Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Peptide Fragments/cerebrospinal fluid"'
Autor:
Pocevičiūtė, Dovilė, Nuñez-Diaz, Cristina, Roth, Bodil, Janelidze, Shorena, Giannisis, Andreas, Hansson, Oskar, Wennström, Malin
Publikováno v:
Alzheimer's Research & Therapy, 14(1). BioMed Central
Background Alzheimer’s disease (AD) is foremost characterized by β-amyloid (Aβ)-extracellular plaques, tau-intraneuronal fibrillary tangles (NFT), and neuroinflammation, but over the last years it has become evident that peripheral inflammation m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef7c6cecafd46218690474660fdcf38
https://pure.knaw.nl/portal/en/publications/88552aa0-acd0-4d49-be93-9829850b842b
https://pure.knaw.nl/portal/en/publications/88552aa0-acd0-4d49-be93-9829850b842b
Autor:
Frans R.J. Verhey, Lieke L. Smits, Huiberdina L. Koek, Wiesje M. van der Flier, Peter Paul De Deyn, Geert Jan Biessels, Pauline Aalten, Janne M. Papma, Inez H.G.B. Ramakers, Coen D.A. Stehouwer, Marcel Olde-Rikkert, Stefan L.C. Geijselaers, Annemieke C. Heijboer, Charlotte E. Teunissen, Fransje E. Reesink
Publikováno v:
Journal of Alzheimer's Disease, 61, 1, pp. 309-320
Journal of Alzheimers Disease, 61(1), 309-320. IOS Press BV
Journal of Alzheimer’s Disease, 61(1), 309-320. IOS Press
Journal of Alzheimer's Disease, 61(1), 309-320. IOS Press
Journal of Alzheimer's Disease
Geijselaers, S L C, Aalten, P, Ramakers, I H G B, De Deyn, P P, Heijboer, A C, Koek, H L, Olderikkert, M G M, Papma, J M, Reesink, F E, Smits, L L, Stehouwer, C D A, Teunissen, C E, Verhey, F R J, Van Der Flier, W M & Biessels, G J 2017, ' Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer's Disease ', Journal of Alzheimer's Disease, vol. 61, no. 1, pp. 309-320 . https://doi.org/10.3233/JAD-170522
Journal of Alzheimer's Disease, 61(1), 309. IOS Press
Journal of Alzheimer's Disease, 61, 309-320
Journal of Alzheimers Disease, 61(1), 309-320. IOS Press BV
Journal of Alzheimer’s Disease, 61(1), 309-320. IOS Press
Journal of Alzheimer's Disease, 61(1), 309-320. IOS Press
Journal of Alzheimer's Disease
Geijselaers, S L C, Aalten, P, Ramakers, I H G B, De Deyn, P P, Heijboer, A C, Koek, H L, Olderikkert, M G M, Papma, J M, Reesink, F E, Smits, L L, Stehouwer, C D A, Teunissen, C E, Verhey, F R J, Van Der Flier, W M & Biessels, G J 2017, ' Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer's Disease ', Journal of Alzheimer's Disease, vol. 61, no. 1, pp. 309-320 . https://doi.org/10.3233/JAD-170522
Journal of Alzheimer's Disease, 61(1), 309. IOS Press
Journal of Alzheimer's Disease, 61, 309-320
BACKGROUND: Abnormal insulin signaling in the brain has been linked to Alzheimer's disease (AD).OBJECTIVE: To evaluate whether cerebrospinal fluid (CSF) insulin levels are associated with cognitive performance and CSF amyloid-β and Tau. Additionally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c053091c515e8ab1432707f2b80688e
https://doi.org/10.3233/jad-170522
https://doi.org/10.3233/jad-170522
Autor:
Aikaterini Oikonomidi, John Corthésy, Jérôme Wojcik, Gene L. Bowman, Hugues Henry, Antonio Núñez Galindo, Loïc Dayon, Ornella Cominetti, Julius Popp, Eugenia Migliavacca
Publikováno v:
Journal of Alzheimer's Disease, Vol. 60, No 4 (2017) pp. 1641-1652
Journal of Alzheimer's disease, vol. 60, no. 4, pp. 1641-1652
Journal of Alzheimer's disease, vol. 60, no. 4, pp. 1641-1652
Cerebrospinal fluid (CSF) biomarkers of the beta-amyloid and microtubule associated protein tau metabolism have proven the capacity to improve classification of subjects developing Alzheimer's disease (AD). The blood plasma proteome was characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a966e22661d220d7dba459211a2c04
https://doi.org/10.3233/jad-170426
https://doi.org/10.3233/jad-170426
Publikováno v:
Journal of psychiatric research
Journal of Psychiatric Research, Vol. 90 (2017) pp. 12-20
Journal of psychiatric research, vol. 90, pp. 12-20
Journal of Psychiatric Research, Vol. 90 (2017) pp. 12-20
Journal of psychiatric research, vol. 90, pp. 12-20
Specific changes in personality profiles may represent early non-cognitive symptoms of Alzheimer's disease (AD). Evaluating the subject's personality changes may add significant clinical information, as well as help to better understand the interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ab99e507b7fb0f90d86f4bce899907
https://doi.org/10.1016/j.jpsychires.2016.12.024
https://doi.org/10.1016/j.jpsychires.2016.12.024
Publikováno v:
Neurobiology of Aging, Vol. 52 (2017) pp. 196-213
Novel diagnostic criteria for Alzheimer's disease (AD) incorporate biomarkers, but their maturity for implementation in clinical practice at the prodromal stage (mild cognitive impairment [MCI]) is unclear. Here, we evaluate cerebrospinal fluid (CSF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff0c4ec0df10beb58e039e53291c80e
https://doi.org/10.1016/j.neurobiolaging.2016.02.034
