Zobrazeno 1 - 10
of 362
pro vyhledávání: '"Per Karlsson"'
Autor:
Per Karlsson, Robin Strand, Joel Kullberg, Karl Michaëlsson, Håkan Ahlström, Lars Lind, Andrei Malinovschi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract A cardiopulmonary exercise test (CPET) is a test assessing an individual’s physiological response during exercise. Results may be affected by body composition, which is best evaluated through imaging techniques like magnetic resonance imag
Externí odkaz:
https://doaj.org/article/75a97e038de3444fa73a0317765d9601
Autor:
Peter Larsson, Maria Cristina De Rosa, Benedetta Righino, Maxim Olsson, Bogdan Iulius Florea, Eva Forssell-Aronsson, Anikó Kovács, Per Karlsson, Khalil Helou, Toshima Z. Parris
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Computational pharmacogenomics can potentially identify new indications for already approved drugs and pinpoint compounds with similar mechanism-of-action. Here, we used an integrated drug repositioning approach based on transcriptomics data
Externí odkaz:
https://doaj.org/article/1b44d542d84c498ebb49958dfa4cacc1
Autor:
Peter Larsson, Maxim Olsson, Sithumini Sarathchandra, Anna Fäldt Beding, Eva Forssell-Aronsson, Anikó Kovács, Per Karlsson, Khalil Helou, Toshima Z. Parris
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Repurposing of FDA-approved drugs is a quick and cost-effective alternative to de novo drug development. Here, we identify genes involved in bortezomib sensitivity, predict cancer types that may benefit from treatment with bortezomib, and ev
Externí odkaz:
https://doaj.org/article/cb8556dc4f164843a07201a962a40d0f
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background and purpose: Chemotherapy-induced peripheral neuropathy (CIPN) is a troublesome side effect in patients exposed to taxanes in the treatment of cancer and may affect quality of life dramatically. Here we assessed whether serum levels of neu
Externí odkaz:
https://doaj.org/article/c6dcdc6b8b424ded9478fe1b22a2ac1c
Publikováno v:
ERJ Open Research, Vol 10, Iss 3 (2024)
Background The cardiopulmonary exercise test (CPET) evaluates cardiopulmonary function. In light of the obesity epidemic, it is important to understand how body composition affects interpretation of CPET results. The aim of the present study was to a
Externí odkaz:
https://doaj.org/article/40fdb7bc176140e98165f8e40c180102
Autor:
Peter Larsson, Daniella Pettersson, Maxim Olsson, Sithumini Sarathchandra, Alexandra Abramsson, Henrik Zetterberg, Ella Ittner, Eva Forssell-Aronsson, Anikó Kovács, Per Karlsson, Khalil Helou, Toshima Z. Parris
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract Triple-negative breast cancer (TNBC) is associated with poor prognosis and limited treatment options due to the lack of important receptors (estrogen receptor [ER], progesterone receptor [PR], and human epidermal growth factor receptor 2 [HE
Externí odkaz:
https://doaj.org/article/e80a4b8167f54e5caf8924d9786d6e04
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background and purpose: Doses to the coronary arteries in breast cancer (BC) radiotherapy (RT) have been suggested to be a risk predictor of long-term cardiac toxicity after BC treatment. We investigated the dose–risk relationships between near max
Externí odkaz:
https://doaj.org/article/c854240685254b0eb270074ad018fcce
Autor:
Moa Egelberg, Tommaso De Marchi, Gyula Pekar, Lena Tran, Pär‐Ola Bendahl, Axel Stenmark Tullberg, Erik Holmberg, Per Karlsson, Marianne Farnebo, Fredrika Killander, Emma Nimeús
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2029-2040 (2023)
Downregulation of the DNA repair protein WD40‐encoding RNA antisense to p53 (WRAP53) has been associated with radiotherapy resistance and reduced cancer survival. The aim of this study was to evaluate WRAP53 protein and RNA levels as prognostic and
Externí odkaz:
https://doaj.org/article/9f6a87e3a0fc4942be09a021d9f6b9ed
Autor:
Slavica Janeva, Ellen Krabbe, Toshima Z. Parris, Salmir Nasic, Marie Sundquist, Per Karlsson, Riccardo A. Audisio, Roger Olofsson Bagge, Anikó Kovács
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-11 (2023)
Abstract Background When ipsilateral multifocal primary breast cancer (IMBC) is detected, standard routine is to evaluate the largest tumor with immunohistochemistry (IHC). As all foci are not routinely characterized, many patients may not receive op
Externí odkaz:
https://doaj.org/article/41153ac5c52c4a31bf5f1cb43f65d9f0
Autor:
Pär-Ola Bendahl, Erik Holmberg, Jana de Boniface, Dan Lundstedt, Per Karlsson, Sara Alkner, Ingvil Mjaaland, Lisa Ryden, Johan Vikstrom, Helena Sackey, Elinore Wieslander
Publikováno v:
BMJ Open, Vol 13, Iss 9 (2023)
Introduction Modern systemic treatment has reduced incidence of regional recurrences and improved survival in breast cancer (BC). It is thus questionable whether regional radiotherapy (RT) is still beneficial in patients with sentinel lymph node (SLN
Externí odkaz:
https://doaj.org/article/f679c73bc8444fd493e30b7f3c116ea8