Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Pepijn Schellen"'
Autor:
Nik Sol, Sjors G.J.G. in ‘t Veld, Adrienne Vancura, Maud Tjerkstra, Cyra Leurs, François Rustenburg, Pepijn Schellen, Heleen Verschueren, Edward Post, Kenn Zwaan, Jip Ramaker, Laurine E. Wedekind, Jihane Tannous, Bauke Ylstra, Joep Killestein, Farrah Mateen, Sander Idema, Philip C. de Witt Hamer, Anna C. Navis, William P.J. Leenders, Ann Hoeben, Bastiaan Moraal, David P. Noske, W. Peter Vandertop, R. Jonas A. Nilsson, Bakhos A. Tannous, Pieter Wesseling, Jaap C. Reijneveld, Myron G. Best, Thomas Wurdinger
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 7, Pp 100101- (2020)
Summary: Tumor-educated platelets (TEPs) are potential biomarkers for cancer diagnostics. We employ TEP-derived RNA panels, determined by swarm intelligence, to detect and monitor glioblastoma. We assessed specificity by comparing the spliced RNA pro
Externí odkaz:
https://doaj.org/article/3c63ceb85e20460e8535824c45ce6bd6
Autor:
Johannes M. Heuckmann, Martin L. Sos, Lukas Heukamp, Jürgen Wolf, Frank Griesinger, Reinhard Büttner, Erik Thunnissen, Roopika Menon, Tobias Zacherle, Gunther Hartmann, Pepijn Schellen, Thomas Wurdinger, Alexander Kluge, Thorsten Persigehl, Carsten Kobe, Juliane Daßler-Plenker, Johannes Brägelmann, Judith Müller, Andreas H. Scheel, Carina Lorenz, Richard Riedel, Adrianus J. de Langen, Miriam Bertrand, Dennis Plenker
Purpose: We sought to investigate the clinical response to MET inhibition in patients diagnosed with structural MET alterations and to characterize their functional relevance in cellular models.Experimental Design: Patients were selected for treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc2b8e2c6f4e840563f222c8458c3e6
https://doi.org/10.1158/1078-0432.c.6524654
https://doi.org/10.1158/1078-0432.c.6524654
Autor:
Shaun Stewart, Floris Fransen, Shane Harvey, Franziska Mortensen, Anita Stam, Rahel Awdew, Arpita Mondal, Christina Stevens, Eric Rovers, Steef Engels, Melissa Rentrop-Boeijen, Linda Hendriks, Brenda van Dieren, Rebecca Buonpane, Therese Visser, Pepijn Schellen, Ashwini Kulkarni, Jonathan Rios-Doria, Jing Zhou, Paul Tacken, Lu Lu, Vanessa Zondag-van der Zande, Cheng-Yen Huang, Renate den Blanken-Smit, John de Kruif, Rinse Klooster, Simon Plyte, Horacio Nastri, Patrick Mayes
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
François Rustenburg, Cyra E. Leurs, Bakhos A. Tannous, Maud Tjerkstra, Farrah J. Mateen, Sander Idema, Bauke Ylstra, W. Peter Vandertop, Laurine E. Wedekind, Nik Sol, Adrienne Vancura, Edward Post, William P.J. Leenders, R. Jonas A. Nilsson, B. Moraal, Jip Ramaker, Anna C. Navis, Kenn Zwaan, Ann Hoeben, Sjors G J G In 't Veld, Jihane Tannous, Joep Killestein, Philip C. De Witt Hamer, Jaap C. Reijneveld, Thomas Wurdinger, Heleen Verschueren, Pieter Wesseling, Pepijn Schellen, David P. Noske, Myron G. Best