https://doi.org/10.1016/j.neurobiolaging.2016.02.034
Autor:
Jérôme Wojcik, Aikaterini Oikonomidi, John Corthésy, Antonio Núñez Galindo, Gene L. Bowman, India Severin, Ornella Cominetti, Julius Popp, Loïc Dayon, Martin Kussmann, Hugues Henry, Eugenia Migliavacca
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2018)
Alzheimer's Research & Therapy
Alzheimer's research & therapy, vol. 10, no. 1, pp. 66
Alzheimer's Research & Therapy
Alzheimer's research & therapy, vol. 10, no. 1, pp. 66
Background Altered proteome profiles have been reported in both postmortem brain tissues and body fluids of subjects with Alzheimer disease (AD), but their broad relationships with AD pathology, amyloid pathology, and tau-related neurodegeneration ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3cb91840bd5d639f44e286352ad06f
https://doi.org/10.1186/s13195-018-0397-4
https://doi.org/10.1186/s13195-018-0397-4
Autor:
Alexander Semmler, Johannes Kornhuber, Piotr Lewczuk, Aikaterini Oikonomidi, Julius Popp, Michael Linnebank, Yvo M. Smulders
Publikováno v:
Journal of neurochemistry
Journal of Neurochemistry, 139(2), 324-332. Wiley-Blackwell
Journal of Neurochemistry, Vol. 139, No 2 (2016) pp. 324-332
Oikonomidi, A, Lewczuk, P, Kornhuber, J, Smulders, Y, Linnebank, M, Semmler, A & Popp, J 2016, ' Homocysteine metabolism is associated with cerebrospinal fluid levels of soluble amyloid precursor protein and amyloid beta ', Journal of Neurochemistry, vol. 139, no. 2, pp. 324-332 . https://doi.org/10.1111/jnc.13766
Journal of Neurochemistry, 139(2), 324-332. Wiley-Blackwell
Journal of Neurochemistry, Vol. 139, No 2 (2016) pp. 324-332
Oikonomidi, A, Lewczuk, P, Kornhuber, J, Smulders, Y, Linnebank, M, Semmler, A & Popp, J 2016, ' Homocysteine metabolism is associated with cerebrospinal fluid levels of soluble amyloid precursor protein and amyloid beta ', Journal of Neurochemistry, vol. 139, no. 2, pp. 324-332 . https://doi.org/10.1111/jnc.13766
Disturbed homocysteine metabolism may contribute to amyloidogenesis by modulating the amyloid precursor protein (APP) production and processing. The objective of this study was to investigate the relationships between cerebral amyloid production and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29674c508514c288e2c838cb2d48c69
Autor:
Hanne Struyfs, Ulf Andreasson, Daniëlle Hernalsteen, Erik Portelius, Christine Van Broeckhoven, Kaj Blennow, Eugeen Vanmechelen, Didier De Surgeloose, Dirk Jacobs, Ann De Vos, Henrik Zetterberg, Caroline Robberecht, Erik Fransen, Kerstin Andersson, Kristel Sleegers, Sebastiaan Engelborghs
Publikováno v:
Alzheimer's & Dementia. 11(12):1461-1469
Introduction Biomarkers monitoring synaptic degeneration/loss would be valuable for Alzheimer's disease (AD) diagnosis. Postsynaptic protein neurogranin may be a promising cerebrospinal fluid (CSF) biomarker but has not yet been evaluated as a plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ce2cfdd5f679b0246d7f8f7a200441
Autor:
Lautner, Ronald, Insel, Philip S., Skillbäck, Tobias, Olsson, Bob, Landén, Mikael, Frisoni, Giovanni B., Herukka, Sanna-Kaisa, Hampel, Harald, Wallin, Anders, Minthon, Lennart, Hansson, Oskar, Blennow, Kaj, Mattsson, Niklas, Zetterberg, Henrik
Publikováno v:
Alzheimer's Research and Therapy
Alzheimer's Research and Therapy, 2017, 9, pp.87. ⟨10.1186/s13195-017-0313-3⟩
Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-7 (2017)
Alzheimer's Research & Therapy, Vol. 9, No 1 (2017) P. 87
Alzheimer's Research & Therapy
Alzheimer's Research and Therapy, BioMed Central, 2017, 9, pp.87. ⟨10.1186/s13195-017-0313-3⟩
Alzheimers Research & Therapy
Alzheimer's Research and Therapy, 2017, 9, pp.87. ⟨10.1186/s13195-017-0313-3⟩
Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-7 (2017)
Alzheimer's Research & Therapy, Vol. 9, No 1 (2017) P. 87
Alzheimer's Research & Therapy
Alzheimer's Research and Therapy, BioMed Central, 2017, 9, pp.87. ⟨10.1186/s13195-017-0313-3⟩
Alzheimers Research & Therapy
International audience; BackgroundFrom earlier studies it is known that the APOE ε2/ε3/ε4 polymorphism modulates the concentrations of cerebrospinal fluid (CSF) beta-amyloid1–42 (Aβ42) in patients with cognitive decline due to Alzheimer’s dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::39be89413517d88ae8c6c8c3093a7a9e
https://hal.sorbonne-universite.fr/hal-01629381/document
https://hal.sorbonne-universite.fr/hal-01629381/document
Publikováno v:
Acta Neurologica Belgica
Acta neurologica Belgica
Acta neurologica Belgica
This review focusses on the validation and standardization of Alzheimers disease (AD) cerebrospinal fluid (CSF) biomarkers, as well as on the current clinical indications and rational use of CSF biomarkers in daily clinical practice. The validated AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4d1ffcf581126eb4439192adcc410c
https://doi.org/10.1007/s13760-017-0816-5
https://doi.org/10.1007/s13760-017-0816-5