Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Penny S. Thomas"'
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
Tgfb3 is strongly and specifically expressed in the epithelial tips of pre-fusion palatal shelves where it plays a critical non-redundant role in palatal fusion in both medial edge epithelial (MEE) cells and in a thin layer of flattened peridermal ce
Externí odkaz:
https://doaj.org/article/2caa70ca62a04a55bd235dd4f09b8a30
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35539 (2012)
Bicuspid aortic valve (BAV) is the most common congenital cardiac anomaly in humans. Despite recent advances, the molecular basis of BAV development is poorly understood. Previously it has been shown that mutations in the Notch1 gene lead to BAV and
Externí odkaz:
https://doaj.org/article/323f423bf0654aeb8b5db476e6d98d13
Autor:
Jieun Kim, Qianfeng Li, Penny S. Thomas, Vesa Kaartinen, Brian A. Pierchala, Liang tung Yang, Emil Bogenmann
Publikováno v:
genesis. 49:862-869
The p75(NTR) neurotrophin receptor has been implicated in multiple biological and pathological processes. While significant advances have recently been made in understanding the physiologic role of p75(NTR) , many details and aspects remain to be det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c9aad1b9b2a035d5ecf73c51c228e0
https://doi.org/10.1002/dvg.20747
https://doi.org/10.1002/dvg.20747
Publikováno v:
Developmental Dynamics. 237:692-701
In the developing heart, reciprocal interactions between the epicardium and myocardium drive further sublineage specification and ventricular chamber morphogenesis. Several observations suggest that the epicardium is a source of secreted factors that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d897e2d0da49a2fa481ac70f346f7366
https://doi.org/10.1002/dvdy.21469
https://doi.org/10.1002/dvdy.21469
Autor:
Eleftherios Sachlos, Penny S. Thomas, Jan T. Czernuszka, Sally A. Dreger, Patricia M. Taylor, Adrian H. Chester, Magdi H. Yacoub
Publikováno v:
Tissue Engineering. 12:2533-2540
Matrix remodeling, which involves proteolytic enzymes, such as the matrix metalloproteinases (MMPs), is of significant importance with respect to tissue engineering a heart valve construct. The ability of valve interstitial cells (ICs) to release the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45f84ff4699f40ec13219a1861b8b64
https://doi.org/10.1089/ten.2006.12.2533
https://doi.org/10.1089/ten.2006.12.2533
This book is concerned with basic molecular biology and how research in this field relates to our understanding of molecular and cellular aspects of cardiac development and growth. The authors point out that molecular biology has provided a wealth of
Publikováno v:
International Journal of Bifurcation and Chaos. 13:3665-3674
The anatomy of the atrioventricular conduction system was first described nearly a hundred years ago. Since then, it has been an occasional subject of controversy mainly through a lack of adherence to the original definitions based on histology. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::041d359af0cdf63a7806a33950b6f908
https://doi.org/10.1142/s0218127403008879
https://doi.org/10.1142/s0218127403008879
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 35:113-118
Cardiac valve interstitial cells (ICs) are a heterogeneous and dynamic population of specific cell types that have many unique characteristics. They are responsible for maintaining the extracellular scaffold that provides the mechanical characteristi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0e9ff135339094097b270667670b1f
https://doi.org/10.1016/s1357-2725(02)00100-0
https://doi.org/10.1016/s1357-2725(02)00100-0
Autor:
Yuji Mishina, Mamoru Ishii, Jun Ninomiya-Tsuji, Kenji Yumoto, Maiko Inagaki, Jamie Lane, Robert E. Maxson, Gregory J. Scott, Kouichi Matsuzaki, Manas K. Ray, Penny S. Thomas, Vesa Kaartinen
Publikováno v:
The Journal of biological chemistry. 288(19)
The role of Smad-independent TGF-β signaling in craniofacial development is poorly elucidated.In craniofacial mesenchymal cells, Tak1 regulates both R-Smad C-terminal and linker region phosphorylation in TGF-β signaling.Tak1 plays an irreplaceable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496a454587a0226b8b9667c0c61a7e64
https://pubmed.ncbi.nlm.nih.gov/23546880
https://pubmed.ncbi.nlm.nih.gov/23546880
The small GTP-binding protein Rac1, a member of the Rho family of small GTPases, has been implicated in regulation of many cellular processes including adhesion, migration and cytokinesis. These functions have largely been attributed to its ability t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2111f2abd0112a891f85178da8847a29
https://europepmc.org/articles/PMC2854286/
https://europepmc.org/articles/PMC2854286/