Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Penny Groves"'
Autor:
Carlota Dobaño, Tamara Berthoud, Maria Nelia Manaca, Augusto Nhabomba, Caterina Guinovart, Ruth Aguilar, Arnoldo Barbosa, Penny Groves, Mauricio H. Rodríguez, Alfons Jimenez, Lazaro M. Quimice, John J. Aponte, Jaume Ordi, Denise L. Doolan, Alfredo Mayor, Pedro L. Alonso
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-13 (2018)
Abstract Background Increased susceptibility to malaria during pregnancy is not completely understood. Cellular immune responses mediate both pathology and immunity but the effector responses involved in these processes have not been fully characteri
Externí odkaz:
https://doaj.org/article/6068edda8d864588ba8ef3f5f67f130d
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27666 (2011)
BackgroundVaccine development against malaria and other complex diseases remains a challenge for the scientific community. The recent elucidation of the genome, proteome and transcriptome of many of these complex pathogens provides the basis for rati
Externí odkaz:
https://doaj.org/article/3d934c405da34b8a9af8fe2efbba4415
Autor:
Sumana Chakravarty, Penny Groves, Denise L. Doolan, Lauren E. Hartley-Tassell, Nicolai V. Bovin, Michael P. Jennings, Christopher J. Day, B. Kim Lee Sim, Joe Tiralongo, Stephen L. Hoffman, Danielle I. Stanisic, Jessica Poole
Publikováno v:
ACS Infectious Diseases. 7:2383-2389
The transmission of Plasmodium spp. sporozoites to the mammalian host is the first step in the initiation of the mosquito-borne disease known as malaria. The exact route of transmission from the bloodstream to the liver is still not clearly elucidate
Autor:
Karina Pires de Sousa, Denise L. Doolan, Penny Groves, Jason Mulvenna, Alex Loukas, Javier Sotillo, Jeremy Potriquet, Simon H. Apte
Publikováno v:
International journal for parasitology. 52(1)
Small extracellular vesicles, including exosomes, are formed by the endocytic pathway and contain genetic and protein material which reflect the contents of their cells of origin. These contents have a role in vesicle-mediated information transfer, a
Autor:
Simon H. Apte, Yap P. Chuan, David J. Pattinson, Penny Groves, Anton P. J. Middelberg, Linda H.L. Lua, Tania Rivera-Hernandez, Nani Wibowo, Denise L. Doolan
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
An effective vaccine against the Plasmodium parasite is likely to require the induction of robust antibody and T cell responses. Chimeric virus-like particles are an effective vaccine platform for induction of antibody responses, but their capacity t
Autor:
Michael J. Smout, Phurpa Wangchuk, Simon H. Apte, Penny Groves, Denise L. Doolan, Alex Loukas
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3490 (2018)
International Journal of Molecular Sciences
Volume 19
Issue 11
International Journal of Molecular Sciences
Volume 19
Issue 11
Plant-derived compounds that modulate the immune responses are emerging as frontline treatment agents for cancer, infectious diseases and autoimmunity. Herein we have isolated 40 phytochemicals from five Bhutanese Sowa Rigpa medicinal plants&mdash
Publikováno v:
European Journal of Immunology. 46:863-873
While the functional plasticity of memory CD4(+) T cells has been studied extensively, less is known about this property in memory CD8(+) T cells. Here, we report the direct measurement of plasticity by paired daughter analysis of effector and memory
Autor:
Tamara Katherine Berthoud, Carlota Dobaño, Jaume Ordi, Augusto Nhabomba, Arnoldo Barbosa, Ruth Aguilar, Maria N. Manaca, Pedro L. Alonso, John J. Aponte, Denise L. Doolan, Mauricio H. Rodríguez, Alfons Jiménez, Penny Groves, Caterina Guinovart, Alfredo Mayor, Lazaro M. Quimice
Publikováno v:
Malaria Journal
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Malaria Journal, Vol 17, Iss 1, Pp 1-13 (2018)
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Malaria Journal, Vol 17, Iss 1, Pp 1-13 (2018)
BACKGROUND: Increased susceptibility to malaria during pregnancy is not completely understood. Cellular immune responses mediate both pathology and immunity but the effector responses involved in these processes have not been fully characterized. Mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755c9320a1a5692476d91a35612a96eb
http://hdl.handle.net/2445/122760
http://hdl.handle.net/2445/122760
Autor:
Rachel J. Stephenson, Bita Sedaghat, Simon H. Apte, Istvan Toth, Denise L. Doolan, Saranya Chandurudu, David J. Pattinson, Penny Groves, Sharareh Eskandari
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 24(39)
Adjuvant development and understanding the physicochemical properties of particles and interpreting the subsequent immunological responses is a challenge faced by many researchers in the vaccine field. We synthesized and investigated the physicochemi
Autor:
Christine Langer, Julie G. Burel, Michelle J. Boyle, Denise L. Doolan, James S. McCarthy, Penny Groves, Simon H. Apte, James G. Beeson
Publikováno v:
JCI Insight. 2
Clinical responses to infection or vaccination and the development of effective immunity are characterized in humans by a marked interindividual variability. To gain an insight into the factors affecting this variability, we used a controlled human i