Výsledky vyhledávání - "Per Brunmark"

Drug Absorption from the Isolated Perfused Rat Lung–Correlations with Drug Physicochemical Properties and Epithelial Permeability

Autor: Per Brunmark, Bo Nordén, Hans Lennernäs, Ann-Britt Jeppsson, Elisabeth Nilsson, Ursula Hultkvist Bengtsson, Ann Tronde

Publikováno v: Journal of Drug Targeting. 11:61-74

The pulmonary absorption of nine low-molecular-weight (225-430 Da) drugs (atenolol, budesonide, enalaprilat, enalapril, formoterol, losartan, metoprolol, propranolol and terbutaline) and one high-molecular-weight membrane permeability marker compound

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e9dd66a510d2856fc713fce0b47a67
https://doi.org/10.1080/1061186031000086117

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Determination of toluene diisocyanate in air using micro liquid chromatography with UV-detection

Autor: Gunnar Skarping, Per Erlandsson, Marianne Dalene, Per Brunmark, C. Dewaele, Carsten Sangö

Publikováno v: Journal of Microcolumn Separations. 3:371-375

A routine method using micro-LC for the determination of toluene diisocyanate (TDI) in air is presented. Air is sampled in impingers containing a toluene solution of 9-(N-methylaminomethyl)anthracene as derivatization reagent. The samples are evapora

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76ff9a4a12261843ca34ed180b72dc48
https://doi.org/10.1002/mcs.1220030411

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ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models

Autor: Richard Barido, Per Brunmark, Gary Anderson, Robert W. Johnson, Kimberly E. Vanover, Linda Pounds, Uli Hacksell, Mark R. Brann, Isaac Veinbergs, Agnete Dyssegaard, Douglas W. Bonhaus, Ali Tabatabaei, Luis R. Gardell, Robert E. Davis

Publikováno v: The Journal of pharmacology and experimental therapeutics. 322(2)

Dopamine D(2) receptor antagonism contributes to the therapeutic action of antipsychotic drugs (APDs) but also produces undesirable side effects, including extrapyramidal motor deficits, cognitive dulling, and prolactinemia. The introduction of atypi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfce12b5986090fed6609be94fbf0f68
https://pubmed.ncbi.nlm.nih.gov/17519387

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Identification of subdomain IB in human serum albumin as a major binding site for polycyclic aromatic hydrocarbon epoxides

Autor: Paul L. Skipper, Steven R. Tannenbaum, Per Brunmark, Shantu Amin, Shawn P. Harriman, John S. Wishnok

Publikováno v: Chemical research in toxicology. 10(8)

Covalent adducts between serum albumin and low molecular weight organic electrophiles are formed with a high degree of regioselectivity mostly for nucleophilic amino acid residues located in subdomains IIA and IIIA. Previous studies have indicated th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab22f591da707a76ece7a89072d9703
https://pubmed.ncbi.nlm.nih.gov/9282837

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Gas chromatography-negative-ion chemical ionization mass spectrometry of hydrolysed human urine and blood plasma for the biomonitoring of occupational exposure to 4,4'-methylenebisaniline

Autor: Per Brunmark, Marianne Dalene, Gunnar Skarping

Publikováno v: The Analyst. 120(1)

A gas chromatographic-mass spectrometric (GC-MS) method for the biological monitoring of 4,4'-methylenebisaniline (MDA), is presented. MDA was determined in urine and plasma after hydrolysis and analysed as the pentafluoropropionic anhydride derivati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77a43f196975e37a9c2061e00ede41a
https://pubmed.ncbi.nlm.nih.gov/7710126

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Determination of 4,4'-methylenedianiline in hydrolysed human urine by micro liquid chromatography with ultraviolet detection

Autor: Pernilla Persson, Gunnar Skarping, Per Brunmark

Publikováno v: Journal of chromatography. 579(2)

4,4'-Methylenedianiline was determined in human urine by micro liquid chromatography with ultraviolet detection. The combination of a thorough work-up and the high mass sensitivity of micro liquid chromatography gave the method very high sensitivity.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c637805dfcafc99a3a785d98e08fae
https://pubmed.ncbi.nlm.nih.gov/1429984

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