Structural Modifications and Biological Evaluations of Rift Valley Fever Virus Inhibitors Identified from Chemical Library Screening

Autor: Koushikul Islam, Marcus Carlsson, Per-Anders Enquist, Weixing Qian, Marko Marttila, Mårten Strand, Clas Ahlm, Magnus Evander

Publikováno v: ACS Omega, Vol 7, Iss 8, Pp 6854-6868 (2022)

Externí odkaz: https://doaj.org/article/335fc04f9e4c46ceb8978af430769506

Selective auxin agonists induce specific AUX/IAA protein degradation to modulate plant development

Autor: Małgorzata Łangowska, Thomas Vain, Alexandre Ismail, Stefan Kepinski, Mattias Thelander, Adeline Rigal, Martin Kieffer, Sara Raggi, Karin Ljung, Ondřej Novák, Sigurd Ramans Harborough, Qian Ma, Barbora Pařízková, Mark Estelle, Noel Ferro, Yi Zhang, Fredrik Almqvist, Siamsa M. Doyle, Deepak Kumar Barange, Laurens Pauwels, Per Anders Enquist, Stéphanie Robert, Judy Callis

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 13

Significance The plant hormone auxin coordinates almost all aspects of plant development. Throughout plant life, the expression of hundreds of genes involved in auxin regulation is orchestrated via several combinatorial and cell-specific auxin percep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c505202e3769275d39f6c2c8ef4468b
https://eprints.whiterose.ac.uk/143942/7/1809037116.full.pdf

Identification of a small molecule that stabilizes lipoprotein lipase in vitro and lowers triglycerides in vivo

Autor: Mikael Elofsson, Per-Anders Enquist, Madelene Ericsson, Stefan K. Nilsson, Rémi Caraballo, Gunilla Olivecrona, Aivar Lookene, Mikael Larsson

Publikováno v: Biochemical and Biophysical Research Communications. 450:1063-1069

Patients at increased cardiovascular risk commonly display high levels of plasma triglycerides (TGs), elevated LDL cholesterol, small dense LDL particles and low levels of HDL-cholesterol. Many remain at high risk even after successful statin therapy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c9fc9fc6c879cec1acf6b70ab3700c
https://doi.org/10.1016/j.bbrc.2014.06.114

Efficient Palladium(II) Catalysis under Air. Base-Free Oxidative Heck Reactions at Room Temperature or with Microwave Heating

Autor: Peter Nilsson, Mats Larhed, Per-Anders Enquist, Aake Pilotti, Jonas Lindh

Publikováno v: The Journal of Organic Chemistry. 72:7957-7962

Scope and limitations of the base-free oxidative Heck reaction with arylboronic acids have been explored. Under our conditions, the dmphen-palladium(II)-catalyzed arylation proceeded with air or p-benzoquinone as reoxidants of palladium(0). We found

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474752fd892b738097482a925d6d9588
https://doi.org/10.1021/jo701434s

ESI-MS Detection of Proposed Reaction Intermediates in the Air-Promoted and Ligand-Modulated Oxidative Heck Reaction

Autor: Peter M. Nilsson, Mats Larhed, Per-Anders Enquist, Per J. R. Sjöberg

Publikováno v: The Journal of Organic Chemistry. 71:8779-8786

Electrospray ionization mass spectrometry (ESI-MS) and subsequent MS/MS analyses were used to directly detect palladium-containing cationic reaction intermediates in a ligand controlled palladium(II)-catalyzed oxidative Heck arylation. All potential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49e4e39c51360b8dd70513c3da47978
https://doi.org/10.1021/jo061437d