Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Peptide Fragments/genetics"'
Autor:
Rebourcet, Diane, Darbey, Annalucia, Monteiro, Ana, Soffientini, Ugo, Tsai, Yi Ting, Handel, Ian, Pitetti, Jean-Luc, Nef, Serge, Smith, Lee B., O'Shaughnessy, Peter J.
Publikováno v:
Rebourcet, D, Darbey, A, Monteiro, A, Soffientini, U, Tsai, Y T, Handel, I, Pitetti, J-L, Nef, S, Smith, L & O'Shaughnessy, P J 2017, ' Sertoli cell number defines and predicts germ and Leydig cell population sizes in the adult mouse testis ', Endocrinology, vol. 158, no. 9, pp. 2955–2969 . https://doi.org/10.1210/en.2017-00196
Endocrinology, Vol. 158, No 9 (2017) pp. 2955-2969
Endocrinology
Endocrinology, Vol. 158, No 9 (2017) pp. 2955-2969
Endocrinology
Sertoli cells regulate differentiation and development of the testis and are essential for maintaining adult testis function. To model the effects of dysregulating Sertoli cell number during development or aging, we have used acute diphtheria toxin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7cb1b9418833e4c4f848f614beccbbde
https://hdl.handle.net/20.500.11820/5cda6c99-19d7-485d-8ec0-4c39a785e238
https://hdl.handle.net/20.500.11820/5cda6c99-19d7-485d-8ec0-4c39a785e238
Autor:
Tony A. Rodrigues, Aurora Barros-Barbosa, Ana G. Pedrosa, Jorge E. Azevedo, Ana F. Dias, Tânia Francisco
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
A remarkable property of the machinery for import of peroxisomal matrix proteins is that it can accept already folded proteins as substrates. This import involves binding of newly synthesized proteins by cytosolic peroxisomal biogenesis factor 5 (PEX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f48b33e77a0947decee710e624b6ca2
https://europepmc.org/articles/PMC5602389/
https://europepmc.org/articles/PMC5602389/
Autor:
April C. Pettit, Andrew J.M. Nel, David W. Wright, Carlos Zamudio, Frederick R. Haselton, Mark L. Baglia, Megan E. Pask, Keersten M. Ricks, Keertan Dheda, Hali Bordelon, Francesca Solinas, Patricia K. Russ, Tatiana Cáceres, Philip A. Short, Jonathan Michael Blackburn
Urine samples are increasingly used for diagnosing infections including Escherichia coli, Ebola virus, and Zika virus. However, extraction and concentration of nucleic acid biomarkers from urine is necessary for many molecular detection strategies su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7c930098e0834861b260dcd4529acd
https://hdl.handle.net/20.500.12866/4631
https://hdl.handle.net/20.500.12866/4631
Autor:
Inoue, D., Kitaura, J., Togami, K., Nishimura, K., Enomoto, Y., Uchida, T., Kagiyama, Y., Kawabata, K. C., Nakahara, F., Izawa, K., Oki, T., Maehara, A., Isobe, M., Tsuchiya, A., Harada, Y., Harada, H., Ochiya, T., Aburatani, H., Kimura, Hiroshi, Thol, F., Heuser, M., Levine, R. L., Abdel-Wahab, O., Kitamura, T.