Publikováno v:
Cell Reports Medicine, 1(7):100101. Cell Press
Cell reports. Medicine, 1(7):100101. Cell Press
Cell Reports Medicine, Vol 1, Iss 7, Pp 100101-(2020)
Cell Reports Medicine, 1, 7
Cell Reports. Medicine
Cell Reports Medicine, 1
Sol, N, in ‘t Veld, S G J G, Vancura, A, Tjerkstra, M, Leurs, C, Rustenburg, F, Schellen, P, Verschueren, H, Post, E, Zwaan, K, Ramaker, J, Wedekind, L E, Tannous, J, Ylstra, B, Killestein, J, Mateen, F, Idema, S, de Witt Hamer, P C, Navis, A C, Leenders, W P J, Hoeben, A, Moraal, B, Noske, D P, Vandertop, W P, Nilsson, R J A, Tannous, B A, Wesseling, P, Reijneveld, J C, Best, M G & Wurdinger, T 2020, ' Tumor-Educated Platelet RNA for the Detection and (Pseudo)progression Monitoring of Glioblastoma ', Cell reports. Medicine, vol. 1, no. 7, 100101, pp. 100101 . https://doi.org/10.1016/j.xcrm.2020.100101, https://doi.org/10.1016/j.xcrm.2020.100101
Cell reports. Medicine, 1(7):100101. Cell Press
Cell Reports Medicine, Vol 1, Iss 7, Pp 100101-(2020)
Cell Reports Medicine, 1, 7
Cell Reports. Medicine
Cell Reports Medicine, 1
Sol, N, in ‘t Veld, S G J G, Vancura, A, Tjerkstra, M, Leurs, C, Rustenburg, F, Schellen, P, Verschueren, H, Post, E, Zwaan, K, Ramaker, J, Wedekind, L E, Tannous, J, Ylstra, B, Killestein, J, Mateen, F, Idema, S, de Witt Hamer, P C, Navis, A C, Leenders, W P J, Hoeben, A, Moraal, B, Noske, D P, Vandertop, W P, Nilsson, R J A, Tannous, B A, Wesseling, P, Reijneveld, J C, Best, M G & Wurdinger, T 2020, ' Tumor-Educated Platelet RNA for the Detection and (Pseudo)progression Monitoring of Glioblastoma ', Cell reports. Medicine, vol. 1, no. 7, 100101, pp. 100101 . https://doi.org/10.1016/j.xcrm.2020.100101, https://doi.org/10.1016/j.xcrm.2020.100101
Summary Tumor-educated platelets (TEPs) are potential biomarkers for cancer diagnostics. We employ TEP-derived RNA panels, determined by swarm intelligence, to detect and monitor glioblastoma. We assessed specificity by comparing the spliced RNA prof
Autor:
Dennis Plenker, Erik Thunnissen, Pepijn Schellen, Judith Müller, Lukas C. Heukamp, Miriam Bertrand, Jürgen Wolf, Tobias Zacherle, Martin L. Sos, Carsten Kobe, Gunther Hartmann, Juliane Daßler-Plenker, Richard Riedel, Reinhard Büttner, Roopika Menon, Johannes M. Heuckmann, Frank Griesinger, Thomas Wurdinger, Carina Lorenz, Andreas H. Scheel, Johannes Brägelmann, Thorsten Persigehl, Adrianus J. de Langen, Alexander Kluge
Publikováno v:
Clinical Cancer Research, 24(6), 1337-1343. American Association for Cancer Research Inc.
