Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Pentti K. Siiteri"'
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 102:3739-3748
Context Full-term pregnancy is associated with a transient increase and life-time decrease in maternal breast cancer risk. Estrone (E1), estradiol (E2), and estriol (E3) are in high concentration during the third trimester. E1 and E2 metabolism produ
Autor:
Pentti K. Siiteri, Tamer M. Yalcinkaya, Geoffrey L. Hammond, Christine M. Drea, Caroline Underhill, Solange Miguel-Queralt, Aaron P. Wagner, Stephen E. Glickman, Ned J. Place
Publikováno v:
Endocrinology. 153:1435-1443
Exposures to sex steroids during fetal development are thought to contribute to the unique urogenital anatomy and social dominance of the female spotted hyena: overt phenotypes not shared by other hyenids (i.e. striped hyena, brown hyena, and aardwol
Autor:
Bill L. Lasley, Pentti K. Siiteri, Richard G. Stevens, Barbara A. Cohn, Richard D. Cohen, Mary Beth Terry
Publikováno v:
Alcohol. 36:47-53
Factors that change sex hormone levels during pregnancy may have long-term health consequences for the offspring, including changes in breast cancer risk. A cross-sectional analysis of alcohol consumption and hormone levels in 339 pregnant women samp
Autor:
Rebecca Troisi, William R. Crombleholme, James M. Roberts, Robert N. Hoover, Pentti K. Siiteri, Roberta B. Ness, Nancy Potischman, David L. Lykins
Publikováno v:
International Journal of Epidemiology. 32:455-460
Epidemiological studies show a substantially reduced risk of breast cancer in adult daughters of preeclamptic pregnancies, and modest risk reductions have been demonstrated for mothers also. Alterations in pregnancy hormone concentrations, particular
Autor:
Geoffrey L. Hammond, Jaya Natarajan, Pentti K. Siiteri, George W. Creasy, Larry S. Abrams, J.Glyn Allen
Publikováno v:
Contraception. 67:93-99
Norelgestromin (NGMN) and levonorgestrel (LNG) are the main active metabolites of norgestimate (NGM), but their relative contributions to the pharmacological effects of NGM are unclear. We have therefore determined the serum distribution of these NGM
Publikováno v:
American Journal of Epidemiology. 146:476-482
Elevated insulin levels may explain part of the increased risk of endometrial cancer observed in obese postmenopausal women. Circulating sex hormones and fasting C-peptide levels were measured in sera obtained from 165 postmenopausal endometrial canc
Autor:
Jimmie B. Vaught, S C Rossi, P Kiuru, Thomas R. Fears, D Sepkovic, Jennifer L. Donaldson, H L Bradlow, Roni T. Falk, M H Gail, Robert N. Hoover, K Wahala, Herman Adlercreutz, Regina G. Ziegler, Capri-Mara Fillmore, Pentti K. Siiteri
Publikováno v:
Environmental Health Perspectives
Rapid and simple enzyme immunoassays (EIAs) were recently developed to measure 2-hydroxyestrone and 16alpha-hydroxyestrone in unextracted urine. The balance between these competing estrogen metabolism pathways may serve as a biomarker of breast cance
Autor:
Pamela L. Horn-Ross, Anna H. Wu, Laurence N. Kolonel, Regina G. Ziegler, Pentti K. Siiteri, Robert N. Hoover, Dee W. West, Malcolm C. Pike, Joseph F. Fraumeni, Abraham M. Y. Nomura, Andrew J. Lake
Publikováno v:
JNCI Journal of the National Cancer Institute. 88:650-660
Background : Breast cancer incidence rates have historically been four to seven times higher in the United States than in China or Japan, although the reasons remain elusive. When Chinese, Japanese, or Filipino women migrate to the United States, the
Publikováno v:
Journal of Chromatography A. 690:149-154
Capillary electrophoresis of the sex hormone estrogens using different buffer components was investigated. Free zone electrophoresis with 10 mM phosphate buffer (pH 11.5) or 10 mM phosphate buffer with 10-20% methanol was not effective in separating
Publikováno v:
Endocrinology. 133:368-375
Both cortisol and aldosterone bind to and activate the mineralocorticoid receptor. Cortisol concentrations are generally 100- to 200-fold higher than aldosterone concentrations, yet mineralocorticoids clearly exert effects different from glucocortico