Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Per Olaf Ekstrøm"'
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-8 (2023)
Abstract Objective Tumors are heterogeneous three-dimensional masses populated by numerous cell types, including distinct sub-clones of cancerous cells. Various sub-clones within the same tumor mass may respond differently to cancer treatment, and in
Externí odkaz:
https://doaj.org/article/176a176885cb4c47a1de5292eb97ff36
Autor:
Christian Arstad, Kristin Taskén, Paulo Refinetti, Ulrika Axcrona, Karl-Erik Giercksky, Per Olaf Ekstrøm
Publikováno v:
Prostate Cancer, Vol 2020 (2020)
Primary prostate tumor heterogeneity is poorly understood, leaving research efforts with challenges regarding the initiation and advancement of the disease. The growth of tumor cells is accompanied by mutations in nuclear and in mitochondrial genomes
Externí odkaz:
https://doaj.org/article/9f4a8f1a6ad44f27a4f77960cdfdbae0
Autor:
Mev Dominguez-Valentin, Sigve Nakken, Hélène Tubeuf, Daniel Vodak, Per Olaf Ekstrøm, Anke M. Nissen, Monika Morak, Elke Holinski-Feder, Alexandra Martins, Pål Møller, Eivind Hovig
Publikováno v:
BMC Medical Genetics, Vol 19, Iss 1, Pp 1-19 (2018)
Abstract Background The genetic mechanisms for families who meet the clinical criteria for Lynch syndrome (LS) but do not carry pathogenic variants in the mismatch repair (MMR) genes are still undetermined. We aimed to study the potential contributio
Externí odkaz:
https://doaj.org/article/a471ced28e4c4bb7ac5c073ec240e25d
Autor:
Mev Dominguez-Valentin, D. Gareth R. Evans, Sigve Nakken, Hélène Tubeuf, Daniel Vodak, Per Olaf Ekstrøm, Anke M. Nissen, Monika Morak, Elke Holinski-Feder, Alexandra Martins, Pål Møller, Eivind Hovig
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 16, Iss 1, Pp 1-14 (2018)
Abstract Background In kindreds carrying path_BRCA1/2 variants, some women in these families will develop cancer despite testing negative for the family’s pathogenic variant. These families may have additional genetic variants, which not only may i
Externí odkaz:
https://doaj.org/article/6deea8d410b04800addd158ba179a27c
Autor:
Christian Arstad, Paulo Refinetti, Annette Torgunrud Kristensen, Karl-Erik Giercksky, Per Olaf Ekstrøm
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background The prognostic significance of free cancer cells detected in peritoneal fluid at the time of rectal surgery remains unclear. A substantial number of patients will develop metastatic disease even with successful local treatment. Th
Externí odkaz:
https://doaj.org/article/1968831076e44f8280aed798bfe9648d
Autor:
Elizabeth Zavaleta, Nelly Solis, Maria Isabel Palacios, Liz Elva Zevallos-Escobar, Edison Vasquez Corales, Juan Carlos Bazo-Alvarez, Constantino Dominguez-Barrera, Anthony Campos, Patrik Wernhoff, Per Olaf Ekstrøm, Pål Møller, Tina Visnovska, Eivind Hovig, Janina Balazar-Palacios, Karin Alvarez-Valenzuela, Sigve Nakken, Mev Dominguez-Valentin
Publikováno v:
Cancers; Volume 14; Issue 22; Pages: 5603
Background: Genetic testing for hereditary cancers is inconsistently applied within the healthcare systems in Latin America. In Peru, the prevalence and spectrum of cancer-predisposing germline variants is thus poorly characterized. Purpose: To deter
Autor:
Fatemeh Kaveh, Sen Zhao, Per Olaf Ekstrøm, Eivind Hovig, Alfonso Urbanucci, Karen E. Knudsen, Marta D Switlyk, Oscar Lilleby, Sigve Nakken, Wolfgang Lilleby
Publikováno v:
Journal of Personalized Medicine
