Inhibition of p53-dependent, but not p53-independent, cell death by U19 protein from human herpesvirus 6B.

Autor: Emil Kofod-Olsen, Janni M L Møller, Mariane H Schleimann, Bettina Bundgaard, Rasmus O Bak, Bodil Øster, Jacob G Mikkelsen, Ted Hupp, Per Höllsberg

Publikováno v: PLoS ONE, Vol 8, Iss 3, p e59223 (2013)

Infection with human herpesvirus (HHV)-6B alters cell cycle progression and stabilizes tumor suppressor protein p53. In this study, we have analyzed the activity of p53 after stimulation with p53-dependent and -independent DNA damaging agents during

Externí odkaz: https://doaj.org/article/47cab761a6914845b4a9830b3b2071cd

Epstein-Barr virus peptide presented by HLA-E is predominantly recognized by CD8(bright) cells in multiple sclerosis patients.

Autor: Pernille B Jørgensen, Astrid H Livbjerg, Hans J Hansen, Thor Petersen, Per Höllsberg

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e46120 (2012)

Multiple sclerosis (MS) is associated with Epstein-Barr virus (EBV) infection, but impaired immune suppression may be part of the disease pathogenesis. CD8(+) T cells that are restricted by HLA-E exert an important immunoregulatory mechanism. To expl

Externí odkaz: https://doaj.org/article/729f08fb4cdc45df93a3a3a2159a292c

Identification of multiple HPV types on spermatozoa from human sperm donors.

Autor: Maja D Kaspersen, Peter B Larsen, Hans Jakob Ingerslev, Jens Fedder, Gert Bruun Petersen, Jesper Bonde, Per Höllsberg

Publikováno v: PLoS ONE, Vol 6, Iss 3, p e18095 (2011)

Human papillomaviruses (HPV) may cause sexually transmitted disease. High-risk types of HPV are involved in the development of cervical cell dysplasia, whereas low-risk types may cause genital condyloma. Despite the association between HPV and cancer

Externí odkaz: https://doaj.org/article/f1d46086a64e4ef3adb858808b976264

Novel homozygous CD46 variant with C‐isoform expression affects C3b inactivation in atypical hemolytic uremic syndrome

Autor: Vivien R. Schack, Morten K. Herlin, Henrik Pedersen, J. Magnus Bernth Jensen, Mia Færch, Bettina Bundgaard, Rasmus K. Jensen, Uffe B. Jensen, Rikke Christensen, Gregers R. Andersen, Steffen Thiel, Per Höllsberg

Publikováno v: Schack, V R, Herlin, M K, Pedersen, H, Jensen, J M B, Faerch, M, Bundgaard, B, Jensen, R K, Jensen, U B, Christensen, R, Andersen, G R, Thiel, S & Höllsberg, P 2022, ' Novel homozygous CD46 variant with C-isoform expression affects C3b inactivation in atypical hemolytic uremic syndrome ', European Journal of Immunology, vol. 52, no. 10, pp. 1610-1619 . https://doi.org/10.1002/eji.202249838

Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy that may lead to organ failure. Dysregulation of the complement system can cause aHUS, and various disease-related variants in the complement regulatory protein CD46 are descri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0955c70b7024967005b4f960aee77931
https://doi.org/10.1002/eji.202249838

Expression of soluble CD83 in plasma from early-stage rheumatoid arthritis patients is not modified by anti-TNF-α therapy

Autor: Mikkel Østergaard, Kim Hørslev-Petersen, Peter Junker, Malene Hvid, Bent Deleuran, Anne Mette Fisker Kristensen, Kristian Stengaard-Pedersen, Merete Lund Hetland, Per Höllsberg

Publikováno v: Kristensen, A-M, Stengaard-Pedersen, K, Hetland, M L, Horsley-Petersen, K, Junker, P, Ostergaard, M, Hollsberg, P, Deleuran, B & Hvid, M 2017, ' Expression of soluble CD83 in plasma from early-stage rheumatoid arthritis patients is not modified by anti-TNF-alpha therapy ', Cytokine, vol. 96, pp. 1-7 . https://doi.org/10.1016/j.cyto.2017.02.017
Kristensen, A M F, Stengaard-Pedersen, K, Hetland, M L, Hørslev-Petersen, K, Junker, P, Østergaard, M, Höllsberg, P, Deleuran, B & Hvid, M 2017, ' Expression of soluble CD83 in plasma from early-stage rheumatoid arthritis patients is not modified by anti-TNF-α therapy ', Cytokine, vol. 96, pp. 1-7 . https://doi.org/10.1016/j.cyto.2017.02.017

Rheumatoid arthritis (RA) is an autoimmune disease which may lead to severe disabilities due to structural joint damage and extraarticular manifestations The dendritic cell marker CD83 belongs to the immunoglobulin superfamily and has previously been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9b33044278715c8e3717d513450af0
https://doi.org/10.1016/j.cyto.2017.02.017