Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Peptidyl-Dipeptidase A/genetics"'
Autor:
James Yarmolinsky, Virginia Díez-Obrero, Tom G Richardson, Marie Pigeyre, Jennifer Sjaarda, Guillaume Paré, Venexia M Walker, Emma E Vincent, Vanessa Y Tan, Mireia Obón-Santacana, Demetrius Albanes, Jochen Hampe, Andrea Gsur, Heather Hampel, Rish K Pai, Mark Jenkins, Steven Gallinger, Graham Casey, Wei Zheng, Christopher I Amos, International Lung Cancer Consortium, PRACTICAL consortium, MEGASTROKE consortium, George Davey Smith, Richard M Martin, Victor Moreno
Publikováno v:
PLoS Medicine, Vol 19, Iss 2, p e1003897 (2022)
Yarmolinsky, J, Díez-Obrero, V, Richardson, T G, Pigeyre, M, Sjaarda, J, Paré, G, Walker, V M, Vincent, E E, Tan, V Y, Obón-Santacana, M, Albanes, D, Hampe, J, Gsur, A, Hampel, H, Pai, R K, Jenkins, M, Gallinger, S, Casey, G, Zheng, W, Amos, C I, International Lung Cancer Consortium, The PRACTICAL Consortium, The MEGASTROKE consortium, Smith, G D, Martin, R M & Moreno, V 2022, ' Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers : A mendelian randomization analysis ', PLOS Medicine, vol. 19, no. 2, e1003897 . https://doi.org/10.1371/journal.pmed.1003897
the PRACTICAL Consortium 2022, ' Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers : A mendelian randomization analysis ', PLoS Medicine, vol. 19, no. 2, e1003897 . https://doi.org/10.1371/journal.pmed.1003897
Dipòsit Digital de la UB
Universidad de Barcelona
Yarmolinsky, J, Díez-Obrero, V, Richardson, T G, Pigeyre, M, Sjaarda, J, Paré, G, Walker, V M, Vincent, E E, Tan, V Y, Obón-Santacana, M, Albanes, D, Hampe, J, Gsur, A, Hampel, H, Pai, R K, Jenkins, M, Gallinger, S, Casey, G, Zheng, W, Amos, C I, International Lung Cancer Consortium, The PRACTICAL Consortium, The MEGASTROKE consortium, Smith, G D, Martin, R M & Moreno, V 2022, ' Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers : A mendelian randomization analysis ', PLOS Medicine, vol. 19, no. 2, e1003897 . https://doi.org/10.1371/journal.pmed.1003897
the PRACTICAL Consortium 2022, ' Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers : A mendelian randomization analysis ', PLoS Medicine, vol. 19, no. 2, e1003897 . https://doi.org/10.1371/journal.pmed.1003897
Dipòsit Digital de la UB
Universidad de Barcelona
BackgroundEpidemiological studies have reported conflicting findings on the potential adverse effects of long-term antihypertensive medication use on cancer risk. Naturally occurring variation in genes encoding antihypertensive drug targets can be us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ebdcff10cb8f88caaecd212f39594e
https://doaj.org/article/34b1a0c7008a49a584262cd8aef7a5ec
https://doaj.org/article/34b1a0c7008a49a584262cd8aef7a5ec
Autor:
Alex K. Shalek, Kun Zhang, Christopher W. Peterson, Orit Rosen, Alison Yu, Robert Lafyatis, Samuel W. Kazer, Oliver Eickelberg, Sarah A. Teichmann, Mauricio Rojas, Martijn C. Nawijn, Colin D. Bingle, Thu Elizabeth Duong, Manuel Garber, Magali Plaisant, Philana Ling Lin, Christine S. Falk, Jennifer P. Wang, Xin Sun, Hengqi Betty Zheng, G. James Gatter, Sarah K. Nyquist, Malte Kühnemund, Joachim L. Schultze, Mark A. Krasnow, Maarten van den Berge, Yan Xu, Samuel J. Allon, Daniel F. Dwyer, Peter Horvath, Benjamin Doran, Brian M. Lin, Herbert B. Schiller, Blake M. Hauser, Fabian J. Theis, Avrum Spira, Paul A. Reyfman, Hans-Peter Kiem, Shaina L. Carroll, Zhiru Guo, Douglas P. Shepherd, Michael