Publikováno v:
Journal of Clinical Investigation. 123:4627-4640
Recurrent mutations in the gene encoding additional sex combs-like 1 (ASXL1) are found in various hematologic malignancies and associated with poor prognosis. In particular, ASXL1 mutations are common in patients with hematologic malignancies associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55df7e4ea7cadbfc81c3a85ca2105bcc
https://doi.org/10.1172/jci70739
https://doi.org/10.1172/jci70739
Publikováno v:
Free Radical Biology and Medicine
Free Radical Biology and Medicine, vol. 53, no. 4, pp. 926-935
Free Radical Biology and Medicine, vol. 53, no. 4, pp. 926-935
Peroxynitrite (PN) is a potent nitrating and oxidizing agent generated during various pathological situations affecting the heart. The negative effects of PN result, at least in part, from its ability to activate caspases and apoptosis. RasGAP is a u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d22e768ae207233a8585c4b121490b
Autor:
Joël Walicki, Christian Widmann, Jean-Pierre Hornung, Gilles Dubuis, Evrim Jaccard, Natasa Bulat, Jiang-Yan Yang, Bernard Thorens
Publikováno v:
Diabetes, vol. 58, no. 11, pp. 2596-2606
Diabetes
Diabetes
OBJECTIVE Our laboratory has previously established in vitro that a caspase-generated RasGAP NH2-terminal moiety, called fragment N, potently protects cells, including insulinomas, from apoptotic stress. We aimed to determine whether fragment N can i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331aeba573fda1abf6a6b346c0138567
https://doi.org/10.2337/db09-0104
https://doi.org/10.2337/db09-0104
Autor:
Hanifa Bouzourene, Gabriel Bricard, Jean Claude R Givel, Pedro M. S. Alves, Theres Fagerberg, Frédéric Lévy, Olivier Michielin, Henri Vuilleumier, Daniel E. Speiser, Sebastien Viatte, Pedro Romero, Thorsten Kruger, Jean Charles Cerottini
Publikováno v:
Cancer immunology, immunotherapy, vol. 56, no. 11, pp. 1795-1805
Carcinoembryonic antigen (CEACAM5) is commonly overexpressed in human colon cancer. Several antigenic peptides recognized by cytolytic CD8+ T-cells have been identified and used in colon cancer phase-I vaccination clinical trials. The HLA-A*0201-bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca2bca08684f86ca0949ef4b4e3a580
https://doi.org/10.1007/s00262-007-0323-2
https://doi.org/10.1007/s00262-007-0323-2
Autor:
Christian Widmann, David Viertl, Benoit Lhermitte, David Barras, Girieca Lorusso, Curzio Rüegg
Publikováno v:
International Journal of Cancer. Journal International Du Cancer, vol. 135, no. 1, pp. 242-247
The p120 RasGAP protein negatively regulates Ras via its GAP domain. RasGAP carries several other domains that modulate several signaling molecules such as Rho. RasGAP is also a caspase-3 substrate. One of the caspase-3-generated RasGAP fragments, co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18959e564ce0b3a472771f3bb8f5d86
https://serval.unil.ch/resource/serval:BIB_1FACF08B8A65.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_1FACF08B8A65.P001/REF.pdf
Functional role of the noncatalytic domains of elongation factor Tu in the interactions with ligands
Publikováno v:
Biochemistry
Biochemistry, 37(2), 486-495. AMER CHEMICAL SOC
Biochemistry, 37(2), 486-495. AMER CHEMICAL SOC
Elongation factor (EF) Tu from Escherichia coli contains three domains, of which domain 1 (N-terminal domain) harbors the site for nucleotide binding and GTP hydrolysis. To analyze the function of domains 2 [middle (M) domain] and 3 [C-terminal (C) d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9037ad4f13121dd2a5a7c9ad6286604
https://research.rug.nl/en/publications/f01570b0-db83-4cbf-b0d0-06ba751c879f
https://research.rug.nl/en/publications/f01570b0-db83-4cbf-b0d0-06ba751c879f
Autor:
Nicolai S. C. van Oers, Christopher A. Parks, Adam G. Schrum, Diana Gil, Travis Kruger, Javier de la Cruz, Robert L. Silge, Immanuel F. Luescher
Publikováno v:
Journal of Immunology, vol. 186, no. 4, pp. 2282-2290
The CD3ε cytoplasmic tail contains a conserved proline-rich sequence (PRS) that influences TCR–CD3 expression and signaling. Although the PRS can bind the SH3.1 domain of the cytosolic adapter Nck, whether the PRS is constitutively available for N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e4c4edbcdd1457f97ef71ed652c53f
https://serval.unil.ch/resource/serval:BIB_30DFEE291106.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_30DFEE291106.P001/REF.pdf