Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Per, Selnes"'
Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease
Autor:
Fernando Gonzalez-Ortiz, Bjørn-Eivind Kirsebom, José Contador, Jordan E. Tanley, Per Selnes, Berglind Gísladóttir, Lene Pålhaugen, Mathilde Suhr Hemminghyth, Jonas Jarholm, Ragnhild Skogseth, Geir Bråthen, Gøril Grøndtvedt, Atle Bjørnerud, Sandra Tecelao, Knut Waterloo, Dag Aarsland, Aida Fernández-Lebrero, Greta García-Escobar, Irene Navalpotro-Gómez, Michael Turton, Agnes Hesthamar, Przemyslaw R. Kac, Johanna Nilsson, Jose Luchsinger, Kathleen M. Hayden, Peter Harrison, Albert Puig-Pijoan, Henrik Zetterberg, Timothy M. Hughes, Marc Suárez-Calvet, Thomas K. Karikari, Tormod Fladby, Kaj Blennow
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Staging amyloid-beta (Aβ) pathophysiology according to the intensity of neurodegeneration could identify individuals at risk for cognitive decline in Alzheimer’s disease (AD). In blood, phosphorylated tau (p-tau) associates with Aβ patho
Externí odkaz:
https://doaj.org/article/b027901016fa4e8ba7386d92b8d8e45e
Autor:
Cecilia Magdalena Eriksson, Bjørn-Eivind Kirsebom, Ragna Espenes, Nikias Siafarikas, Knut Waterloo, Arvid Rongve, Per Selnes, Dag Aarsland, Tormod Fladby, Erik Hessen
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra (2024)
ABSTRACT INTRODUCTION: Depressive symptoms are associated with Alzheimer’s disease (AD), but their neurobiological and neuropsychological correlates remain poorly understood. We investigate if depressive symptoms are associated with amyloid (Aβ) p
Externí odkaz:
https://doaj.org/article/39b4331569af4ec3b84f80bb3883ae8d
Autor:
Kaja Nordengen, Bjørn-Eivind Kirsebom, Grit Richter, Lene Pålhaugen, Berglind Gísladóttir, Nikias Siafarikas, Arne Nakling, Arvid Rongve, Geir Bråthen, Gøril Rolfseng Grøntvedt, Fernando Gonzalez, Knut Waterloo, Kulbhushan Sharma, Thomas Karikari, Eleonora M. Vromen, Betty M. Tijms, Pieter J. Visser, Per Selnes, Milicia G. Kramberger, Bengt Winblad, Kaj Blennow, Tormod Fladby
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-16 (2023)
Abstract Background Brain innate immune activation is associated with Alzheimer’s disease (AD), but degrees of activation may vary between disease stages. Thus, brain innate immune activation must be assessed in longitudinal clinical studies that i
Externí odkaz:
https://doaj.org/article/e8a9047557934ffca73d41a8657fb122
Autor:
Catherine Morgan, Frederik Barkhof, David L Thomas, Saima Hilal, Moritz Brandt, Betty M Tijms, Majon Muller, Tormod Fladby, Jennifer Linn, Per Selnes, Atle Bjørnerud, Elsmarieke M van de Giessen, Beatriz Padrela, Amnah Mahroo, Mervin Tee, Markus H Sneve, Paulien Moyaert, Oliver Geier, Joost P A Kuijer, Soetkin Beun, Wibeke Nordhøy, Yufei David Zhu, Mareike A Buck, Daniel C Hoinkiss, Simon Konstandin, Jörn Huber, Julia Wiersinga, Roos Rikken, Diederick de Leeuw, Håkon Grydeland, Lynette Tippett, Erin E Cawston, Esin Ozturk-Isik, Anders Fjell, Kristine Walhovd, Lene Pålhaugen, Patricia Clement, Eric Achten, Udunna Anazodo, Klaus Eickel, Jan Petr, Matthias Günther, Henk J M M Mutsaerts
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Introduction Loss of blood-brain barrier (BBB) integrity is hypothesised to be one of the earliest microvascular signs of Alzheimer’s disease (AD). Existing BBB integrity imaging methods involve contrast agents or ionising radiation, and pose limit
Externí odkaz:
https://doaj.org/article/cb019857e39c403eb369f2a40b1fec37
