Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Peptides/chemical synthesis"'
Autor:
Ludo Van Den Bosch, Frederic Rousseau, Emiel Michiels, Mathias De Decker, Peter Tompa, Sylvie Derclaye, Anna Bratek-Skicki, Philip Van Damme, David Alsteens, Joris Van Lindt, Donya Pakravan, Joost Schymkowitz
Publikováno v:
Biomolecules
Volume 11
Issue 4
Biomolecules, Vol. 11, no.4, p. 548 (2021)
Biomolecules, Vol 11, Iss 548, p 548 (2021)
Volume 11
Issue 4
Biomolecules, Vol. 11, no.4, p. 548 (2021)
Biomolecules, Vol 11, Iss 548, p 548 (2021)
Aggregates of TAR DNA-binding protein (TDP-43) are a hallmark of several neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS). Although TDP-43 aggregates are an undisputed pathological species at the end stage of these diseases,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd311aaacf6359f17dd6ba426b23cd54
Autor:
Luc Brunsveld, Richard G. Doveston, Loes M. Stevers, Christian Ottmann, Rens M J M de Vries, Lech-Gustav Milroy
Publikováno v:
Biochemical Journal, 474(7), 1273-1287. Portland Press Ltd.
Binding of 14-3-3 proteins to leucine-rich repeat protein kinase 2 (LRRK2) is known to be impaired by many Parkinson's disease (PD)-relevant mutations. Abrogation of this interaction is connected to enhanced LRRK2 kinase activity, which in turn is im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23dd3716e8903b1553d6d6886612596f
http://www.scopus.com/inward/record.url?scp=85016451496&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85016451496&partnerID=8YFLogxK
Publikováno v:
Biblioteca Digital de Teses e Dissertações da Universidade Estadual de Campinas (UNICAMP)
Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP
Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP
Orientador: Anita Jocelyne Marsaioli Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Química Resumo: Peptídeos são produtos naturais de grande ocorrência e possuem uma vasta gama de aplicações no campo biológico. A maneira m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3056::2ba271d61029af5ff4fd2604adbd9444
Autor:
Carsten Schmuck, Marcel Mertel, Daniel Hoffmann, David Bier, Martin Ehlers, Elsa Sanchez-Garcia, Christian Ottmann, Ludwig Ohl, Sumit Mittal, Maria Bartel, Marius Heimann, Jean-Noël Grad, Jeroen Briels
Publikováno v:
ChemBioChem, 19(6), 591-595. Wiley-VCH Verlag
14-3-3 Proteins play a central role in signalling pathways in cells: they interact as gatekeeper proteins with a huge number of binding partners. Their function as hub for intracellular communication can explain why these adapter proteins are associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28097f11b52786a72db04f4474ff5984
https://research.tue.nl/nl/publications/aec4505e-5496-44f7-a580-7c843a3b951d
https://research.tue.nl/nl/publications/aec4505e-5496-44f7-a580-7c843a3b951d
Autor:
Henning Locht, Gunnar Houen, Søren Jacobsen, Bente Jensen, Bettina Eide Holm, Christoffer Tandrup Nielsen, Anders Jørgen Svendsen, Nicole Hartwig Trier, Elke Theander, Hanne Merete Lindegaard, Julie Heiden, Ole Slot
Publikováno v:
Trier, N H, Holm, B E, Heiden, J, Slot, O, Locht, H, Jensen, B, Lindegaard, H, Svendsen, A, Nielsen, C T, Jacobsen, S, Theander, E & Houen, G 2018, ' The use of synthetic peptides for detection of anti-citrullinated protein antibodies in rheumatoid arthritis ', Journal of Immunological Methods, vol. 454, pp. 6-14 . https://doi.org/10.1016/j.jim.2017.11.004
Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology. A characteristic feature of RA is the presence of anti-citrullinated protein antibodies (ACPA). Since ACPAs are highly specific for RA and are often present before the onset of R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1651f3b73ec6fed53c7d8f79c80a50ae
https://portal.findresearcher.sdu.dk/da/publications/7ec6b29d-cfff-4f20-ba32-89d28931dc38
