Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Pequita Bludeau"'
Autor:
Pequita Bludeau, Tina Fay, Bruce H. Mandt, Richard M. Allen, Colin Larson, Richard A. Deitrich, Richard A. Radcliffe
Publikováno v:
Alcohol (Fayetteville, N.Y.). 66
Individuals with a low initial response to alcohol (i.e., ethanol) are at greater risk of developing alcohol abuse or dependence later in life. Similar to humans, individual differences in ethanol sensitivity also can be seen in rats, and several lab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2552475ab504609559bce7659e8d6130
https://pubmed.ncbi.nlm.nih.gov/29182922
https://pubmed.ncbi.nlm.nih.gov/29182922
Publikováno v:
Alcohol. 41:557-566
Previous studies have identified quantitative trait loci (QTL) in the inbred high and low alcohol-sensitive rat (IHAS1 and ILAS1) strains. The original development of the strains involved selection for ethanol sensitivity based on duration of the los
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3d304196e0e0853b27e8d5e33489d6
https://doi.org/10.1016/j.alcohol.2007.10.001
https://doi.org/10.1016/j.alcohol.2007.10.001
Autor:
William Asperi, Richard A. Deitrich, Pequita Bludeau, Richard A. Radcliffe, Tina Fay, V. Gene Erwin, Xin-Sheng Deng
Publikováno v:
Psychopharmacology. 188:343-354
Genetically influenced alcohol sensitivity is thought to be an important risk factor for the development of alcoholism. An effective first step for identifying genes that mediate variation in alcohol sensitivity is through quantitative trait loci (QT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ad011ad9046b5ac2e74eb1265687b2
https://doi.org/10.1007/s00213-006-0512-2
https://doi.org/10.1007/s00213-006-0512-2
Autor:
Sarah E. Hoffmann, Tina Fay, Pequita Bludeau, Laura J. Draski, Richard A. Deitrich, Joel Edwards, Xin-Sheng Deng, Kristy Lundquist, William Asperi, Richard A. Radcliffe, V. Gene Erwin
Publikováno v:
Alcoholism: Clinical & Experimental Research. 28:1796-1804
BACKGROUND Genetic variance in initial sensitivity to ethanol has been implicated as a risk factor for the development of alcoholism. Identification of the genes that confer differential initial sensitivity is an important goal for the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5f6597e8685abdf30dd5e0cc158d85
https://doi.org/10.1097/01.alc.0000148106.71801.d7
https://doi.org/10.1097/01.alc.0000148106.71801.d7
Autor:
V. Gene Erwin, Xin-Sheng Deng, Pequita Bludeau, Richard A. Radcliffe, William Asperi, Sarah E. Hoffmann, Tina Fay, Richard A. Deitrich
Publikováno v:
Behavior Genetics. 34:453-463
The Alcohol Tolerant (AT) and Alcohol Nontolerant (ANT) rats, selectively bred for ethanol-induced ataxia on the inclined plane at ALKO in Finland, were moved to the University of Colorado in 1998. The selection phenotype was tested on generation 60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10931c20a1f4b3f601b38971c8df386
https://doi.org/10.1023/b:bege.0000023650.32243.39
https://doi.org/10.1023/b:bege.0000023650.32243.39
Autor:
Pequita Bludeau, Richard A. Deitrich
Publikováno v:
Alcoholism: Clinical & Experimental Research. 27:1236-1240
Background: We have previously demonstrated that there is an interaction between S-propranolol, a β-adrenergic blocking agent, and ethanol on the hypnotic sensitivity of inbred short- and long-sleep mice (ISS and ILS). We found that the interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6942aae450d1efb4e2f6c7f622f81784
https://doi.org/10.1097/01.alc.0000080674.94046.d9
https://doi.org/10.1097/01.alc.0000080674.94046.d9
Publikováno v:
Alcoholism: Clinical and Experimental Research. 24:595-604
Background: Genetically based risk for development of alcoholism in humans seems to be related to initial sensitivity and/or acute tolerance to ethanol. The genetic basis for the development of tolerance has received less attention than other ethanol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b1104a7bd3ceeadcee5923ba03b70ce
https://doi.org/10.1111/j.1530-0277.2000.tb02030.x
https://doi.org/10.1111/j.1530-0277.2000.tb02030.x
Autor:
Tina Fay, Pequita Bludeau, Richard A. Deitrich, V G Erwin, Richard A. Radcliffe, Kirsten L. Floyd, Xin-Sheng Deng
Publikováno v:
Genes, brain, and behavior. 8(6)
The Alcohol Tolerant and Alcohol Non-Tolerant rats (AT, ANT) were selectively bred for ethanol-induced ataxia as measured on the inclined plane. Here we report on a quantitative trait locus (QTL) study in an F(2) intercross population derived from in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65b9fd9cec0c2fe50bd9d00264f0c28
https://pubmed.ncbi.nlm.nih.gov/19500156
https://pubmed.ncbi.nlm.nih.gov/19500156
Autor:
Frank J. Gonzalez, Richard A. Deitrich, Pequita Bludeau, Vasilis Vasiliou, Dennis R. Petersen, Thomas L. Ziegler
Publikováno v:
Pharmacogenetics and genomics. 16(1)
Genetic factors are known to influence the sensitivity and tolerance to ethanol in humans and laboratory animals. Ethanol is metabolized to acetaldehyde mainly by the alcohol dehydrogenase pathway (ADHs) and, to a lesser extent, by microsomal oxidiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adfc646ce4bb3460768c1f412818837
https://pubmed.ncbi.nlm.nih.gov/16344722
https://pubmed.ncbi.nlm.nih.gov/16344722
Publikováno v:
Alcohol (Fayetteville, N.Y.). 34(2-3)
The purpose of the current study was to ascertain whether ethyl nitrite could be detected in vitro from the reaction of ethanol with peroxynitrite, as well as after administration of ethanol to mice. Ethyl nitrite analyte was determined by using gas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc51f107f3708314bbae74b2d6cd8cc2
https://pubmed.ncbi.nlm.nih.gov/15902916
https://pubmed.ncbi.nlm.nih.gov/15902916