von Papen, Ian M. Mbano, Michael Farzan, Daniel Lingwood, JoAnne L. Flynn, Christoph Muus, Dana Pe'er, Stephen R. Quake, Travis K. Hughes, Sarah M. Fortune, Sten Linnarson, Chase J. Taylor, Tanya M. Laidlaw, Emma L. Rawlins, Bonnie Berger, Ashraf S. Yousif, Joakim Lundeberg, Jeffrey A. Whitsett, Ian A. Glass, Delphine Gras, Max A. Seibold, Jay Rajagopal, Jared Feldman, Victor Tkachev, Benjamin E. Mead, Joseph E. Powell, Aviv Regev, Alasdair Leslie, Robert W. Finberg, Yuming Cao, Jennifer M.S. Sucre, Marko Vukovic, Scott B. Snapper, Vincent N. Miao, Naftali Kaminski, Laure-Emmanuelle Zaragosi, Caylin G. Winchell, Faith Taliaferro, Marko Nikolic, Ilias Angelidis, Leslie S. Kean, Lucrezia Colonna, Kathleen M. Buchheit, Aaron G. Schmidt, Ramnik J. Xavier, Tushar J. Desai, Marc H. Wadsworth, Joshua A. Boyce, Alexander M. Tsankov, Nora A. Barrett, Pascal Barbry, Muzlifah Haniffa, Heiko Adler, Alvis Brazma, Hannah P. Gideon, Meshal Ansari, Jason R. Spence, Avinash Waghray, Constantine N. Tzouanas, Jose Ordovas-Montanes, Jonathan A. Kropski, Nicholas E. Banovich, Purushothama Rao Tata, Kerstin B. Meyer, Christos Samakovlis, Haeock Lee, Carly G. K. Ziegler, Alexander V. Misharin, Deborah T. Hung, Sylvie Leroy, Julia Bals, Vanessa Mitsialis, Kourosh Saeb-Parsy
Publikováno v:
Cell
Cell, 2020, 181 (5), pp.1016-1035.e19. ⟨10.1016/j.cell.2020.04.035⟩
Cell, Elsevier, 2020, 181 (5), pp.1016-1035.e19. ⟨10.1016/j.cell.2020.04.035⟩
Cell 181, 1016-1035 (2020)
Elsevier
Cell, 181(5), 1016-1035.e19. CELL PRESS
Cell, 2020, 181 (5), pp.1016-1035.e19. ⟨10.1016/j.cell.2020.04.035⟩
Cell, Elsevier, 2020, 181 (5), pp.1016-1035.e19. ⟨10.1016/j.cell.2020.04.035⟩
Cell 181, 1016-1035 (2020)
Elsevier
Cell, 181(5), 1016-1035.e19. CELL PRESS
Summary There is pressing urgency to understand the pathogenesis of the severe acute respiratory syndrome coronavirus clade 2 (SARS-CoV-2), which causes the disease COVID-19. SARS-CoV-2 spike (S) protein binds angiotensin-converting enzyme 2 (ACE2),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727543612f7db162539d6c42ca832836
https://doi.org/10.1016/j.cell.2020.04.035
https://doi.org/10.1016/j.cell.2020.04.035
Autor:
Christophe Jean-Yves Decrind, Yves Donati, Georges E. Grau, Denis R. Morel, Philippe Morel, Bara Ricou, Anastase Spiliopoulos, Nabil Mili, Sylvie Kossodo, Jinning Lou, Peter M. Suter
Publikováno v:
In vitro cellular & developmental biology. Animal, Vol. 34, No 7 (1998) pp. 529-36
Summary: Microvascular endothelial cells (MVEC), which differ from large vessel endothelial cells, have been isolated successfully from lungs of various species, including man. However, contamination by nonendothelial cells remains a major problem in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9d5e55cd0a29f78ee1e6daa4fc513c
http://doc.rero.ch/record/314647/files/11626_1998_Article_112.pdf
http://doc.rero.ch/record/314647/files/11626_1998_Article_112.pdf
Autor:
Catalina Santiago, Félix Gómez-Gallego, Marta Gonzalez-Freire, Carlos A. Muniesa, Alejandro Lucia, M. Fernández del Valle, Carl Foster, Margarita Pérez
Publikováno v:
International Journal of Sports Medicine. 30:66-72
We assessed the possible association between variants of the genes encoding for the angiotensin-converting enzyme ( ACE) and alpha-actinin-3 ( ACTN3) (both individually and combined) and several endurance phenotypic traits, e.g., peak power output (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce293dfc17acd560fff18570bee4e91
