Peptide Nucleic Acid-Mediated Regulation of CRISPR-Cas9 Specificity.

Autor: Carufe KEW; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Genetics, Yale School of Medicine, New Haven, Connecticut, USA., Economos NG; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Genetics, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Glazer PM; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Genetics, Yale School of Medicine, New Haven, Connecticut, USA.

Publikováno v: Nucleic acid therapeutics [Nucleic Acid Ther] 2024 Oct; Vol. 34 (5), pp. 245-256. Date of Electronic Publication: 2024 Jul 22.

Peptide nucleic acids can form hairpins and bind RNA-binding proteins.

Autor: Zhong Y; Currently or formerly at School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW, Australia., Wilkinson-White L; Sydney Analytical Core Research Facility, The University of Sydney, Sydney, NSW, Australia., Zhang E; Currently or formerly at School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW, Australia., Mohanty B; Sydney Analytical Core Research Facility, The University of Sydney, Sydney, NSW, Australia., Zhang BB; Currently or formerly at School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW, Australia., McRae MS; Currently or formerly at School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW, Australia., Luo R; Currently or formerly at School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW, Australia., Allport TA; Currently or formerly at School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW, Australia., Duff AP; National Deuteration Facility, ANSTO, Lucas Heights, NSW, Australia., Zhao J; Currently or formerly at School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW, Australia., El-Kamand S; School of Science, Western Sydney University, Penrith, NSW, Australia., Du Plessis MD; School of Science, Western Sydney University, Penrith, NSW, Australia., Cubeddu L; Currently or formerly at School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW, Australia.; School of Science, Western Sydney University, Penrith, NSW, Australia., Gamsjaeger R; Currently or formerly at School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW, Australia.; School of Science, Western Sydney University, Penrith, NSW, Australia., Ataide SF; Currently or formerly at School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW, Australia., Kwan AH; Currently or formerly at School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW, Australia.

Publikováno v: PloS one [PLoS One] 2024 Sep 16; Vol. 19 (9), pp. e0310565. Date of Electronic Publication: 2024 Sep 16 (Print Publication: 2024).

Radionuclide therapy of bevacizumab-based PNA-mediated pretargeting.

Autor: Yan J; Department of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, .; Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, ., Zhao P; Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, .; National Health Commission Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital), National Health Commission of the People's Republic of China and .; Key Laboratory of Nuclear Medicine and Molecular Imaging of Sichuan Province, People's Government of Sichuan Province, Mianyang, China., Li Y; Department of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, .; Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, ., Wang J; Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, .; National Health Commission Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital), National Health Commission of the People's Republic of China and .; Key Laboratory of Nuclear Medicine and Molecular Imaging of Sichuan Province, People's Government of Sichuan Province, Mianyang, China., Yang X; Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, .; National Health Commission Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital), National Health Commission of the People's Republic of China and .; Key Laboratory of Nuclear Medicine and Molecular Imaging of Sichuan Province, People's Government of Sichuan Province, Mianyang, China., Li H; Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, ., Zhuo L; Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, .; National Health Commission Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital), National Health Commission of the People's Republic of China and .; Key Laboratory of Nuclear Medicine and Molecular Imaging of Sichuan Province, People's Government of Sichuan Province, Mianyang, China., Liao W; Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, .; National Health Commission Key Laboratory of Nuclear Technology Medical Transformation (Mianyang Central Hospital), National Health Commission of the People's Republic of China and .; Key Laboratory of Nuclear Medicine and Molecular Imaging of Sichuan Province, People's Government of Sichuan Province, Mianyang, China., Fan W; Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, ., Jia Y; Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, ., Wei H; Department of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, .; Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, ., Chen Y; Department of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, .; Key Laboratory of Nuclear Medicine and Molecular Imaging of Sichuan Province, People's Government of Sichuan Province, Mianyang, China.

Publikováno v: Nuclear medicine communications [Nucl Med Commun] 2024 Nov 01; Vol. 45 (11), pp. 901-909. Date of Electronic Publication: 2024 Jul 16.

Engineering of a DNA/γPNA Hybrid Nanoreporter for ctDNA Mutation Detection via γPNA Urinalysis.

Autor: Xiang Z; Department of Gastrointestinal Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou Medical University, Wenzhou, 325027, China.; Departments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore, 119074, Singapore., Lu J; Department of Gastrointestinal Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou Medical University, Wenzhou, 325027, China., Ming Y; Departments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore, 119074, Singapore., Guo W; Department of Minimally Invasive Interventional Radiology, The State Key Laboratory of Respiratory Disease, School of Biomedical Engineering & The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, China., Chen X; Departments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore, 119074, Singapore.; Clinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore.; Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore.; Theranostics Center of Excellence (TCE), Yong Loo Lin School of Medicine, National University of Singapore, 11 Biopolis Way, Helios, Singapore, 138667, Singapore.; Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore., Sun W; Department of Gastrointestinal Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou Medical University, Wenzhou, 325027, China.

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Sep; Vol. 11 (33), pp. e2310225. Date of Electronic Publication: 2024 Jul 03.

Innovative PNA-LB mediated allele-specific LAMP for KRAS mutation profiling on a compact lab-on-a-disc device.

Autor: Mirlohi MS; Clinical Biochemistry Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Pishbin E; Bio-microfluidics Laboratory, Department of Electrical Engineering and Information Technology, Iranian Research Organization for Science and Technology, Tehran, Iran. Electronic address: es.pishbin@gmil.com., Dezhkam R; Department of Mechanical Engineering, Sharif University of Technology, Tehran, Iran; Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA., Kiani MJ; School of Mechanical Engineering, Iran University of Science and Technology, Tehran, Iran., Shamloo A; Department of Mechanical Engineering, Sharif University of Technology, Tehran, Iran., Salami S; Clinical Biochemistry Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: salami.si@gmail.com.

Publikováno v: Talanta [Talanta] 2024 Aug 15; Vol. 276, pp. 126224. Date of Electronic Publication: 2024 May 06.