing worldwide and have become a great concern in the medical field since antifungal drugs are restricted to a few drug classes. This work aims to evaluate the antifungal activity of a series of 5-amino-1-aryl-3-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c3e9c15accabc519e17120d8ff8293d
https://doi.org/10.2174/1570178617666200210105246
https://doi.org/10.2174/1570178617666200210105246
Autor:
Robson Q. Monteiro, Jéssica V. Faria, Percilene Fazolin Vegi, André Luiz Lourenço, Tatiana P. Dutra, Alice M. R. Bernardino, Carlos Rangel Rodrigues, Max Seidy Saito, Marcos Vinicius Santana, Helena Carla Castro, Maurício S. dos Santos, Plínio Cunha Sathler, Gustavo S. P. Pinto
Publikováno v:
Journal of the Brazilian Chemical Society.
This article reports a novel virtual screening algorithm seeking the rational identification of novel lead anticoagulants. Seven 5-(3-methyl-1-aryl-1H-pyrazol-4-yl)-1H-tetrazoles and seven novel 1-aryl-4-(4,5-dihydro-1H-imidazol-2-yl)-3-methyl-1H-pyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38073437b745f091fba2a701f9d8db59
https://doi.org/10.21577/0103-5053.20180150
https://doi.org/10.21577/0103-5053.20180150
Autor:
Maurício S. dos Santos, Ana Gabriella Carvalho Miguita, Alice M. R. Bernardino, Nubia Boechat, Jéssica V. Faria, Percilene Fazolin Vegi
Publikováno v:
Bioorganicmedicinal chemistry. 25(21)
The pyrazole nucleus is an aromatic azole heterocycle with two adjacent nitrogen atoms. Pyrazole derivatives have exhibited a broad spectrum of biological activities, and approved pyrazole-containing drugs include celecoxib, antipyrine, phenylbutazon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d936b0dca16c901c9bd0d3f6f7cf1372
https://pubmed.ncbi.nlm.nih.gov/28988624
https://pubmed.ncbi.nlm.nih.gov/28988624
Autor:
Carlos Rangel Rodrigues, Helena Carla Castro, Rafael Garrett, Percilene Fazolin Vegi, Paula Alvarez Abreu, Izabel C.P.P. Frugulhetti, Alice M. R. Bernardino, Ilídio F. Afonso, Claudio Cesar Cirne Santos, Francisco das Chagas Abreu da Silveira, Lucio Mendes Cabral, Dilvani Oliveira Santos, Luiz C. S. Pinheiro, Julio C. Borges, Alexandre Reis de Azevedo, Bruno Leal
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:8196-8204
Antibacterial resistance is a complex problem that contributes to health and economic losses worldwide. The Staphylococcus epidermidis is an important nosocomial pathogen that affects immunocompromised patients or those with indwelling devices. Curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284dbca54e38789a4a3ca3e66911bf54
https://doi.org/10.1016/j.bmc.2008.07.035
https://doi.org/10.1016/j.bmc.2008.07.035
Autor:
Alice M. R. Bernardino, Mauricio S. dos Santos, Jéssica V. Faria, Percilene Fazolin Vegi, Julio C. Borges
Publikováno v:
Tetrahedron Letters. 54(42):5748-5750
In this Letter, we described the synthesis of new 5-(5-amino-1-aryl-1H-pyrazole-4-yl)-1H-tetrazoles 2a–c from 5-amino-1-aryl-1H-pyrazole-4-carbonitriles 1a–c as well as the unexpected 1H-pyrazolo[3,4-d]pyrimidine derivatives 6a–c from 5-amino-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150190b12fbfa49b9e5ae0ad071cbf44
Autor:
Mauricio S. dos Santos, Julio C. Borges, Alice M. R. Bernardino, Percilene Fazolin Vegi, Jéssica V. Faria
Publikováno v:
ChemInform. 45
In this Letter, we described the synthesis of new 5-(5-amino-1-aryl-1H-pyrazole-4-yl)-1H-tetrazoles 2a–c from 5-amino-1-aryl-1H-pyrazole-4-carbonitriles 1a–c as well as the unexpected 1H-pyrazolo[3,4-d]pyrimidine derivatives 6a–c from 5-amino-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88c3d54f7f7733cddadfacf731303957
https://doi.org/10.1002/chin.201408188
https://doi.org/10.1002/chin.201408188
Autor:
Alice M. R. Bernardino, Viviane dos Santos Faiões, Leonor L. Leon, Percilene Fazolin Vegi, Eduardo Caio Torres-Santos, Marilene M. Canto-Cavalheiro, Maurício S. dos Santos
Publikováno v:
Chemical biologydrug design. 83(3)
In this research, a series of substituted 5-(5-amino-1-aryl-1H-pyrazol-4-yl)-1H-tetrazoles were synthesized and evaluated for in vitro antileishmanial activity. Among the derivatives, examined compounds 3b and 3l exhibited promising activity against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f528cb0cbb9009924f000acbd24f9d
https://pubmed.ncbi.nlm.nih.gov/24119090
https://pubmed.ncbi.nlm.nih.gov/24119090