Plenker, D, Bertrand, M, de Langen, A J, Riedel, R, Lorenz, C, Scheel, A H, Muller, J, Bragelmann, J, Daßler-Plenker, J, Kobe, C, Persigehl, T, Kluge, A, Wurdinger, T, Schellen, P, Hartmann, G, Zacherle, T, Menon, R, Thunnissen, E, Buttner, R, Griesinger, F, Wolf, J, Heukamp, L, Sos, M L & Heuckmann, J M 2018, ' Structural alterations of MET trigger response to MET kinase inhibition in lung adenocarcinoma patients ', Clinical Cancer Research, vol. 24, no. 6, pp. 1337-1343 . https://doi.org/10.1158/1078-0432.CCR-17-3001
Plenker, D, Bertrand, M, de Langen, A J, Riedel, R, Lorenz, C, Scheel, A H, Muller, J, Bragelmann, J, Daßler-Plenker, J, Kobe, C, Persigehl, T, Kluge, A, Wurdinger, T, Schellen, P, Hartmann, G, Zacherle, T, Menon, R, Thunnissen, E, Buttner, R, Griesinger, F, Wolf, J, Heukamp, L, Sos, M L & Heuckmann, J M 2018, ' Structural alterations of MET trigger response to MET kinase inhibition in lung adenocarcinoma patients ', Clinical Cancer Research, vol. 24, no. 6, pp. 1337-1343 . https://doi.org/10.1158/1078-0432.CCR-17-3001
Purpose: We sought to investigate the clinical response to MET inhibition in patients diagnosed with structural MET alterations and to characterize their functional relevance in cellular models. Experimental Design: Patients were selected for treatme
Autor:
Viola Caretti, Sophie E. M. Veldhuijzen van Zanten, Pieter Wesseling, Marianna Bugiani, Esther Hulleman, William P. Vandertop, Eleonora Aronica, Gertjan J.L. Kaspers, Dannis G. van Vuurden, Pepijn Schellen, David P. Noske
Publikováno v:
Oncotarget, 8, 60447-60452
Oncotarget, 8(36), 60447-60452. Impact Journals
Bugiani, M, van Zanten, S E M V, Caretti, V, Schellen, P, Aronica, E, Noske, D P, Vandertop, W P, Kaspers, G J L, van Vuurden, D G, Wesseling, P & Hulleman, E 2017, ' Deceptive morphologic and epigenetic heterogeneity in diffuse intrinsic pontine glioma ', Oncotarget, vol. 8, no. 36, pp. 60447-60452 . https://doi.org/10.18632/oncotarget.19726
Oncotarget
Oncotarget, 8, 36, pp. 60447-60452
Oncotarget, 8(36), 60447-60452. Impact Journals
Bugiani, M, van Zanten, S E M V, Caretti, V, Schellen, P, Aronica, E, Noske, D P, Vandertop, W P, Kaspers, G J L, van Vuurden, D G, Wesseling, P & Hulleman, E 2017, ' Deceptive morphologic and epigenetic heterogeneity in diffuse intrinsic pontine glioma ', Oncotarget, vol. 8, no. 36, pp. 60447-60452 . https://doi.org/10.18632/oncotarget.19726
Oncotarget
Oncotarget, 8, 36, pp. 60447-60452
// Marianna Bugiani 1, * , Sophie E.M. Veldhuijzen van Zanten 2, 3, * , Viola Caretti 4 , Pepijn Schellen 3 , Eleonora Aronica 5 , David P. Noske 3, 6 , William P. Vandertop 3, 7 , Gertjan J.L. Kaspers 2, 3, 8 , Dannis G. van Vuurden 2, 3 , Pieter We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246518d7891a24cc2b3e7b40341b0cfc
https://doi.org/10.18632/oncotarget.19726
https://doi.org/10.18632/oncotarget.19726
Autor:
Tonny Lagerweij, Anna C. Navis, Marc H. A. Jansen, Javad Nazarian, Hannes Vogel, Esther Hulleman, Thomas Wurdinger, Marianna Bugiani, David P. Noske, Pepijn Schellen, Ilona Horsman, Viola Caretti, Gertjan J.L. Kaspers, Pieter Wesseling, A. Charlotte P. Sewing, Michelle Monje, W. Peter Vandertop, Dannis G. van Vuurden
Publikováno v:
Acta Neuropathologica, 127, 897-909
Acta Neuropathologica, 127(6), 897-909. Springer Verlag
Caretti, V, Sewing, A C P, Lagerweij, T, Schellen, P, Bugiani, M, Jansen, M H A, van Vuurden, D G, Navis, A C, Horsman, I, Vandertop, W P, Noske, D P, Wesseling, P, Kaspers, G J, Nazarian, J, Vogel, H, Hulleman, E, Monje, M & Wurdinger, T 2014, ' Human pontine glioma cells can induce murine tumors ', Acta Neuropathologica, vol. 127, no. 6, pp. 897-909 . https://doi.org/10.1007/s00401-014-1272-4
