Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Per M. Åberg"'
Autor:
Guanghui Liu, Catherine Betts, Danen M. Cunoosamy, Per M. Åberg, Jorrit J. Hornberg, Kinga Balogh Sivars, Taylor S. Cohen
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Animal models remain invaluable for study of respiratory diseases, however, translation of data generated in genetically homogeneous animals housed in a clean and well-controlled environment does not necessarily provide insight to the human
Externí odkaz:
https://doaj.org/article/a9cf2c514e3449689fd595ad4b0b503b
Autor:
Taylor S. Cohen, Kinga Balogh Sivars, Jorrit J. Hornberg, Catherine J. Betts, Guanghui Liu, Per M. Åberg, Danen Cunoosamy
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-14 (2019)
Respiratory Research
Respiratory Research
Animal models remain invaluable for study of respiratory diseases, however, translation of data generated in genetically homogeneous animals housed in a clean and well-controlled environment does not necessarily provide insight to the human disease s
Autor:
Anna Ollerstam, Kinga Balogh Sivars, Catherine J. Betts, Linnea Särén, Guanghui Liu, Xiao-Hong Zhou, Helena Douglasson, Per M. Åberg
Publikováno v:
Archives of toxicology. 95(8)
Chronic inflammatory diseases of the respiratory tract, such as chronic obstructive pulmonary disease (COPD) and asthma, are severe lung diseases that require effective treatments. In search for new medicines for these diseases, there is an unmet nee
Autor:
Ismo K. Koponen, Rebecca Fransson, Jorid B. Sørli, Yi Y. Zuo, Emilie Da Silva, Karin Sørig Hougaard, Kinga Balogh Sivars, Ingrid E.K. Weydahl, Per M. Åberg
Publikováno v:
Sorli, J B, Sivars, K B, Da Silva, E, Hougaard, K S, Koponen, I K, Zuo, Y Y, Weydahl, I E K, Aberg, P M & Fransson, R 2018, ' Bile salt enhancers for inhalation : Correlation between in vitro and in vivo lung effects ', International Journal of Pharmaceutics, vol. 550, no. 1-2, pp. 114-122 . https://doi.org/10.1016/j.ijpharm.2018.08.031
Sørli, J B, Sivars, K B, Da Silva, E, Hougaard, K S, Koponen, I K, Zuo, Y Y, Weydahl, I E K, Åberg, P M & Fransson, R 2018, ' Bile salt enhancers for inhalation: correlation between in vitro and in vivo lung effects ', International Journal of Pharmaceutics, vol. 550, no. 1-2, pp. 114-122 . https://doi.org/10.1016/j.ijpharm.2018.08.031
Sørli, J B, Sivars, K B, Da Silva, E, Hougaard, K S, Koponen, I K, Zuo, Y Y, Weydahl, I E K, Åberg, P M & Fransson, R 2018, ' Bile salt enhancers for inhalation: correlation between in vitro and in vivo lung effects ', International Journal of Pharmaceutics, vol. 550, no. 1-2, pp. 114-122 . https://doi.org/10.1016/j.ijpharm.2018.08.031
The lungs have potential as a means of systemic drug delivery of macromolecules. Systemic delivery requires crossing of the air-blood barrier, however with molecular size-dependent limitations in lung absorption of large molecules. Systemic availabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e22df9b94f2ebe28f1bc62f2c7c522a
https://curis.ku.dk/ws/files/210973183/1_s2.0_S0378517318306045_main.pdf
https://curis.ku.dk/ws/files/210973183/1_s2.0_S0378517318306045_main.pdf
Autor:
Ulf Sivars, Samuel Constant, Hui Zhang, Song Huang, Kinga Balogh Sivars, Ellinor Hornberg, Catherine J. Betts, Lena Brändén, Rosy Bonfante, Ian Robinson, Per M. Åberg
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 162(1)
Respiratory tract toxicity represents a significant cause of attrition of inhaled drug candidates targeting respiratory diseases. One of the key issues to allow early detection of respiratory toxicities is the lack of reliable and predictive in vitro
Autor:
Ingrid Pontén, Michael R. O’Donovan, David J. Nicholls, Alan Young, Alaa Saad, Cecilia Diaz Pohl, Peter Mutch, Charlotta Fred, Per M. Åberg
Publikováno v:
Mutagenesis. 28(2)
AZD9708 is a new chemical entity with selective and longacting β2-agonistic properties currently being evaluated by AstraZeneca for potential use in treatment of respiratory diseases by the inhaled route. As part of the toxicological characterisatio
Autor:
Ellinor Hornberg, Catherine J. Betts, K. Balogh Sivars, Per M. Åberg, S. Mairpady Shambat, Mattias Svensson, Puran Chen
Publikováno v:
Toxicology Letters. 258:S141