Zobrazeno 1 - 10
of 348
pro vyhledávání: '"Per, Westermark"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract In order to produce artificial silk fibers with properties that match the native spider silk we likely need to closely mimic the spinning process as well as fiber architecture and composition. To increase our understanding of the structure a
Externí odkaz:
https://doaj.org/article/8888e40e4f634556aaa37fa5fe4dd942
Autor:
Justina Damjanovic Vesterlund, Elisabet Ihse, Ulrika Thelander, Alice Zancanaro, Gunilla T. Westermark, Per Westermark
Publikováno v:
Upsala Journal of Medical Sciences, Vol 127, Pp 1-8 (2022)
Diagnosis of systemic amyloidosis is a clinical challenge and usually relies on a tissue biopsy. We have developed diagnostic methods based on the presence of amyloid deposits in abdominal subcutaneous fat tissue. This tissue is also used to determin
Externí odkaz:
https://doaj.org/article/285a18c9f08e469391cc5aab4d296091
Autor:
Anna Rising, Paola Gherardi, Gefei Chen, Jan Johansson, Marie E. Oskarsson, Gunilla T. Westermark, Per Westermark
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-5 (2021)
Abstract AA amyloidosis can be transmitted experimentally in several mammalian and avian species as well as spontaneously between captive animals, even by oral intake of amyloid seeds. Amyloid seeding can cross species boundaries, and fibrils of one
Externí odkaz:
https://doaj.org/article/e6504fa2eb8649faab412890a3a44365
Autor:
Hedvig Paulsson Rokke, Nima Sadat Gousheh, Per Westermark, Ole B. Suhr, Intissar Anan, Elisabet Ihse, Björn Pilebro, Jonas Wixner
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-10 (2020)
Abstract Background The diagnostic accuracy of histopathological detection of transthyretin amyloid (ATTR) by Congo red staining of abdominal fat samples has been questioned since low sensitivity has been reported, especially for patients with ATTR c
Externí odkaz:
https://doaj.org/article/c40549b432104364b8d7c4ba08cf13ff
Autor:
Matthias Schmidt, Sebastian Wiese, Volkan Adak, Jonas Engler, Shubhangi Agarwal, Günter Fritz, Per Westermark, Martin Zacharias, Marcus Fändrich
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Systemic amyloidosis of the ATTR is one of the most abundant forms of systemic amyloidosis and caused by misfolding of the circulating blood protein transthyretin (TTR). Here the authors present the cryo-EM structure of patient-derived Val30Met ATTR
Externí odkaz:
https://doaj.org/article/1cfd6f8b528f4738ac103cd51fd0beb4
Autor:
Falk Liberta, Sarah Loerch, Matthies Rennegarbe, Angelika Schierhorn, Per Westermark, Gunilla T. Westermark, Bouke P. C. Hazenberg, Nikolaus Grigorieff, Marcus Fändrich, Matthias Schmidt
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Systemic AA amyloidosis is caused by misfolding of the acute phase protein serum amyloid A1. Here the authors present the cryo-EM structures of murine and human AA amyloid fibrils that were isolated from tissue samples and describe how the fibrils di
Externí odkaz:
https://doaj.org/article/a47ab7cd22cf43a58ce79e21f975d4b7
Autor:
Ole Bernt Suhr, Jonas Wixner, Intissar Anan, Hans-Erik Lundgren, Priyantha Wijayatunga, Per Westermark, Elisabet Ihse
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0211983 (2019)
BACKGROUND:The amyloid fibril in hereditary transthyretin (TTR) Val30Met (pVal50Met) amyloid (ATTR Val30Met) amyloidosis is composed of either a mixture of full-length and TTR fragments (Type A) or of only full-length TTR (Type B). The type of amyloi
Externí odkaz:
https://doaj.org/article/fc1362f9554241cd81fb87d00e511bfc
Autor:
Mitsuharu Ueda, Per Westermark, Maria M. Picken, Thibaud Damy, Bouke P. C. Hazenberg, Stefan Schönland, John L. Berk, Julian D. Gillmore, Angela Dispenzieri, Merrill D. Benson, Christoph Röcken, Francesca Lavatelli
Publikováno v:
Amyloid, 29(1), 8-13. Taylor & Francis Ltd
A reliable diagnosis of amyloidosis is usually based on a tissue biopsy. With increasing options for specific treatments of the different amyloid diseases, an exact and valid diagnosis including determination of the biochemical fibril nature is imper
Autor:
Joel N. Buxbaum, Angela Dispenzieri, David S. Eisenberg, Marcus Fändrich, Giampaolo Merlini, Maria J. M. Saraiva, Yoshiki Sekijima, Per Westermark
Publikováno v:
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. 29(4)
The Nomenclature Committee of the International Society of Amyloidosis met at the XVIII International Symposium on Amyloidosis in September and virtually in October 2022 with discussions resulting in this upgraded nomenclature recommendation. The nom
Autor:
Désirée S Jansson, Caroline Bröjer, Aleksija Neimanis, Torsten Mörner, Charles L Murphy, Faruk Otman, Per Westermark
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193265 (2018)
Since the late 1990s, high mortality and declining populations have been reported among sea birds including Herring gulls (Larus argentatus) from the Baltic Sea area in Northern Europe. Repeated BoNT type C/D botulism outbreaks have occurred, but it
Externí odkaz:
https://doaj.org/article/1fa46033368846a79ea7f29c8daae804