Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Per-Olov Gunnarsson"'
Publikováno v:
Xenobiotica. 30:179-192
1. The metabolism of delmopinol, an inhibitor of plaque formation and gingivitis. has been studied after mouth rinsing or an oral dose of 14C-delmopinol to healthy male volunteers. The metabolite pattern was studied in urine and plasma samples (unhyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5825069cf4da2c8868052c4693caabfc
https://doi.org/10.1080/004982500237767
https://doi.org/10.1080/004982500237767
Publikováno v:
Biopharmaceutics & Drug Disposition. 21:53-67
The absorption and disposition of roquinimex (Linomide) were studied in four male and two female healthy volunteers. The subjects received a single oral aqueous solution of 14C-labelled roquinimex, about 0.1 mg/kg, after an overnight fast. Blood samp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0998ddef9f2a1b1ddc729cd027354c7c
https://doi.org/10.1002/1099-081x(200003)21:2<53::aid-bdd214>3.0.co
https://doi.org/10.1002/1099-081x(200003)21:2<53::aid-bdd214>3.0.co
Publikováno v:
Xenobiotica. 30:905-914
1. Roquinimex, a novel immunomodulator, is metabolized in liver microsomes from mouse and rat via cytochrome P450s to four hydroxylated and two demethylated metabolites (R1-6). The study investigated which cytochrome P450 enzyme(s) is responsible for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e959f02ed6b88ec49d563a0fc09eb9
https://doi.org/10.1080/004982500433327
https://doi.org/10.1080/004982500433327
Publikováno v:
Xenobiotica. 30:371-380
1. In vitro studies with roquinimex, an immuno-modulator, in liver microsomes from mouse and rat were conducted to evaluate the primary metabolism and compare the metabolite pattern as well as the rate of metabolism with the in vivo pharmacokinetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6137a5ab44b6b531f320654e0e1cdfc9
https://doi.org/10.1080/004982500237578
https://doi.org/10.1080/004982500237578
Publikováno v:
Xenobiotica. 29:783-792
1. The cytochrome P450 (CYP)-mediated metabolism of tauromustine has been evaluated in liver and lung microsomes from various species. Liver microsomes from rat pretreated with typical CYP inducers, human liver microsomes and cDNA-expressed human CYP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c09a11eb7bd2c542b20fd8c0cc119b
https://doi.org/10.1080/004982599238236
https://doi.org/10.1080/004982599238236
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 45:32-34
The stability of two nitrosoureas, tauromustine and lomustine, has been investigated in different media and buffers. All media tested, except Leibovitz's L-15 medium, significantly increased the degradation rate of the investigated nitrosoureas at pH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78f991d4f7a518aab95a72beebfcc71
https://doi.org/10.1007/s11626-008-9147-4
https://doi.org/10.1007/s11626-008-9147-4
Autor:
Per Antonsson, Jesper Olsson, Mikael Dohlsten, Robert Persson, Per-Olov Gunnarsson, Lennart Ohlsson, Terje Kalland, Thomas Brodin, Morten Soegaard, Anna Molander, Roland d'Argy
Publikováno v:
Advanced Drug Delivery Reviews. 31:131-142
Superantigens (SAgs) are a collection of bacterial and viral proteins with potent immunostimulatory properties. SAgs bind to Major Histocompatibility Complex Class II (MHC II) molecules of antigen presenting cells (APCs) and activate a high frequency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4acef52bb1568e122bfdb3f6f39e99d
https://doi.org/10.1016/s0169-409x(97)00097-5
https://doi.org/10.1016/s0169-409x(97)00097-5
Autor:
Mirtha Grande, Kjell Carlström, Per Olov Gunnarsson, Reinhard Stege, Åke Pousette, Peter Henriksson
Publikováno v:
The Prostate. 31:193-197
Background Treatment of prostatic disease with GnRH agonists or by orchidectomy affects bone mass negatively. Estrogen treatment has beneficial effects on bone mass in women and might hypothetically have a bone preserving capacity also in patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882c96679564d45595be61ca051bd364
https://doi.org/10.1002/(sici)1097-0045(19970515)31:3<193::aid-pros8>3.0.co
https://doi.org/10.1002/(sici)1097-0045(19970515)31:3<193::aid-pros8>3.0.co
Publikováno v:
Clinical Drug Investigation. 12:198-206
A nicotine transdermal delivery system (NTDS) designed to deliver 15 mg/16 hours (Nicotrol®) was applied to 40 healthy smoking volunteers in 3 separate studies: A single administration to different body sites, a multiple-dose study with 16-hour repe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2306b98fdb3d441b97753f9883ade7ad
https://doi.org/10.2165/00044011-199612040-00005
https://doi.org/10.2165/00044011-199612040-00005
Autor:
Emanuela Marinoni, S. Mashiach, Chieh-Yu Lin, Reinhard Neubert, Günther Schmidt, M. Shefi, Eran Hadas, Isabella Delgado, Chyong-Huey Lai, Ettore Cicinelli, C. Muttinelli, G. Rolfi, Sadao Yamashita, M. Sbracia, Arie Herman, Hiroji Okada, Helena Jernström, Yigal Soffer, Yasuko Fujimoto, Chia C. Pao, Ahmed Shafik, Y. Frenkel, Eliahu Caspi, S. Passi, Ömer Cobanoglu, Romolo di Iorio, Yohsuke Ohno, Ahmet Zeki Isik, Ornella de Pità, Per Olov Gunnarsson, Sven-Börje Andersson, Nicola Blasi, A. Lusky, Reuvit Halperin, Håkan Olsson, Chin-Yi Wang, E. Dolev, Maurizio Bresadola, Mitsuko Kawashima, Orjan Nordle, Flora Ippoliti, Pasquale Silvio Anastasio, M. Weiss, Mehmet Ali Vardar, M. Nicotra, Raphael Ron-El, Gürkan Zorlu, Kenichi Hosokawa, Refik Burgut, Esra Kuscu, Francesco Romano, Carlo Parisi, Carl-Johan Johansson, Turan Çetin, Yoshinobu Watanabe, Abraham Golan, Joachim W. Dudenhausen, Cansun Demir, Ian Bukovsky, Lale Kutluay, Kiyoko Koishi
Publikováno v:
Gynecologic and Obstetric Investigation. 38:I-IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c36ecca0d1fdfb79c29cebe5effa7772
https://doi.org/10.1159/000292483
https://doi.org/10.1159/000292483