Zobrazeno 1 - 10
of 476
pro vyhledávání: '"Peptide based vaccine"'
Autor:
Wei Zheng, Shixiong Li, Zhongliang Shi, Kailing Su, Yu Ding, Luyue Zhang, Qian Tang, Jiani Han, Han Zhao, Fengwei Wang, Hongru Zhang, Zhangyong Hong
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Tumor neoantigen peptide-based vaccines, systemic immunotherapies that enhance antitumor immunity by activating and expanding antigen-specific T cells, have achieved remarkable results in the treatment of a variety of solid tumors
Externí odkaz:
https://doaj.org/article/04cf4040c0c94dfba603e03929951722
Autor:
Huy Quang Quach, Tamar Ratishvili, Iana H. Haralambieva, Inna G. Ovsyannikova, Gregory A. Poland, Richard B. Kennedy
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Although neutralizing antibody is an established correlate of protection for measles, T cell-mediated responses play at least two critical roles in immunity to measles: first, through provision of ‘help’ enabling robust humoral immune re
Externí odkaz:
https://doaj.org/article/a03db61bd8554ab08f43e9d543dc09f0
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
Bladder cancer (BC) accounts for about 4% of all malignancies. Non-muscle-invasive BC, 75% of cases, is treated with transurethral resection and adjuvant intravesical instillation, while muscle-invasive BC warrants cisplatin-based perioperative chemo
Externí odkaz:
https://doaj.org/article/b75cab40967143d3bd8d621846f00dc7
Autor:
Jin-Seung Yun, A Reum Kim, Soo Min Kim, Eunkyung Shin, Sang-Jun Ha, Dokeun Kim, Hye-Sook Jeong
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
As Bacille Calmette-Guérin (BCG) vaccine’s effectiveness is limited to only children, the development of new tuberculosis (TB) vaccines is being studied using several platforms, and a novel TB vaccine that overcomes this limitation is required. In
Externí odkaz:
https://doaj.org/article/83b9f3d1879944d1ade07dd6cd565341
Publikováno v:
PeerJ Computer Science, Vol 10, p e1980 (2024)
Majority of the existing SARS-CoV-2 vaccines work by presenting the whole pathogen in the attenuated form to immune system to invoke an immune response. On the other hand, the concept of a peptide based vaccine (PBV) is based on the identification an
Externí odkaz:
https://doaj.org/article/a9689a22392a488191127bb5eb00ddbe
Autor:
Dzhemal Moten, Tsvetelina Batsalova, Desislava Apostolova, Tsvetelina Mladenova, Balik Dzhambazov, Ivanka Teneva
Publikováno v:
Advances in Respiratory Medicine, Vol 91, Iss 6, Pp 486-503 (2023)
Allergic diseases are a global public health problem that affects up to 30% of the population in industrialized societies. More than 40% of allergic patients suffer from grass pollen allergy. Grass pollen allergens of group 1 and group 5 are the majo
Externí odkaz:
https://doaj.org/article/aa76cf8674614e3b80e385be65d320be
Autor:
Luis Tataje-Lavanda, Edith Málaga, Manuela Verastegui, Egma Mayta Huatuco, Eliana Icochea, Manolo Fernández-Díaz, Mirko Zimic
Publikováno v:
BMC Veterinary Research, Vol 19, Iss 1, Pp 1-7 (2023)
Abstract Background Newcastle disease (ND) is a major threat to the poultry industry, leading to significant economic losses. The current ND vaccines, usually based on active or attenuated strains, are only partially effective and can cause adverse e
Externí odkaz:
https://doaj.org/article/2fd85235e8b542c8826040cdd52fdfe0
Publikováno v:
Bioengineering, Vol 11, Iss 8, p 791 (2024)
Respiratory syncytial virus (RSV) is a common respiratory pathogen that infects the human lungs and respiratory tract, often causing symptoms similar to the common cold. Vaccination is the most effective strategy for managing viral outbreaks. Current
Externí odkaz:
https://doaj.org/article/343a78583b09455cbaa2320c1b4e6106
Autor:
Joshua Tobias, Peter Steinberger, Joy Wilkinson, Gloria Klais, Michael Kundi, Ursula Wiedermann
Publikováno v:
Vaccines, Vol 12, Iss 7, p 795 (2024)
Immunity against respiratory pathogens is often short-term, and, consequently, there is an unmet need for the effective prevention of such infections. One such infectious disease is coronavirus disease 19 (COVID-19), which is caused by the novel Beta
Externí odkaz:
https://doaj.org/article/430b046ac7ce44ccb897f8382cc9f3a5
Publikováno v:
Bulletin of the National Research Centre, Vol 47, Iss 1, Pp 1-25 (2023)
Highlights A novel computational approach was adopted for the development of a vaccine model against lymphatic filariasis. The potential epitopes were screened to test their antigenicity, toxicity, immunogenicity, and allergenicity. The prophylactic
Externí odkaz:
https://doaj.org/article/219b9befff944bdcb996586bc27f476c