Zobrazeno 1 - 10
of 4 809
pro vyhledávání: '"Peptide-vaccine"'
Autor:
Craig A. Vincent, Silvia Remeseiro
Publikováno v:
Molecular Oncology, Vol 18, Iss 8, Pp 1849-1852 (2024)
A first‐in‐human trial demonstrated that a vaccine targeting the histone mutation H3K27M can induce an immune response, in a mutation‐specific manner, in patients with diffuse midline glioma. In a recent study by Boschert et al., the same group
Externí odkaz:
https://doaj.org/article/7eb562fca33d4a7cb5338788b4dafa4f
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract The Middle East has witnessed a greater spread of infectious Dengue viruses, with serotype 2 (DENV-2) being the most prevalent form. Through this work, multi-epitope peptide vaccines against DENV-2 that target E and nonstructural (NS1) prote
Externí odkaz:
https://doaj.org/article/62965c4cde2547b1b71d6d9eb1618030
Autor:
Lanqi Cen, Zhe Zhang, Yi Sun, Nandie Wu, Jie Shao, Zhaoye Qian, Manman Tian, Yaohua Ke, Baorui Liu
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background The clinical application of peptide vaccines in tumor immunotherapy holds significant promise. Peptide-based tumor vaccines are currently subject to certain limitations in clinical trials, including the challenge of inducing a sus
Externí odkaz:
https://doaj.org/article/d2986432684d451ebc6de3bd09004145
Autor:
Susanne Jung, Annika Nelde, Yacine Maringer, Monika Denk, Lisa Zieschang, Christine Kammer, Melek Özbek, Peter Martus, Christopher Hackenbruch, Alexander Englisch, Jonas S. Heitmann, Helmut R. Salih, Juliane S. Walz
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionAcute myeloid leukemia (AML) has a dismal prognosis, mostly due to minimal residual disease-driven relapse, making an elimination of persisting therapy-resistant leukemia progenitor/stem cells (LPCs) the main goal for novel therapies. Pep
Externí odkaz:
https://doaj.org/article/4ad85c4b3c4a4a858a9ec662b89e13e5
Autor:
Mahamudul Hasan, Shakil Ahmed, Md. Imranuzzaman, Rezaul Bari, Shiplu Roy, Md. Mahadi Hasan, Md. Mukthar Mia
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 22, Iss 3, Pp 100398- (2024)
Background: Enteric avian rotavirus (ARV) is the etiological agent of several health problems that pose a global threat to commercial chickens. Therefore, to avoid these widespread epidemics and high mortality rates, only vaccine and strict biosecuri
Externí odkaz:
https://doaj.org/article/97427a8b7be848939e30174b20c29277
Autor:
Masahiro Ogasawara
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTThis mini-review explores recent advancements in cancer vaccines that target Wilms’ tumor (WT1). Phase I/II trials of WT1 peptide vaccines have demonstrated their safety and efficacy against various cancers. Early trials employing HLA class
Externí odkaz:
https://doaj.org/article/f8e9daa8e49745e6af105fb66951b54d
Autor:
Alexander Englisch, Clara Hayn, Susanne Jung, Jonas S. Heitmann, Christopher Hackenbruch, Yacine Maringer, Annika Nelde, Marcel Wacker, Monika Denk, Lisa Zieschang, Christine Kammer, Peter Martus, Helmut R. Salih, Juliane S. Walz
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Chronic lymphocytic leukemia (CLL) is the most common form of leukemia among adults in Western countries. Despite the introduction of targeted therapies, including first-line Bruton’s tyrosine kinase inhibitor (BTKi) treatment, CLL remains largely
Externí odkaz:
https://doaj.org/article/dd7432dd452f4e3c895e7e3e1fbf5b55
Publikováno v:
Медицинская иммунология, Vol 26, Iss 2, Pp 345-354 (2024)
An important area of research concerns monitoring of immune response features in patients with SARS-CoV-2 infection as well as their analysis, as compared with characteristics of vaccine-mediated protection, in order to specify the determinants of ce
Externí odkaz:
https://doaj.org/article/5fdb628e89b14de988e46300d7801bf2
Autor:
Junfeng Zhao, Le Qin, Guorong He, Tiancheng Xie, Guanghui Hu, Furan Wang, Hongji Zhong, Jianming Zhu, Yunfei Xu
Publikováno v:
Cancer Medicine, Vol 12, Iss 23, Pp 21293-21307 (2023)
Abstract Background Glypican‐3 (GPC3) is highly expressed in testicular yolk sac tumor (TYST). GPC3 has been evaluated as a cancer vaccine for some types of tumors, but little is known on the effects of GPC3 peptide‐based therapy on TYST. Here, w
Externí odkaz:
https://doaj.org/article/9efd101904634348ba6ee0be4f57dc81
Autor:
Daniel H. Zimmerman, Zoltan Szekanecz, Adrienn Markovics, Kenneth S. Rosenthal, Roy E. Carambula, Katalin Mikecz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Rheumatoid arthritis (RA) is recognized as an autoimmune joint disease driven by T cell responses to self (or modified self or microbial mimic) antigens that trigger and aggravate the inflammatory condition. Newer treatments of RA employ monoclonal a
Externí odkaz:
https://doaj.org/article/e4aec4b93f5348f99a094ae2c4a12b9e