Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Per Niklas Hedde"'
Autor:
Brian T. Le, Katherine M. Auer, David A. Lopez, Justin P. Shum, Brian Suarsana, Ga-Young Kelly Suh, Per Niklas Hedde, Siavash Ahrar
Publikováno v:
HardwareX, Vol 18, Iss , Pp e00533- (2024)
Microscopes are essential for the biomechanical and hydrodynamical investigation of small aquatic organisms. We report a prototype of a do-it-yourself microscope that enables the visualization of organisms from two orthogonal imaging planes — top a
Externí odkaz:
https://doaj.org/article/9d2eee8a875346d9bc152775889001b6
Autor:
Aude I. Segaliny, Jayapriya Jayaraman, Xiaoming Chen, Jonathan Chong, Ryan Luxon, Audrey Fung, Qiwei Fu, Xianzhi Jiang, Rodrigo Rivera, Xiaoya Ma, Ci Ren, Jan Zimak, Per Niklas Hedde, Yonglei Shang, George Wu, Weian Zhao
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
A single-cell based bispecific antibody (BsAb) discovery pipeline, based on a microfluidics droplets generation and sorting systems, has the potential to speed up the discovery and development of functional antibodies such as BsAb therapeutics.
Externí odkaz:
https://doaj.org/article/7a14b50910074c84bb0bfc0a503c1bb8
Autor:
Tam Vu, Alexander Vallmitjana, Joshua Gu, Kieu La, Qi Xu, Jesus Flores, Jan Zimak, Jessica Shiu, Linzi Hosohama, Jie Wu, Christopher Douglas, Marian L. Waterman, Anand Ganesan, Per Niklas Hedde, Enrico Gratton, Weian Zhao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Spatial-omics methods with ease-of-use and high multiplexing are in demand. Here the authors report Multi Omic Single-scan Assay with Integrated Combinatorial Analysis (MOSAICA) which uses Spectral and Fluorescence Lifetime Imaging and Microscopy; th
Externí odkaz:
https://doaj.org/article/3a42cb1c065c4f01927be67c3c3c58b9
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Hedde et al. demonstrate the use of ultrafast phasor-based hyperspectral snapshot microscopy for biomedical imaging. This technique can improve imaging speed by 10-100 fold and enables 3D hyperspectral imaging of live tissues without using expensive
Externí odkaz:
https://doaj.org/article/364263388e1947e280262452f6f149c7
Autor:
Barbara Barylko, Per Niklas Hedde, Clinton A. Taylor, Derk D. Binns, Yu-Kai Huang, Gemma Molinaro, Kimberly M. Huber, David M. Jameson, Joseph P. Albanesi
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2022)
Calmodulin kinase-like vesicle-associated (CaMKv), a pseudokinase belonging to the Ca2+/calmodulin-dependent kinase family, is expressed predominantly in brain and neural tissue. It may function in synaptic strengthening during spatial learning by pr
Externí odkaz:
https://doaj.org/article/1eee19e0d09e4ea59c6565c1b7dfec03
Publikováno v:
Biology, Vol 12, Iss 1, p 116 (2023)
Selective plane illumination microscopy (SPIM), or light sheet microscopy, is a powerful imaging approach. However, access to and interfacing microscopes with microfluidics have remained challenging. Complex interfacing with microfluidics has limited
Externí odkaz:
https://doaj.org/article/d667f4ea38b74d99aa2e3c66b836e870
Autor:
Tara C. Tassin, Barbara Barylko, Per Niklas Hedde, Yan Chen, Derk D. Binns, Nicholas G. James, Joachim D. Mueller, David M. Jameson, Ronald Taussig, Joseph P. Albanesi
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Mutations in the gene encoding dynamin 2 (DNM2), a GTPase that catalyzes membrane constriction and fission, are associated with two autosomal-dominant motor disorders, Charcot-Marie-Tooth disease (CMT) and centronuclear myopathy (CNM), which affect n
Externí odkaz:
https://doaj.org/article/6e438375a0ef4ebcb44d832afd6dab34
Autor:
Sungjun Beck, Rie Nakajima, Algis Jasinskas, Timothy J. Abram, Sun Jin Kim, Nader Bigdeli, Delia F. Tifrea, Jenny Hernandez-Davies, D. Huw Davies, Per Niklas Hedde, Philip L. Felgner, Weian Zhao
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2238 (2022)
High-throughput and rapid screening testing is highly desirable to effectively combat the rapidly evolving COVID-19 pandemic co-presents with influenza and seasonal common cold epidemics. Here, we present a general workflow for iterative development
Externí odkaz:
https://doaj.org/article/23012589569b4c5d8fcec8a9f9ae2c26
Autor:
Azusa Kobayashi, Ayaka Ito, Ibuki Shirakawa, Atsushi Tamura, Susumu Tomono, Hideo Shindou, Per Niklas Hedde, Miyako Tanaka, Naotake Tsuboi, Takuji Ishimoto, Sachiko Akashi-Takamura, Shoichi Maruyama, Takayoshi Suganami
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Accumulating evidence suggests that cholesterol accumulation in leukocytes is causally associated with the development of autoimmune diseases. However, the mechanism by which fatty acid composition influences autoimmune responses remains unclear. To
Externí odkaz:
https://doaj.org/article/15704b94f80744bbb9fe0cc111083c27
Autor:
Per Niklas Hedde, Leonel Malacrida, Barbara Barylko, Derk D. Binns, Joseph P. Albanesi, David M. Jameson
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
The activity-regulated cytoskeletal-associated protein (Arc, also known as Arg3.1) is an immediate early gene product induced by activity/experience and required for multiple modes of synaptic plasticity. Both long-term potentiation (LTP) and long-te
Externí odkaz:
https://doaj.org/article/a082cad906e842259d93da095f20b0d1