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Akademický článek
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Autor:
Andrew Crowe, Penny Wong
Publikováno v:
Drug Development and Industrial Pharmacy. 30:449-459
Loperamide is a peripherally acting antidiarrheal opioid with some affinity for P-glycoprotein (P-gp). One of the main reasons for its lack of central nervous system (CNS) activity is a combination first-pass metabolism and P-gp-mediated efflux preve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56da3d9fa7b4211e008861767e1b5e9b
https://doi.org/10.1081/ddc-120037471
https://doi.org/10.1081/ddc-120037471
Autor:
Penny Wong, Andrew Crowe
Publikováno v:
Toxicology and applied pharmacology. 193(1)
This study examined the accumulation and transport of two related systemic opioids used as antidiarrhoeal drugs and compared their rates of transport with known P-glycoprotein (P-gp) substrates used in our in vitro environment. Cellular uptake and ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0414069186c90c7a470531928f36c893
https://pubmed.ncbi.nlm.nih.gov/14613723
https://pubmed.ncbi.nlm.nih.gov/14613723
Autor:
Greene, Angie, Pycroft, Chris, Jagose, Annamarie, Raskopoulos, Jordan, Phelps, Kerryn, Penny Wong
Publikováno v:
Cosmopolitan (Australia Edition); Mar2017, p109-123, 15p, 19 Color Photographs, 34 Black and White Photographs