Journal of Personalized Medicine, Vol 11, Iss 330, p 330 (2021)
Journal of Personalized Medicine, Vol 11, Iss 330, p 330 (2021)
Guidelines for genetic testing have been established for multiple tumor types, frequently indicating the most confident molecularly targeted treatment options. However, considering the often-complex presentation of individual cancer patients, in addi
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology
Frontiers in Oncology
Background
Previous studies have shown the value in studying lineage tracing in slices of human tumors. However, a tumor is not a two-dimensional structure and to better understand how a tumor, and its corresponding metastasis grow, a three-dime
Previous studies have shown the value in studying lineage tracing in slices of human tumors. However, a tumor is not a two-dimensional structure and to better understand how a tumor, and its corresponding metastasis grow, a three-dime
Autor:
Eivind Hovig, Hélène Tubeuf, Sigve Nakken, Mev Dominguez-Valentin, Gabriel Capellá, Elke Holinski-Feder, D. Gareth Evans, Anke M. Nissen, Ben Davidson, Arild Holth, Alexandra Martins, Per Olaf Ekstrøm, Pål Møller, Monika Morak, Daniel Vodak
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Dipòsit Digital de la UB
Universidad de Barcelona
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Dipòsit Digital de la UB
Universidad de Barcelona
We have surveyed 191 prospectively sampled familial cancer patients with no previously detected pathogenic variant in the BRCA1/2, PTEN, TP53 or DNA mismatch repair genes. In all, 138 breast cancer (BC) cases, 34 colorectal cancer (CRC) and 19 multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6cfda2d970d357a0ce9ccc7538736f8
http://hdl.handle.net/2445/168019
http://hdl.handle.net/2445/168019
Autor:
Eivind Hovig, D. Gareth Evans, Per Olaf Ekstrøm, Pål Møller, Hélène Tubeuf, Alexandra Martins, Elke Holinski-Feder, Monika Morak, Sigve Nakken, Daniel Vodak, Mev Dominguez-Valentin, Anke M. Nissen
Publikováno v:
Hereditary Cancer in Clinical Practice
Hereditary Cancer in Clinical Practice, BioMed Central, 2018, 16 (1), ⟨10.1186/s13053-018-0086-0⟩
Hereditary Cancer in Clinical Practice, Vol 16, Iss 1, Pp 1-14 (2018)
Dominguez Valentin, M, Evans, D G, Nakken, S, Tubeuf, H, Vodak, D, Ekstrøm, P O, Nissen, A M, Morak, M, Holinski-Feder, E, Martins, A, Møller, P & Hovig, E 2018, ' Genetic variants of prospectively demonstrated phenocopies in BRCA1/2 kindreds ', Hereditary cancer in clinical practice, vol. 16, no. 4 . https://doi.org/10.1186/s13053-018-0086-0
Hereditary Cancer in Clinical Practice, BioMed Central, 2018, 16 (1), ⟨10.1186/s13053-018-0086-0⟩
Hereditary Cancer in Clinical Practice, Vol 16, Iss 1, Pp 1-14 (2018)
Dominguez Valentin, M, Evans, D G, Nakken, S, Tubeuf, H, Vodak, D, Ekstrøm, P O, Nissen, A M, Morak, M, Holinski-Feder, E, Martins, A, Møller, P & Hovig, E 2018, ' Genetic variants of prospectively demonstrated phenocopies in BRCA1/2 kindreds ', Hereditary cancer in clinical practice, vol. 16, no. 4 . https://doi.org/10.1186/s13053-018-0086-0
Background In kindreds carrying path_BRCA1/2 variants, some women in these families will develop cancer despite testing negative for the family’s pathogenic variant. These families may have additional genetic variants, which not only may increase t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3dec5419bbd493ad79813796ffd443
https://hal-normandie-univ.archives-ouvertes.fr/hal-02336104
https://hal-normandie-univ.archives-ouvertes.fr/hal-02336104