https://doi.org/10.1055/s-2008-1038677
https://doi.org/10.1055/s-2008-1038677
Autor:
Ceren Acar, Harun Evrengul, Deniz Seleci, Asuman Kaftan, Seyhan Tanriverdi, Halil Tanriverdi, Omur Kuru, Hatice Mergen
Publikováno v:
Heart and Vessels. 22:1-8
Increase in carotid artery intima-media thickness (IMT) is an early sign of atherosclerosis. Slow coronary flow (SCF) is characterized by delay of opacification of coronary arteries in coronary angiography in the absence of any evident obstructive le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d718dcd247dbc8ffed8d0c8678ed4e
https://doi.org/10.1007/s00380-006-0925-1
https://doi.org/10.1007/s00380-006-0925-1
Autor:
Ceylan Ayada, Ümran Toru, Sebahat Turgut, Osman Genç, Günfer Turgut, Server Sahin, A. Yerlikaya
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow obstruction that occurs as a result of the normal inflammatory process to protect against harmful irritants and chemicals. Another physiological regulatory process,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6d6032137ce50699698c4d9415dcd5
https://hdl.handle.net/20.500.12438/4548
https://hdl.handle.net/20.500.12438/4548
Autor:
Ioanna Bouba, Athina Tatsioni, Charilaos Kostoulas, Ioannis Georgiou, Sotirios Maranis, Sotirios Giannopoulos, Athanassios P. Kyritsis, Sofia Markoula
Publikováno v:
Journal of the Renin-Angiotensin-Aldosterone System, Vol 12 (2011)
We examined the association of the NG011648 polymorphism (insertion/deletion) of the angiotensin-converting enzyme (ACE) gene with ischaemic stroke occurrence, subtype of ischaemic stroke and ischaemic stroke patients' gender. Patients with first eve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80823a56726a80349926c0dc85832263
https://pubmed.ncbi.nlm.nih.gov/21421656
https://pubmed.ncbi.nlm.nih.gov/21421656
Autor:
Gang Xu, Dong Li, Tong Liu, Michael Shehata, Panagiotis Korantzopoulos, Xunzhang Wang, Guangping Li
AIMS: Recent observations have raised concerns regarding the activation of the renin-angiotensin system and the development of atrial fibrillation (AF). Some initial studies indicated an association between an angiotensin-converting enzyme insertion/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb34bb3b79e1ba9ba3bf6720e1ebaff
http://olympias.lib.uoi.gr/jspui/handle/123456789/23675
http://olympias.lib.uoi.gr/jspui/handle/123456789/23675
Acromegaly is associated with increased morbidity and mortality related to cardiovascular disease. Hypertension is one of the most common cardiovascular risk factors in acromegalic patients. The aim of this study was to investigate association betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e76bb23295505227da5da7e4e11c32
http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/6129
http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/6129
Autor:
Markoula, S., Giannopoulos, S., Asproudis, I., Kostoulas, C., Nikas, A., Bagli, E., Kyritsis, A. P., Ioannis Georgiou
Publikováno v:
Scopus-Elsevier
PURPOSE: Recent literature suggests a genetic component for non-arteritic anterior ischemic optic neuropathy (NAION). We examined the association of the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme gene, of the M235T pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::397c7c2bc8b55fe01b0672c8d4c7ed6c
http://olympias.lib.uoi.gr/jspui/handle/123456789/18664
http://olympias.lib.uoi.gr/jspui/handle/123456789/18664