Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Per-Olof Syrén"'
Autor:
David Hueting, Karen Schriever, Rui Sun, Stelios Vlachiotis, Fanglei Zuo, Likun Du, Helena Persson, Camilla Hofström, Mats Ohlin, Karin Walldén, Marcus Buggert, Lennart Hammarström, Harold Marcotte, Qiang Pan-Hammarström, Juni Andréll, Per-Olof Syrén
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract We report the application of ancestral sequence reconstruction on coronavirus spike protein, resulting in stable and highly soluble ancestral scaffold antigens (AnSAs). The AnSAs interact with plasma of patients recovered from COVID-19 but d
Externí odkaz:
https://doaj.org/article/7efece04ed6248b3af38175bd28035f3
Autor:
Emil Sporre, Jan Karlsen, Karen Schriever, Johannes Asplund-Samuelsson, Markus Janasch, Linnéa Strandberg, Anna Karlsson, David Kotol, Luise Zeckey, Ilaria Piazza, Per-Olof Syrén, Fredrik Edfors, Elton P. Hudson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Metabolite-level regulation of enzyme activity is important for microbes to cope with environmental shifts. Knowledge of such regulations can also guide strain engineering for biotechnology. Here we apply limited proteolysis-small molecule m
Externí odkaz:
https://doaj.org/article/2c6980d3398e4e32bbf83c4737c7e657
Autor:
Arne Stamm, Johannes Öhlin, Caroline Mosbech, Peter Olsén, Boyang Guo, Elisabeth Söderberg, Antonino Biundo, Linda Fogelström, Shubhankar Bhattacharyya, Uwe T. Bornscheuer, Eva Malmström, Per-Olof Syrén
Publikováno v:
JACS Au, Vol 1, Iss 11, Pp 1949-1960 (2021)
Externí odkaz:
https://doaj.org/article/5d17fc636e334cfdb511c23e9891b752
Autor:
Natalie M. Hendrikse, Anna Sandegren, Tommy Andersson, Jenny Blomqvist, Åsa Makower, Dominik Possner, Chao Su, Niklas Thalén, Agneta Tjernberg, Ulrica Westermark, Johan Rockberg, Stefan Svensson Gelius, Per-Olof Syrén, Erik Nordling
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102154- (2021)
Summary: We show the successful application of ancestral sequence reconstruction to enhance the activity of iduronate-2-sulfatase (IDS), thereby increasing its therapeutic potential for the treatment of Hunter syndrome—a lysosomal storage disease c
Externí odkaz:
https://doaj.org/article/d39df5cce7224dbcaf4d0e1329c50468
Autor:
Sepideh Zokaei, Renee Kroon, Johannes Gladisch, Bryan D. Paulsen, Wonil Sohn, Anna I. Hofmann, Gustav Persson, Arne Stamm, Per‐Olof Syrén, Eva Olsson, Jonathan Rivnay, Eleni Stavrinidou, Anja Lund, Christian Müller
Publikováno v:
Advanced Science, Vol 8, Iss 2, Pp n/a-n/a (2021)
Abstract Polar polythiophenes with oligoethylene glycol side chains are exceedingly soft materials. A low glass transition temperature and low degree of crystallinity prevents their use as a bulk material. The synthesis of a copolymer comprising 1) s
Externí odkaz:
https://doaj.org/article/efd7a19215a8448a861e9661f7c2d360
Publikováno v:
ACS Omega, Vol 2, Iss 11, Pp 8495-8506 (2017)
Externí odkaz:
https://doaj.org/article/54996684daf84308a61a6dc04a655576
Publikováno v:
Catalysts, Vol 6, Iss 6, p 90 (2016)
The discovery and generation of biocatalysts with extended catalytic versatilities are of immense relevance in both chemistry and biotechnology. An enhanced atomistic understanding of enzyme promiscuity, a mechanism through which living systems acqui
Externí odkaz:
https://doaj.org/article/09bf380e3f374d6bb36bc7e6c1f0d295
Autor:
Sathiyaraj Subramaniyan, Nasim Najjarzadeh, Sudarsana Reddy Vanga, Anna Liguori, Per-Olof Syrén, Minna Hakkarainen
Publikováno v:
ACS Sustainable Chemistry & Engineering. 11:3451-3465
Publikováno v:
The Journal of Physical Chemistry B. 126:3809-3821
Thermostability is the key to maintain the structural integrity and catalytic activity of enzymes in industrial biotechnological processes, such as terpene cyclase-mediated generation of medicines, chiral synthons, and fine chemicals. However, afford
Due to prolonged exposure, microplastic particles are found in human blood and other bodily fluids. Despite a lack of toxicity studies regarding microplastics, harmful effects for humans seem plausible and cannot be excluded. As small plastic particl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbde0cdb0a5d81c01336c96b15de3994
https://doi.org/10.21203/rs.3.rs-2679376/v1
https://doi.org/10.21203/rs.3.rs-2679376/v1