Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Per Jynge"'
Autor:
Jan Olof G. Karlsson, Per Jynge
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4347 (2024)
Platinum-containing chemotherapeutic drugs are efficacious in many forms of cancer but are dose-restricted by serious side effects, of which peripheral neuropathy induced by oxidative–nitrosative-stress-mediated chain reactions is most disturbing.
Externí odkaz:
https://doaj.org/article/2e179c5dcae74b8e9b44fd8b57de9128
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 608 (2023)
Disappointing results from the POLAR A and M phase III trials involving colorectal cancer patients on chemotherapy with FOLFOX6 in curative (A) and palliative (M) settings have been reported by the principal investigators and the sponsor (PledPharma
Externí odkaz:
https://doaj.org/article/47e28ed65789481e908ff8e5b4d28203
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1937 (2021)
On 2 July 2021, highly negative results were reported from the POLAR A and M phase III trials in patients with colorectal cancer, treated with an oxaliplatin-based regimen and co-treated with calmangafodipir (CaM; PledOx®; PledPharma AB/Egetis Thera
Externí odkaz:
https://doaj.org/article/ae85682f29224934b194bf9f1c96accf
Publikováno v:
Translational Oncology, Vol 10, Iss 4, Pp 641-649 (2017)
Oxaliplatin, in combination with 5-fluorouracil plus folinate (or capecitabine), has increased survival substantially in stage III colorectal cancer and prolonged life in stage IV patients, but its use is compromised because of severe toxicity. Chemo
Externí odkaz:
https://doaj.org/article/90bbdd6bca5a4f4188ca7c3bf07e665c
Publikováno v:
Antioxidants, Vol 9, Iss 10, p 971 (2020)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is characterized by massive inflammation of the arterial endothelium accompanied by vasoconstriction and widespread pulmonary micro thrombi. As a result, due to the destruction of nitric ox
Externí odkaz:
https://doaj.org/article/160b12882ad54a7fa2fab6c22ad66b73
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-2 (2019)
Externí odkaz:
https://doaj.org/article/82f92b5776c94136999cadb8bc4c029d
Publikováno v:
AJNR Am J Neuroradiol
BACKGROUND AND PURPOSE: The manganese ion is used as an intracellular MR imaging contrast agent to study neuronal function in animal models, but it remains unclear whether manganese-enhanced MR imaging can be similarly useful in humans. Using mangafo
Publikováno v:
Trials
Trials, Vol 20, Iss 1, Pp 1-2 (2019)
Trials, Vol 20, Iss 1, Pp 1-2 (2019)
Paracetamol (acetaminophen) overdose (POD) is the commonest cause of acute liver failure in Europe and North America. Current treatment involves the use of the antidote N-acetylcysteine (NAC) in patients deemed at risk of liver damage. This regimen w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c19943a86b78f7e93c4c43c24a01069
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-158968
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-158968
Autor:
Per Jynge, Jan Olof G. Karlsson
Publikováno v:
Acta Oncologica. 57:862-864
Acta Oncologica recently published an original article titled ‘Persistent prevention of oxaliplatin-induced peripheral neuropathy using calmangafodipir (PledOx®): a placebo-controlled randomized ph...
Publikováno v:
Antioxidants
Antioxidants, Vol 9, Iss 971, p 971 (2020)
Antioxidants, Vol 9, Iss 971, p 971 (2020)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is characterized by massive inflammation of the arterial endothelium accompanied by vasoconstriction and widespread pulmonary micro thrombi. As a result, due to the destruction of nitric ox