Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Peptide therapeutic"'
Autor:
Nico van Os, Ali Javed, Femke Broere, Albert van Dijk, Melanie D. Balhuizen, Martin van Eijk, Suzan H.M. Rooijakkers, Bart W. Bardoel, Dani A.C. Heesterbeek, Henk P. Haagsman, Edwin Veldhuizen
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 30, Iss , Pp 406-413 (2022)
ABSTRACT: Objectives: Our group recently developed a new group of antimicrobial peptides termed PepBiotics, of which peptides CR-163 and CR-172 showed optimized antibacterial activity against Pseudomonas aeruginosa and Staphylococcus aureus without i
Externí odkaz:
https://doaj.org/article/4befd28c10f3431d952e270e4740cb56
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Anjali Bajpai, Taushif Ahmad Quazi, Hong-Wen Tang, Nishat Manzar, Virender Singh, Ashwani Thakur, Bushra Ateeq, Norbert Perrimon, Pradip Sinha
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 7 (2020)
Peptide therapeutics, unlike small-molecule drugs, display crucial advantages of target specificity and the ability to block large interacting interfaces, such as those of transcription factors. The transcription co-factor of the Hippo pathway, YAP/Y
Externí odkaz:
https://doaj.org/article/f203d15dd6da49ed80256ddc04090199
Autor:
Caroline M. Li, Pouya Haratipour, Robert G. Lingeman, J. Jefferson P. Perry, Long Gu, Robert J. Hickey, Linda H. Malkas
Publikováno v:
Cells, Vol 10, Iss 11, p 2908 (2021)
Peptides are increasingly being developed for use as therapeutics to treat many ailments, including cancer. Therapeutic peptides have the advantages of target specificity and low toxicity. The anticancer effects of a peptide can be the direct result
Externí odkaz:
https://doaj.org/article/898ac45b5c99412aa0740ae2f675c8b1
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Siyu Shi, Peter K. Nguyen, Henry J. Cabral, Ramon Diez-Barroso, Paul J. Derry, Satoko M. Kanahara, Vivek A. Kumar
Publikováno v:
Bioactive Materials, Vol 1, Iss 2, Pp 109-121 (2016)
Treatment of HIV has long faced the challenge of high mutation rates leading to rapid development of resistance, with ongoing need to develop new methods to effectively fight the infection. Traditionally, early HIV medications were designed to inhibi
Externí odkaz:
https://doaj.org/article/8fc9a835c6fb40cd9d3a274f6d36b147
Autor:
Marie-Eve Beaulieu, Laura Soucek
Publikováno v:
Molecular & Cellular Oncology, Vol 6, Iss 5 (2019)
Inhibiting the nuclear protein MYC involved in the majority of human cancers has long been considered an impossible mission and several technical challenges have discouraged the development of MYC inhibitory strategies. Nevertheless, in our recent pu
Externí odkaz:
https://doaj.org/article/498adbf5db5d4ec88d0e846de3e98f32
Autor:
Christian Lampl, Antoinette MaassenVanDenBrink, Christina I. Deligianni, Raquel Gil-Gouveia, Tanvir Jassal, Margarita Sanchez-del-Rio, Uwe Reuter, Derya Uluduz, Jan Versijpt, Dena Zeraatkar, Simona Sacco
Publikováno v:
Journal of Headache and Pain, 24(1):56. Springer-Verlag Italia
Objective While there are several trials that support the efficacy of various drugs for migraine prophylaxis against placebo, there is limited evidence addressing the comparative safety and efficacy of these drugs. We conducted a systematic review an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a41a67abee22047c7bf39448d368ac92
https://doi.org/10.1186/s10194-023-01594-1
https://doi.org/10.1186/s10194-023-01594-1
Autor:
Adam C. Mirando, Raquel Lima e Silva, Zenny Chu, Peter A. Campochiaro, Niranjan B. Pandey, Aleksander S. Popel
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 5142 (2020)
Persistent inflammation is a complication associated with many ocular diseases. Changes in ocular vessels can amplify disease responses and contribute to vision loss by influencing the delivery of leukocytes to the eye, vascular leakage, and perfusio
Externí odkaz:
https://doaj.org/article/b1f7088a53f64b59a1a90b18e7aad98b
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.