https://portal.findresearcher.sdu.dk/da/publications/7ec6b29d-cfff-4f20-ba32-89d28931dc38
Autor:
Christine Petit, Florent Delhommel, Benjamin Bardiaux, Julia Chamot-Rooke, Michael Nilges, Sébastien Brier, Florence Cordier, Amel Bahloul, Bertrand Raynal, Sylvie Nouaille, Nicolas Wolff, Baptiste Colcombet-Cazenave, Guillaume Bouvier
Publikováno v:
Structure
Structure, Elsevier (Cell Press), 2017, 25 (11), pp.1645-1656.e5. ⟨10.1016/j.str.2017.08.013⟩
Structure, 2017, 25 (11), pp.1645-1656.e5. ⟨10.1016/j.str.2017.08.013⟩
Structure, Elsevier (Cell Press), 2017, 25 (11), pp.1645-1656.e5. ⟨10.1016/j.str.2017.08.013⟩
Structure, 2017, 25 (11), pp.1645-1656.e5. ⟨10.1016/j.str.2017.08.013⟩
International audience; Hearing relies on the transduction of sound-evoked vibrations into electric signals, occurring in the stereocilia bundle of hair cells. The bundle is organized in a staircase pattern formed by rows of packed stereocilia. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf6c0f0829c16de0cf89456ba92ad039
https://hal-pasteur.archives-ouvertes.fr/pasteur-02883914
https://hal-pasteur.archives-ouvertes.fr/pasteur-02883914
Autor:
Mourad Barhoumi, Athanassios Tsakris, Olga S. Koutsoni, Eleni Dotsika, John G. Routsias, Ioannis D. Kyriazis, Ikram Guizani
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2017, 25 (21), pp.5904-5916. ⟨10.1016/j.bmc.2017.07.013⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2017, 25 (21), pp.5904-5916. ⟨10.1016/j.bmc.2017.07.013⟩
International audience; It is generally considered as imperative the ability to control leishmaniasis through the development of a protective vaccine capable of inducing long-lasting and protective cell-mediated immune responses. In this current stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a5ebbc1dce58424dd880c086af0195
https://pubmed.ncbi.nlm.nih.gov/28974324
https://pubmed.ncbi.nlm.nih.gov/28974324
Autor:
Karlheinz Altendorf, Norbert Sewald, Miklós Hollósi, Quirinus B. Broxterman, Jörg Christian Greie, Frank Hofmann, Elemér Vass, Bernard Kaptein, Thomas Huber, Horst Kessler, Sven Weigelt, Markus Ritzefeld, Burkhard Luy, Micha Jost, Christoph Freudenberger, Lavinia Panella, Zsuzsanna Majer
Publikováno v:
Chemistry - A European Journal. 18:478-487
The efrapeptin family of peptide antibiotics produced by the fungus Tolypocladium niveum, and the neo-efrapeptins from the fungus Geotrichum candidumare inhibitors of F(1)-ATPase with promising antitumor, antimalaria, and insecticidal activity. They
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4130cb37077a2684c0d1850ae7ecd0
https://doi.org/10.1002/chem.201102134
https://doi.org/10.1002/chem.201102134
Publikováno v:
Biomolecules
Volume 9
Issue 1
Biomolecules, Vol 9, Iss 1, p 4 (2018)
Volume 9
Issue 1
Biomolecules, Vol 9, Iss 1, p 4 (2018)
Nitric oxide (NO) is an endogenously produced molecule that has been implicated in several wound healing mechanisms. Its topical delivery may improve healing in acute or chronic wounds. In this study an antimicrobial peptide was synthesized which sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9edaccd50de7dc98614001eeeb8e9d0b
https://doi.org/10.3390/biom9010004
https://doi.org/10.3390/biom9010004
Autor:
Ancelmo Rabelo Souza
Publikováno v:
Biblioteca Digital de Teses e Dissertações da Universidade Estadual de Campinas (UNICAMP)
Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP
Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP
Orientador: Carlos Francisco Sampaio Bonafé Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia Resumo: O parvovirus suíno (PVS) é um agente infeccioso que pode causar doença de falha reprodutiva em fêmeas de suínos no p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61179a1aa1ffec803bb6101cf9df4c58