Autor:
Mostafa Mehdipour Ghazi, Per Selnes, Santiago Timón-Reina, Sandra Tecelão, Silvia Ingala, Atle Bjørnerud, Bjørn-Eivind Kirsebom, Tormod Fladby, Mads Nielsen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionEfforts to develop cost-effective approaches for detecting amyloid pathology in Alzheimer's disease (AD) have gained significant momentum with a focus on biomarker classification. Recent research has explored non-invasive and readily acce
Externí odkaz:
https://doaj.org/article/5aa00918684b4d0ab048ec6a1d6f0aae
Autor:
Bradley J. MacIntosh, Qinghui Liu, Till Schellhorn, Mona K. Beyer, Inge Rasmus Groote, Pål C. Morberg, Joshua M. Poulin, Maiken N. Selseth, Ragnhild C. Bakke, Aina Naqvi, Amir Hillal, Teresa Ullberg, Johan Wassélius, Ole M. Rønning, Per Selnes, Espen S. Kristoffersen, Kyrre Eeg Emblem, Karoline Skogen, Else C. Sandset, Atle Bjørnerud
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionRadiological assessment is necessary to diagnose spontaneous intracerebral hemorrhage (ICH) and traumatic brain injury intracranial hemorrhage (TBI-bleed). Artificial intelligence (AI) deep learning tools provide a means for decision supp
Externí odkaz:
https://doaj.org/article/2623a5d887dc47b48a11c9d75ae7ecba
Autor:
Luiza Jadwiga Chwiszczuk, Monica Haraldseid Breitve, Bjørn-Eivind Bordewick Kirsebom, Per Selnes, John Chr. Fløvig, Anne-Brita Knapskog, Ragnhild E. Skogseth, Jessica Hubbers, Elin Holst-Larsen, Arvid Rongve
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
BackgroundCurrently, there are no disease-modifying pharmacological treatment options for dementia with Lewy bodies (DLB). The hallmark of DLB is pathological alpha-synuclein (aS) deposition. There are growing amounts of data suggesting that reduced
Externí odkaz:
https://doaj.org/article/584135d2a48849d1ae193b1c14f7ba68
Autor:
Klaus Thanke Aspli, Jan O. Aaseth, Trygve Holmøy, Kaj Blennow, Henrik Zetterberg, Bjørn-Eivind Kirsebom, Tormod Fladby, Per Selnes
Publikováno v:
Brain Sciences, Vol 13, Iss 11, p 1511 (2023)
Skogholt’s disease is a rare neurological disorder that is only observed in a small Norwegian kindred. It typically manifests in adulthood with uncharacteristic neurological symptoms from both the peripheral and central nervous systems. The etiolog
Externí odkaz:
https://doaj.org/article/008136d6590244e5aa5d5eafebecfc93
Autor:
Martin Soria Røvang, Per Selnes, Bradley J MacIntosh, Inge Rasmus Groote, Lene Pålhaugen, Carole Sudre, Tormod Fladby, Atle Bjørnerud
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0285683 (2023)
An important step in the analysis of magnetic resonance imaging (MRI) data for neuroimaging is the automated segmentation of white matter hyperintensities (WMHs). Fluid Attenuated Inversion Recovery (FLAIR-weighted) is an MRI contrast that is particu
Externí odkaz:
https://doaj.org/article/8162f2352df844b28e43c0b50e000f0b
Autor:
Jonas Alexander Jarholm, Atle Bjørnerud, Turi Olene Dalaker, Mehdi Sadat Akhavi, Bjørn Eivind Kirsebom, Lene Pålhaugen, Kaja Nordengen, Gøril Rolfseng Grøntvedt, Arne Nakling, Lisa F. Kalheim, Ina S. Almdahl, Sandra Tecelão, Tormod Fladby, Per Selnes
Publikováno v:
Journal of Alzheimer's Disease. :1-21
Background: Atrophy of the medial temporal lobe (MTL) is a biological characteristic of Alzheimer’s disease (AD) and can be measured by segmentation of magnetic resonance images (MRI). Objective: To assess the clinical utility of automated volumetr