Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Per J. Klasse"'
Autor:
Anna-Janina Behrens, Snezana Vasiljevic, Laura K. Pritchard, David J. Harvey, Rajinder S. Andev, Stefanie A. Krumm, Weston B. Struwe, Albert Cupo, Abhinav Kumar, Nicole Zitzmann, Gemma E. Seabright, Holger B. Kramer, Daniel I.R. Spencer, Louise Royle, Jeong Hyun Lee, Per J. Klasse, Dennis R. Burton, Ian A. Wilson, Andrew B. Ward, Rogier W. Sanders, John P. Moore, Katie J. Doores, Max Crispin
Publikováno v:
Cell Reports, Vol 14, Iss 11, Pp 2695-2706 (2016)
The HIV-1 envelope glycoprotein trimer is covered by an array of N-linked glycans that shield it from immune surveillance. The high density of glycans on the trimer surface imposes steric constraints limiting the actions of glycan-processing enzymes,
Externí odkaz:
https://doaj.org/article/e2e8bb16346745dfaa8a226260faf0dc
Autor:
Silvia Capucci, Edmund G Wee, Torben Schiffner, Celia C LaBranche, Nicola Borthwick, Albert Cupo, Jonathan Dodd, Hansi Dean, Quentin Sattentau, David Montefiori, Per J Klasse, Rogier W Sanders, John P Moore, Tomáš Hanke
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0293148 (2023)
[This corrects the article DOI: 10.1371/journal.pone.0181886.].
Externí odkaz:
https://doaj.org/article/9afb22a50abb493ea347796b71174785
Autor:
Silvia Capucci, Edmund G Wee, Torben Schiffner, Celia C LaBranche, Nicola Borthwick, Albert Cupo, Jonathan Dodd, Hansi Dean, Quentin Sattentau, David Montefiori, Per J Klasse, Rogier W Sanders, John P Moore, Tomáš Hanke
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0181886 (2017)
Rabbits and monkeys immunized with HIV type 1 (HIV-1) native-like BG505 SOSIP.664 (BG505s) glycoprotein trimers are known to induce antibodies that can neutralize the autologous tier-2 virus. Here, we assessed the induction of HIV-1 trimer binding an
Externí odkaz:
https://doaj.org/article/96b2207bc5b24d9496ecdec92ae9f12b
Autor:
Antu K, Dey, Albert, Cupo, Gabriel, Ozorowski, Vaneet K, Sharma, Anna-Janina, Behrens, Eden P, Go, Thomas J, Ketas, Anila, Yasmeen, Per J, Klasse, Eddy, Sayeed, Heather, Desaire, Max, Crispin, Ian A, Wilson, Rogier W, Sanders, Thomas, Hassell, Andrew B, Ward, John P, Moore
Publikováno v:
Biotechnology and Bioengineering
We describe the properties of BG505 SOSIP.664 HIV‐1 envelope glycoprotein trimers produced under current Good Manufacturing Practice (cGMP) conditions. These proteins are the first of a new generation of native‐like trimers that are the basis for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::394825dcb4b255574d620a19a613e9bb
https://pubmed.ncbi.nlm.nih.gov/29150937
https://pubmed.ncbi.nlm.nih.gov/29150937
Publikováno v:
PLoS Pathogens, Vol 5, Iss 8, p e1000548 (2009)
HIV-1 variants resistant to small molecule CCR5 inhibitors recognize the inhibitor-CCR5 complex, while also interacting with free CCR5. The most common genetic route to resistance involves sequence changes in the gp120 V3 region, a pathway followed w
Externí odkaz:
https://doaj.org/article/b1a325f319c94c629d36884662e67e17