Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Peptidylarginine deiminases"'
Autor:
Camilla Albano, Matteo Biolatti, Jasenka Mazibrada, Selina Pasquero, Francesca Gugliesi, Irene Lo Cigno, Federica Calati, Greta Bajetto, Giuseppe Riva, Gloria Griffante, Santo Landolfo, Marisa Gariglio, Marco De Andrea, Valentina Dell’Oste
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Citrullination is an emerging post-translational modification catalyzed by peptidyl-arginine deiminases (PADs) that convert peptidyl-arginine into peptidyl-citrulline. In humans, the PAD family consists of five isozymes (PADs 1-4, 6) involved in mult
Externí odkaz:
https://doaj.org/article/42f075546eb64640a5dc70ecfc043410
Autor:
Natalia Regine de França, Henri André Ménard, Maximilien Lora, Zhijie Zhou, Joyce Rauch, Carol Hitchon, Luís Eduardo Coelho Andrade, Inés Colmegna
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-11 (2022)
Abstract Background Anti-citrullinated protein antibodies (ACPAs) are highly specific for rheumatoid arthritis (RA). In vivo, ACPAs target peptidyl-citrulline epitopes (cit-) in a variety of proteins (cit-prot-ACPAs) and derived peptides (cit-pept-AC
Externí odkaz:
https://doaj.org/article/fa4f26124b0349d6892f18d4dfcd9a1b
Autor:
Sigrun Lange
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 5, Pp 934-938 (2021)
Peptidylarginine deiminases are a family of calcium-activated enzymes with multifaceted roles in physiological and pathological processes, including in the central nervous system. Peptidylarginine deiminases cause post-translational deimination/citru
Externí odkaz:
https://doaj.org/article/e6fdc8fdb98b4645b84af15604043ebe
Akademický článek
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Akademický článek
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Autor:
Laura Massarenti, Christian Enevold, Dres Damgaard, Peter Riis Hansen, Morten Frisch, Niels Ødum, Søren Jacobsen, Claus Henrik Nielsen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9536 (2022)
Epidemiologic studies have shown associations between periodontitis and rheumatoid arthritis (RA), but a causal relationship has not been established. Citrullination of gingival proteins by human peptidylarginine deiminases (PADs) or PAD from Porphyr
Externí odkaz:
https://doaj.org/article/e604a690c6634b06a6d32194c2293e1e
Autor:
Tania Colasanti, Francesca Romana Spinelli, Cristiana Barbati, Fulvia Ceccarelli, Susanna Scarpa, Marta Vomero, Cristiano Alessandri, Guido Valesini, Fabrizio Conti
Publikováno v:
Cells, Vol 11, Iss 2, p 262 (2022)
Belimumab (BLM) is a B lymphocyte stimulator (BLyS) inhibitor approved for the treatment of systemic lupus erythematosus (SLE). Autophagy is a cell survival mechanism involved in the pathogenesis of SLE. Citrullination is a post-translational modific
Externí odkaz:
https://doaj.org/article/366529d38701421195e3396a1b224ad4
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Alligators are crocodilians and among few species that endured the Cretaceous–Paleogene extinction event. With long life spans, low metabolic rates, unusual immunological characteristics, including strong antibacterial and antiviral ability, and ca
Externí odkaz:
https://doaj.org/article/f72539d008654fb99c57e9041734b7f8
Autor:
Marianne Engström, Kaja Eriksson, Linkiat Lee, Monika Hermansson, Anders Johansson, Anthony P. Nicholas, Natalija Gerasimcik, Karin Lundberg, Lars Klareskog, Anca Irinel Catrina, Tülay Yucel-Lindberg
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-14 (2018)
Abstract Background A relationship between rheumatoid arthritis (RA) and periodontitis has been suggested from findings that individuals with RA are prone to have advanced periodontitis and vice versa. In search of possible common pathogenetic featur
Externí odkaz:
https://doaj.org/article/b1b548b5f8904dbe978d82cf495aef2b
Autor:
Katerina D. Samara, Athina Trachalaki, Eliza Tsitoura, Anastasios V. Koutsopoulos, Eleni D. Lagoudaki, Ismini Lasithiotaki, George Margaritopoulos, Panagiotis Pantelidis, Eleni Bibaki, Nikolaos M. Siafakas, Nikolaos Tzanakis, Athol U. Wells, Katerina M. Antoniou
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background Increased protein citrullination and peptidylarginine deiminases (PADIs), which catalyze the citrullination process, are central in Rheumatoid arthritis pathogenesis and probably involved in the initial steps towards autoimmunity.
Externí odkaz:
https://doaj.org/article/49a20e8721654c4c93b0a10d2c7e2bbf