Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Penny L Groves"'
Autor:
Julie G Burel, Simon H Apte, Penny L Groves, Kerenaftali Klein, James S McCarthy, Denise L Doolan
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005839 (2016)
Using a unique resource of samples from a controlled human malaria infection (CHMI) study, we identified a novel population of CD4+ T cells whose frequency in the peripheral blood was inversely correlated with parasite burden following P. falciparum
Externí odkaz:
https://doaj.org/article/6863119f7e5b41faa8f185cfd33839e3
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77811 (2013)
The pre-erythrocytic stages of Plasmodium spp. are increasingly recognised as ideal targets for prophylactic vaccines and drug treatments. Intense research efforts in the last decade have been focused on in vitro culture and in vivo detection and qua
Externí odkaz:
https://doaj.org/article/adc9ae7a46ac4e53b4a7b0ef11d3354b
Autor:
Simon H Apte, Penny L Groves, Mariusz Skwarczynski, Yoshio Fujita, Chenghung Chang, Istvan Toth, Denise L Doolan
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e40928 (2012)
Vaccines against many pathogens for which conventional approaches have failed remain an unmet public health priority. Synthetic peptide-based vaccines offer an attractive alternative to whole protein and whole organism vaccines, particularly for comp
Externí odkaz:
https://doaj.org/article/0659628ac1f34a1c95ab2a75a4fdc082
Autor:
Jessica, Poole, Lauren E, Hartley-Tassell, Christopher J, Day, Danielle I, Stanisic, Penny L, Groves, Sumana, Chakravarty, B Kim, Lee Sim, Stephen L, Hoffman, Joe, Tiralongo, Nicolai, Bovin, Denise L, Doolan, Michael P, Jennings
Publikováno v:
ACS infectious diseases. 7(8)
The transmission of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::89403032f2746a0e77df127d7a94fb6e
https://pubmed.ncbi.nlm.nih.gov/34170120
https://pubmed.ncbi.nlm.nih.gov/34170120
Autor:
Simon H. Apte, David J. Pattinson, Penny L. Groves, Anton P. J. Middelberg, Denise L. Doolan, Tania Rivera-Hernandez, Nani Wibowo
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Despite extensive research, the development of an effective malaria vaccine remains elusive. The induction of robust and sustained T cell and antibody response by vaccination is an urgent unmet need. Chimeric virus-like particles (VLPs) are a promisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0444f14a415af94aec3af03e1199cf30
https://www.frontiersin.org/article/10.3389/fimmu.2020.564627/full
https://www.frontiersin.org/article/10.3389/fimmu.2020.564627/full
Autor:
Simon H, Apte, Gabriela, Minigo, Penny L, Groves, Jessie C, Spargo, Magdalena, Plebanski, Mathew J, Grigg, Enny, Kenangalem, Julie G, Burel, Jessica R, Loughland, Katie L, Flanagan, Kim A, Piera, Timothy, William, Ric N, Price, Tonia, Woodberry, Bridget E, Barber, Nicholas M, Anstey, Denise L, Doolan
Publikováno v:
Clinical & Translational Immunology
Objective CD4+ T cells are critical mediators of immunity to Plasmodium spp. infection, but their characteristics during malarial episodes and immunopathology in naturally infected adults are poorly defined. Flow cytometric analysis of PBMCs from pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e468ad774d443bdf7bf89a91e141eee
https://pubmed.ncbi.nlm.nih.gov/33282291
https://pubmed.ncbi.nlm.nih.gov/33282291
Autor:
Penny L. Groves, Virginia McPhun, Sumana Chakravarty, Denise L. Doolan, Amber I. Raja, Michael F. Good, Yeping Cai, Stephen L. Hoffman, Jennifer M. Reiman, Ian A. Cockburn, Danielle I. Stanisic
Publikováno v:
Infection and Immunity
The development of a vaccine is essential for the elimination of malaria. However, despite many years of effort, a successful vaccine has not been achieved. Most subunit vaccine candidates tested in clinical trials have provided limited efficacy, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992eaf3b7986839e1dd5d9565563b305
http://europepmc.org/articles/PMC4962623
http://europepmc.org/articles/PMC4962623
Autor:
Rebeca Santano, Tamara Katherine Berthoud, Alfons Jiménez, Llorenç Quintó, Caterina Guinovart, Pedro L. Alonso, Maria N. Manaca, John J. Aponte, Ruth Aguilar, Arnoldo Barbosa, Carlota Dobaño, Denise L. Doolan, Penny L Groves, Quique Bassat, Augusto Nhabomba, Mauricio H. Rodríguez
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Clin Infect Dis
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Clin Infect Dis
Background The effect of timing of exposure to first Plasmodium falciparum infections during early childhood on the induction of innate and adaptive cytokine responses and their contribution to the development of clinical malaria immunity is not well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fffa4888dce168ace581808079dce8f4
http://hdl.handle.net/2445/128982
http://hdl.handle.net/2445/128982
Autor:
Penny L. Groves, Andrew M. Redmond, Sophie Schussek, Denise L. Doolan, Simon H. Apte, David J. Pattinson
Publikováno v:
European Journal of Immunology. 43:2707-2717
CD103⁺ dermal dendritic cells (dDCs) are a recently described DC subset of the skin shown to be the principal migratory DCs capable of efficiently cross-presenting antigens and activating CD8⁺ T cells. Harnessing their activity would promote vacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24642766afec69ab99382b380a1972a4
https://doi.org/10.1002/eji.201343475
https://doi.org/10.1002/eji.201343475
Autor:
Istvan Toth, Penny L. Groves, Salwa Aljohani, Sharareh Eskandari, Pavla Simerska, Rachel J. Stephenson, Simon H. Apte, Denise L. Doolan
Publikováno v:
Nanomedicine (London, England). 11(2)
Aim: Systematically evaluate lipid core peptide vaccine delivery platforms to identify core features promoting strong CD8+ T-cell responses. Materials & methods: Three different self-adjuvanting lipid core peptide nanovaccines each comprising four co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811f64d50313278d8f2afb7ade2c8434
https://pubmed.ncbi.nlm.nih.gov/26653407
https://pubmed.ncbi.nlm.nih.gov/26653407