Acta Neuropathologica, 127, 6, pp. 897-909
Acta neuropathologica, 127(6), 897-909. Springer Verlag
Acta Neuropathologica, 127(6), 897-909. Springer Verlag
Caretti, V, Sewing, A C P, Lagerweij, T, Schellen, P, Bugiani, M, Jansen, M H A, van Vuurden, D G, Navis, A C, Horsman, I, Vandertop, W P, Noske, D P, Wesseling, P, Kaspers, G J, Nazarian, J, Vogel, H, Hulleman, E, Monje, M & Wurdinger, T 2014, ' Human pontine glioma cells can induce murine tumors ', Acta Neuropathologica, vol. 127, no. 6, pp. 897-909 . https://doi.org/10.1007/s00401-014-1272-4
Acta Neuropathologica, 127, 6, pp. 897-909
Acta neuropathologica, 127(6), 897-909. Springer Verlag
Contains fulltext : 138191.pdf (Publisher’s version ) (Closed access) Diffuse intrinsic pontine glioma (DIPG), with a median survival of only 9 months, is the leading cause of pediatric brain cancer mortality. Dearth of tumor tissue for research ha
Autor:
Nik Sol, Jaap C. Reijneveld, Pepijn Schellen, Thomas Wurdinger, Henk Verheuk, Myron G. Best, Pieter Wesseling, François Rustenburg, Heleen Verschueren, Edward Post, Bakhos A. Tannous, Davis Noske, Bauke Ylstra, Sjors G J G In 't Veld, Jonas Nilsson
INTRODUCTION: Blood-based liquid biopsies are a potential approach for leveraging clinical cancer diagnostics and patients' treatment. However, so far, diagnostic, prognostic, predictive, and monitoring biomarkers for patients with diffuse glioma are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aeca12b2eeab92ef28b73cdaaa9b8f1
https://europepmc.org/articles/PMC4638720/
https://europepmc.org/articles/PMC4638720/
Autor:
Pieter Wesseling, Michelle Monje, Hannes Vogel, Gertjan J.L. Kaspers, Viola Caretti, Dannis G. van Vuurden, Pepijn Schellen, Marianna Bugiani, Marc H. A. Jansen, Paul G. Fisher, Esther Hulleman, Morgan E. Freret
Publikováno v:
Caretti, V, Bugiani, M, Freret, M, Schellen, P, Jansen, M H A, van Vuurden, D G, Kaspers, G, Fisher, P G, Hulleman, E, Wesseling, P, Vogel, H & Monje, M 2014, ' Subventricular spread of diffuse intrinsic pontine glioma ', Acta Neuropathologica, vol. 128, no. 4, pp. 605-607 . https://doi.org/10.1007/s00401-014-1307-x
Acta Neuropathologica, 128, 4, pp. 605-7
Acta Neuropathologica, 128, 605-7
Acta Neuropathologica, 128(4), 605-607. Springer Verlag
Acta Neuropathologica, 128, 4, pp. 605-7
Acta Neuropathologica, 128, 605-7
Acta Neuropathologica, 128(4), 605-607. Springer Verlag
Diffuse intrinsic pontine glioma (DIPG) is the second most common malignant pediatric brain tumor and the leading cause of brain tumor death in childhood [1]. 80 % of DIPG tumors exhibit a specific mutation (H3K27M) in the genes encoding histone 3.1
Autor:
Niki Karachaliou, Jihane Tannous, Thomas Wurdinger, Egbert F. Smit, Ana Giménez-Capitán, Santiago Viteri, R. Jonas A. Nilsson, Erik Thunnissen, Ana Drozdowskyj, Justine L. Kuiper, Bakhos A. Tannous, Pepijn Schellen, Daniëlle A.M. Heideman, Esther Drees, Magda Grabowska, Jordi Berenguer, Cristina Teixidó, Anne-Marie C. Dingemans, Rafael Rosell, Marte van Keulen
Publikováno v:
Oncotarget
Nilsson, R J A, Karachaliou, N, Berenguer, J, Gimenez-Capitan, A, Schellen, P, Teixido, C, Tannous, J, Kuiper, J L, Drees, E, Grabowska, M, van Keulen, M, Heideman, D A M, Thunnissen, E, Dingemans, A-M C, Viteri, S, Tannous, B A, Drozdowskyj, A, Rosell, R, Smit, E F & Wurdinger, T 2016, ' Rearranged EML4-ALK fusion transcripts sequester in circulating blood platelets and enable blood-based crizotinib response monitoring in non-small-cell lung cancer ', Oncotarget, vol. 7, no. 1, pp. 1066-1075 .
