Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Per, Lincoln"'
Publikováno v:
Physical Chemistry Chemical Physics. 23:2238-2244
The enantiomers of a novel mononuclear ruthenium(II) complex [Ru(phen)2bidppz]2+ with an elongated dppz moiety were synthesized. Surprisingly, the complex showed no DNA intercalating capability in an aqueous environment. However, by the addition of w
Autor:
Adam A. Jabak, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah J. McCauley, Ioulia Rouzina, Mark C. Williams, Thayaparan Paramanathan
Publikováno v:
Biophysical journal. 121(19)
Small-molecule DNA-binding drugs have shown promising results in clinical use against many types of cancer. Understanding the molecular mechanisms of DNA binding for such small molecules can be critical in advancing future drug designs. We have been
Autor:
Per Lincoln, Maryarn Nejat Dehkordi
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 38:3318-3326
Linear dichroism (LD), UV-Vis and fluorescence spectroscopy were used to investigate the interaction of the Δ- and Λ-enantiomers of the two complexes of [Ru(phen)2 2-phenylimidazophenanthroline]+2 ...
Autor:
Bobo Feng, Kai Jiang, Per Lincoln, Carlos Bustamante, Fredrik Westerlund, Alexander B. Tong, Robert P Sosa, Masayuki Takahashi, Anna K. F. Mårtensson, Kevin D. Dorfman, Bengt Nordén
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The main stabilizer of the DNA double helix is not the base-pair hydrogen bonds but coin-pile stacking of base pairs, whose hydrophobic cohesion, requiring abundant water, indirectly makes the DNA interior dry so that hydrogen bonds can
Publikováno v:
Inorganic Chemistry. 58:9452-9459
The biexponential excited-state emission decay characteristic of DNA intercalated tris-bidentate dppz-based ruthenium complexes of the general form Ru(L)2dppz2+ has previously been explained by a binding model with two distinct geometry orientations
Autor:
Maryam, Nejat Dehkordi, Per, Lincoln
Publikováno v:
Journal of biomolecular structuredynamics. 38(11)
Linear dichroism (LD), UV-Vis and fluorescence spectroscopy were used to investigate the interaction of the Δ- and Λ-enantiomers of the two complexes of [Ru(phen)
Autor:
Anna K. F. Mårtensson, Per Lincoln
Publikováno v:
Physical Chemistry Chemical Physics. 20:11336-11341
Isothermal titration calorimetry (ITC) has been utilized to investigate the effect of methyl substituents on the intercalating dppz ligand of the enantiomers of the parent complex Ru(phen)2dppz2+ (phen = 1,10-phenanthroline; dppz = dipyrido[3,2-a:2',
Autor:
Anna K. F. Mårtensson, Per Lincoln
Publikováno v:
Physical Chemistry Chemical Physics. 20:7920-7930
While isothermal titration calorimetry (ITC) is widely used and sometimes referred to as the "gold standard" for quantitative measurements of biomolecular interactions, its usage has so far been limited to the analysis of the binding to isolated, non
Publikováno v:
Chirality. 28:713-720
Metal susceptibility assays and spot plating were used to investigate the antimicrobial activity of enantiopure [Ru(phen)2 dppz]2+ (phen =1,10-phenanthroline and dppz = dipyrido[3,2-a:2´,3´-c]phenazine) and [μ-bidppz(phen)4 Ru2 ]4+ (bidppz =11,11
Publikováno v:
Inorganic chemistry. 58(14)
The biexponential excited-state emission decay characteristic of DNA intercalated tris-bidentate dppz-based ruthenium complexes of the general form Ru(L)