Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Per Antonson"'
Autor:
Laura Raccosta, Maura Marinozzi, Susan Costantini, Daniela Maggioni, Lorena Maria Ferreira, Gianfranca Corna, Paola Zordan, Angela Sorice, Diego Farinello, Silvia Bianchessi, Michela Riba, Dejan Lazarevic, Paolo Provero, Matthias Mack, Attilio Bondanza, Ivan Nalvarte, J-A Gustafsson, Valeria Ranzani, Francesco De Sanctis, Stefano Ugel, Silvère Baron, Jean-Marc A. Lobaccaro, Lorenzo Pontini, Manuela Pacciarini, Catia Traversari, Massimiliano Pagani, Vincenzo Bronte, Giovanni Sitia, Per Antonson, Andrea Brendolan, Alfredo Budillon, Vincenzo Russo
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-21 (2023)
Abstract Lipid and cholesterol metabolism play a crucial role in tumor cell behavior and in shaping the tumor microenvironment. In particular, enzymatic and non-enzymatic cholesterol metabolism, and derived metabolites control dendritic cell (DC) fun
Externí odkaz:
https://doaj.org/article/19a1cad6fabb42a1b5100c635b5364ef
Autor:
Xiaoyu Song, Wanfu Wu, Yubing Dai, Margaret Warner, Ivan Nalvarte, Per Antonson, Mukesh Varshney, Jan-Åke Gustafsson
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12461 (2023)
Liver X receptors (LXRα and LXRβ) are oxysterol-activated nuclear receptors that play key roles in cholesterol homeostasis, the central nervous system, and the immune system. We have previously reported that LXRαβ-deficient mice are more suscepti
Externí odkaz:
https://doaj.org/article/bdae6b7e1a6e4f4b9d2428fcc414948b
Autor:
Dan Huang, Mattias Berglund, Anastasios Damdimopoulos, Per Antonson, Cecilia Lindskog, Gunilla Enblad, Rose-Marie Amini, Sam Okret
Publikováno v:
Cancers, Vol 15, Iss 4, p 1298 (2023)
For most lymphomas, including diffuse large B-cell lymphoma (DLBCL), the male incidence is higher, and the prognosis is worse compared to females. The reasons are unclear; however, epidemiological and experimental data suggest that estrogens are invo
Externí odkaz:
https://doaj.org/article/71d2fc6066b7469fb4a13702c2fb9ab1
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3100 (2022)
The estrogen receptor beta (ERβ) is physiologically essential for reproductive biology and is implicated in various diseases. However, despite more than 20 years of intensive research on ERβ, there are still uncertainties about its distribution in
Externí odkaz:
https://doaj.org/article/b1ca12ab93654cdd96b90cda2cc212db
Autor:
Leonie Brockmann, Shiwa Soukou, Babett Steglich, Paulo Czarnewski, Lilan Zhao, Sandra Wende, Tanja Bedke, Can Ergen, Carolin Manthey, Theodora Agalioti, Maria Geffken, Oliver Seiz, Sara M. Parigi, Chiara Sorini, Jens Geginat, Keishi Fujio, Thomas Jacobs, Thomas Roesch, Jacob R. Izbicki, Ansgar W. Lohse, Richard A. Flavell, Christian Krebs, Jan-Ake Gustafsson, Per Antonson, Maria Grazia Roncarolo, Eduardo J. Villablanca, Nicola Gagliani, Samuel Huber
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Tr1 cells are considered an immunosuppressive CD4 T cell population producing IL-10. Here the authors show that IL-10 is insufficient for Tr1 immunosuppression, define surface markers and transcriptional program of the immunosuppressive subset within
Externí odkaz:
https://doaj.org/article/9965d7bfb0694a05899ad6316109497d
Autor:
Marko Matic, Galyna Bryzgalova, Hui Gao, Per Antonson, Patricia Humire, Yoko Omoto, Neil Portwood, Camilla Pramfalk, Suad Efendic, Per-Olof Berggren, Jan-Åke Gustafsson, Karin Dahlman-Wright
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217526 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0057458.].
Externí odkaz:
https://doaj.org/article/78b26e0457114b85a3e8efa161028abe
Autor:
David G. Thomas, Amanda C. Doran, Panagiotis Fotakis, Marit Westerterp, Per Antonson, Hui Jiang, Xian-Cheng Jiang, Jan-Åke Gustafsson, Ira Tabas, Alan R. Tall
Publikováno v:
Cell Reports, Vol 25, Iss 13, Pp 3774-3785.e4 (2018)
Summary: The activation of liver X receptor (LXR) promotes cholesterol efflux and repression of inflammatory genes with anti-atherogenic consequences. The mechanisms underlying the repressive activity of LXR are controversial and have been attributed
Externí odkaz:
https://doaj.org/article/75d63901b5094ee292734e51cc911855
Autor:
Per Antonson, Marko Matic, Neil Portwood, Raoul V Kuiper, Galyna Bryzgalova, Hui Gao, Sara H Windahl, Patricia Humire, Claes Ohlsson, Per-Olof Berggren, Jan-Åke Gustafsson, Karin Dahlman-Wright
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85581 (2014)
In this study we describe the reproductive phenotypes of a novel mouse model in which Cre-mediated deletion of ERα is regulated by the aP2 (fatty acid binding protein 4) promoter. ERα-floxed mice were crossed with transgenic mice expressing Cre-rec
Externí odkaz:
https://doaj.org/article/ed88f335c13244e8ac3c98cce9caa6b2
Autor:
Marko Matic, Galyna Bryzgalova, Hui Gao, Per Antonson, Patricia Humire, Yoko Omoto, Neil Portwood, Camilla Pramfalk, Suad Efendic, Per-Olof Berggren, Jan-Åke Gustafsson, Karin Dahlman-Wright
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57458 (2013)
An increasing body of evidence now links estrogenic signalling with the metabolic syndrome (MS). Despite the beneficial estrogenic effects in reversing some of the MS symptoms, the underlying mechanisms remain largely undiscovered. We have previously
Externí odkaz:
https://doaj.org/article/78c9ceb9069a42e8ae141228c6a11656
Autor:
Ivan Nalvarte, Per Antonson
Publikováno v:
Receptors. 2:116-126
Estrogens play a crucial role in sexual development and fertility as well as many other physiological processes, and it is estrogen receptors that mediate the physiological responses. To study the role of the estrogen receptors in these processes, se