Oncotarget, 7(1), 1066-75. Impact Journals
Nilsson, R J A, Karachaliou, N, Berenguer, J, Gimenez-Capitan, A, Schellen, P, Teixido, C, Tannous, J, Kuiper, J L, Drees, E, Grabowska, M, van Keulen, M, Heideman, D A M, Thunnissen, E, Dingemans, A-M C, Viteri, S, Tannous, B A, Drozdowskyj, A, Rosell, R, Smit, E F & Wurdinger, T 2016, ' Rearranged EML4-ALK fusion transcripts sequester in circulating blood platelets and enable blood-based crizotinib response monitoring in non-small-cell lung cancer ', Oncotarget, vol. 7, no. 1, pp. 1066-75 . https://doi.org/10.18632/oncotarget.6279
Oncotarget, 7(1), 1066-1075. Impact Journals
Oncotarget, 7(1), 1066-1075. Impact Journals LLC
Nilsson, R J A, Karachaliou, N, Berenguer, J, Gimenez-Capitan, A, Schellen, P, Teixido, C, Tannous, J, Kuiper, J L, Drees, E, Grabowska, M, van Keulen, M, Heideman, D A M, Thunnissen, E, Dingemans, A-M C, Viteri, S, Tannous, B A, Drozdowskyj, A, Rosell, R, Smit, E F & Wurdinger, T 2016, ' Rearranged EML4-ALK fusion transcripts sequester in circulating blood platelets and enable blood-based crizotinib response monitoring in non-small-cell lung cancer ', Oncotarget, vol. 7, no. 1, pp. 1066-1075 .
Oncotarget, 7(1), 1066-75. Impact Journals
Nilsson, R J A, Karachaliou, N, Berenguer, J, Gimenez-Capitan, A, Schellen, P, Teixido, C, Tannous, J, Kuiper, J L, Drees, E, Grabowska, M, van Keulen, M, Heideman, D A M, Thunnissen, E, Dingemans, A-M C, Viteri, S, Tannous, B A, Drozdowskyj, A, Rosell, R, Smit, E F & Wurdinger, T 2016, ' Rearranged EML4-ALK fusion transcripts sequester in circulating blood platelets and enable blood-based crizotinib response monitoring in non-small-cell lung cancer ', Oncotarget, vol. 7, no. 1, pp. 1066-75 . https://doi.org/10.18632/oncotarget.6279
Oncotarget, 7(1), 1066-1075. Impact Journals
Oncotarget, 7(1), 1066-1075. Impact Journals LLC
// R. Jonas A. Nilsson 1,2,3,* , Niki Karachaliou 4,* , Jordi Berenguer 1 , Ana Gimenez-Capitan 5 , Pepijn Schellen 1,3 , Cristina Teixido 5 , Jihane Tannous 6 , Justine L. Kuiper 7 , Esther Drees 1 , Magda Grabowska 1 , Marte van Keulen 6 , Danielle