Výsledky vyhledávání - "Peptide Fragments/chemical synthesis"

Trimeric heptad repeat synthetic peptides HR1 and HR2 efficiently inhibit HIV-1 entry

Autor: Mzoughi, Olfa, Teixido, Meritxell, Planès, Rémi, Serrero, Manutea, Hamimed, Ibtissem, Zurita, Esther, Moreno, Miguel, Granados, Giovana, Lakhdar-Ghazal, Faouzi, BenMohamed, Lbachir, Giralt, Ernest, Bahraoui, Elmostafa

Publikováno v: Bioscience Reports
Bioscience Reports, 2019, 39 (9), pp.1-15. ⟨10.1042/BSR20192196⟩
Bioscience reports, vol 39, iss 9

International audience; The trimeric heptad repeat domains HR1 and HR2 of the human immunodeficiency virus 1 (HIV-1) gp41 play a key role in HIV-1-entry by membrane fusion. To develop efficient inhibitors against this step, the corresponding trimeric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d6dfc3e3783a50d8ce5ed458ed29d60e
https://doi.org/10.1042/BSR20192196

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A Novel Population of Human Melanoma-Specific CD8 T Cells Recognizes Melan-A MART-1 Immunodominant Nonapeptide but Not the Corresponding Decapeptide

Autor: Laurent Derré, Cédric Touvrey, Olivier Michielin, Pedro Romero, Frédéric Lévy, Daniel E. Speiser, Estelle Devevre, Vincent Zoete, Mathias Ferber, Antoine Leimgruber

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2007, 179 (11), pp.7635-7645. ⟨10.4049/jimmunol.179.11.7635⟩
Journal of Immunology, vol. 179, no. 11, pp. 7635-7645

HLA-A2-restricted cytolytic T cells specific for the immunodominant human tumor Ag Melan-AMART-1 can kill most HLA-matched melanoma cells, through recognition of two naturally occurring antigenic variants, i.e., Melan-A nonamer AAGIGILTV and decamer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5127e4e405c1afc0d7c5d1e1084b522a
https://hal.sorbonne-universite.fr/hal-02569378

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Altered ligands reveal limited plasticity in the T cell response to a pathogenic epitope

Autor: Jacques A. Louis, Scott Southwood, Sabine Pingel, Deborah J. Fowell, Alessandro Sette, Christoph W. Turck, Nicolas Glaichenhaus, Richard M. Locksley, Pascal Launois

Publikováno v: Journal of Experimental Medicine, vol. 189, no. 7, pp. 1111-1120
The Journal of Experimental Medicine
The Journal of experimental medicine, vol 189, iss 7

Experimental leishmaniasis offers a well characterized model of T helper type 1 cell (Th1)-mediated control of infection by an intracellular organism. Susceptible BALB/c mice aberrantly develop Th2 cells in response to infection and are unable to con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68a3a96f2ddecb86b861d77d27c718e
https://serval.unil.ch/notice/serval:BIB_0F857F399BBF

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DNA binding properties of a chemically synthesized DNA binding domain of hRFX1

Autor: Wolfgang Schüler, Walter Reith, Bernard P. Roques, Christine Lenoir, Fabrice Cornille, P. Emery, Bernard Mach

Publikováno v: Nucleic Acids Research, Vol. 26, No 9 (1998) pp. 2143-2149

The RFX DNA binding domain (DBD) is a novel highly conserved motif belonging to a large number of dimeric DNA binding proteins which have diverse regulatory functions in eukaryotic organisms, ranging from yeasts to human. To characterize this novel m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b074d5efc57477e71b3298225b2f47ec
https://archive-ouverte.unige.ch/unige:11209

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A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus

Autor: Bernard Lebleu, Priscille Brodin, Eric Vivès

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1997, 272 (25), pp.16010--7. ⟨10.1074/jbc.272.25.16010⟩

Tat is an 86-amino acid protein involved in the replication of human immunodeficiency virus type 1 (HIV-1). Several studies have shown that exogenous Tat protein was able to translocate through the plasma membrane and to reach the nucleus to transact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fb0838c883f28bb327e25f10a64fd6
https://hal.archives-ouvertes.fr/hal-02194312

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One-step isocratic high-performance liquid chromatographic purification of radioiodinated and radioiodinated-photoactivable derivatives of cholecystokinin

Autor: Christophe J, Michal Svoboda, Monique Lambert, Luis Moroder

Publikováno v: Journal of chromatography, 296 (C

N-Hydroxysuccinimidyl-3-(4-hydroxy-3-[1 2 5I]iodophenyl)propionate (the Bolton-Hunter Reagent) was conjugated with (Thr 34, NLeu 37) cholecystokinin (CCK)31 - 39 in anhydrous dimethylformamide-pyridine in 20% yield. The radiolabelled peptide was puri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bde20b701ac288432095f145a7f9fa9
https://pubmed.ncbi.nlm.nih.gov/6090486

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