Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Per K. Christensen"'
Autor:
Per K. Christensen, Michael D. Feher, Niels V. Hartvig, Lina S. Mørch, Lise Lotte N. Husemoen
Publikováno v:
Diabetes Therapy
Introduction Uncontrolled type 2 diabetes (T2D) is associated with an increased risk of micro- and macrovascular complications and mortality. The impact of basal insulins on the risks of mortality and cardiovascular mortality in people with T2D has n
Autor:
Andrew M. Herzenberg, Darren J. Kelly, Sih Min Tan, Robyn G Langham, Hans-Henrik Parving, Yuan Zhang, Andrew Advani, Renae M. Gow, Kerri Thai, Weier Qi, Carol A. Pollock, Alison J. Cox, Kim A. Connelly, Richard E. Gilbert, Per K. Christensen
Publikováno v:
Journal of the American Society of Nephrology. 20:730-741
Excessive reactive oxygen species play a key role in the pathogenesis of diabetic nephropathy, but to what extent these result from increased generation, impaired antioxidant systems, or both is incompletely understood. Here, we report the expression
Autor:
Frans Boomsma, Anders Jorsal, Hans-Henrik Parving, Per K. Christensen, K. J. Schjoedt, Peter Rossing
Publikováno v:
Schjoedt, K J, Christensen, P K, Jorsal, A, Boomsma, F, Rossing, P & Parving, H-H 2009, ' Autoregulation of glomerular filtration rate during spironolactone treatment in hypertensive patients with type 1 diabetes : a randomized crossover trial ', Nephrology, Dialysis, Transplantation, vol. 24, no. 11, pp. 3343-9 . https://doi.org/10.1093/ndt/gfp311
Nephrology Dialysis Transplantation, 24(11), 3343-3349. Oxford University Press
University of Copenhagen
Nephrology Dialysis Transplantation, 24(11), 3343-3349. Oxford University Press
University of Copenhagen
Background. Autoregulation of GFR, i.e. maintenance of relative constancy of GFR despite variations in mean arterial pressure (MAP) > 80 mmHg, is impaired in diabetic kidney disease; furthermore, some antihypertensive drugs may jeopardize autoregulat
Autor:
Hans-Henrik Parving, Peter Karl Jacobsen, Peter Hovind, Steen Andersen, Kasper Rossing, Peter Rossing, Per K. Christensen, Lise Tarnow
Publikováno v:
Seminars in Nephrology. 24:147-157
The activity of the renin-angiotensin-aldosterone system (RAAS) is elevated both in the circulation and in the renal tissue of diabetic and nondiabetic nephropathies. The increased RAAS activity plays an important role in the hemodynamic and nonhemod
Autor:
Hans-Henrik Parving, Steen Andersen, Per K. Christensen, Peter Hovind, Henrik Post Hansen, Kasper Rossing
Publikováno v:
Diabetes Care. 26:569-574
OBJECTIVE—Irbesartan was renoprotective independently of its blood pressure-lowering effect in the Irbesartan in Patients With Type 2 Diabetes and Microalbuminuria (IRMA2) study. However, blood pressure was evaluated by trough office blood pressure
Publikováno v:
Diabetes Care. 26:156-162
OBJECTIVE—Calcium-channel blockade impairs renal autoregulation in animals. Impaired renal autoregulation leads to transmission of the systemic blood pressure (BP) into the glomerulus, resulting in capillary hypertension. Information on the impact
Publikováno v:
Diabetes Care. 25:95-100
OBJECTIVE—Many patients with diabetic nephropathy (DN) have levels of albuminuria >1 g/day and blood pressure >135/85 mmHg, despite antihypertensive combination therapy, including recommended doses of ACE inhibitors, e.g., lisinopril/enalapril at 2
Publikováno v:
Nephrology Dialysis Transplantation. 16:2337-2347
Background. In type 2 diabetic patients without retinopathy the cause of albuminuria is heterogeneous and our knowledge of the relationship between kidney structure and function in these patients is limited. Therefore, a long-term study evaluating th
Autor:
A. Major-Pedersen, M. A. Gall, A. Sato, Per K. Christensen, Hans-Henrik Parving, J Kastrup, L. Breum, Peter Rossing, A. Pietersen
Publikováno v:
Capital Region of Denmark
Patients with non-insulin-dependent diabetes (NIDDM) are at independent risk of cardiovascular death. The reason is only partially understood. The aim of our study was therefore to evaluate the impact of corrected QT interval length (QTc) and QT disp
Publikováno v:
Kidney International. 52:1369-1374
Impaired autoregulation of GFR in hypertensive non-insulin dependent diabetic patients. We investigated the effect of acute lowering of blood pressure (BP) upon glomerular filtration rate (GFR) in hypertensive non-insulin-dependent diabetes mellitus