Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Penny B. Svetlik"'
Autor:
Warner C. Greene, Penny B. Svetlik, Richard D. Klausner, Warren L. Leonard, Thomas A. Waldmann, Allan M. Weissman, Joel M. Depper, Joe B. Harford
Publikováno v:
Proceedings of the National Academy of Sciences. 83:1463-1466
Interleukin 2 (IL-2) receptors are expressed on activated T cells and in select T-cell leukemias. Recently, it has been demonstrated that at least two classes of receptor for IL-2 exist with markedly different affinities for ligand. All known biologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb17db20c1e3463fc759b0dd3f6c9b3e
https://doi.org/10.1073/pnas.83.5.1463
https://doi.org/10.1073/pnas.83.5.1463
Autor:
Warren J. Leonard, Cynthia M. Rusk, Penny B. Svetlik, Richard J. Robb, Warner C. Greene, Joel M. Depper
Publikováno v:
The Journal of Experimental Medicine
Human interleukin 2 (IL-2) receptor cDNA derived from HUT 102B2 cells was stably expressed in murine L cells. These L cell transfectants (a) displayed surface receptors of the aberrant size of the IL-2 receptors on HUT 102B2 cells, (b) did not respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::836f6a9a8c43df7f86048140c496cd9f
https://doi.org/10.1084/jem.162.1.363
https://doi.org/10.1084/jem.162.1.363
Autor:
Janet Pumphrey, Warren J. Leonard, Gerald R. Crabtree, Martin Krönke, Richard J. Robb, Thomas A. Waldmann, Penny B. Svetlik, Stuart Rudikoff, Nancy J. Peffer, Warner C. Greene, Joel M. Depper
Publikováno v:
Immune Regulation ISBN: 9781461293903
We have identified cDNAs encoding the human interleu- kin-2 (IL-2) receptor from a cDNA library constructed from HUT-102B2 cell mRNA, and have expressed them in eukaryotic cells. Based on the deduced amino acid sequence from the DNA sequence, the IL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff9c6842165b20acdc5fa6e5d5ee5525
https://doi.org/10.1007/978-1-4612-4996-2_24
https://doi.org/10.1007/978-1-4612-4996-2_24
Autor:
Warner C. Greene, Warren J. Leonard, Gerald R. Crabtree, Richard J. Robb, Penny B. Svetlik, Janet Pumphrey, Martin Krönke, Stuart Rudikoff, Joel M. Depper, Thomas A. Waldmann, Nancy J. Peffer
Publikováno v:
Lymphoproliferative Diseases: Pathogenesis, Diagnosis, Therapy ISBN: 9789401087216
Complete expression of the human immune response requires the generation of activated T cells1. This activation sequence is initiated by an interaction of antigen with specific receptors present on the membrane of resting T cells. This receptor-ligan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4efb439396262e20aebbcb8dc0508be
https://doi.org/10.1007/978-94-009-5016-0_2
https://doi.org/10.1007/978-94-009-5016-0_2
Autor:
Warren J. Leonard, M Krönke, Janet Pumphrey, Thomas A. Waldmann, Nancy J. Peffer, Richard J. Robb, Gerald R. Crabtree, Warner C. Greene, Stuart Rudikoff, Penny B. Svetlik, Joel M. Depper
Publikováno v:
Modern Trends in Human Leukemia VI New Results in Clinical and Biological Research Including Pediatric Oncology ISBN: 9783540153290
Interleukin-2 (IL-2 or T cell growth factor) is a 14,500 daltons glycoprotein critically involved in the development of a normal human immune response [1, 2]. Recently, cDNA for this lymphokine has been isolated and expressed in both prokaryotic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00a6c4dd5d48ceb71af6c87610043934
https://doi.org/10.1007/978-3-642-70385-0_80
https://doi.org/10.1007/978-3-642-70385-0_80
Autor:
William A. Haseltine, Joseph Sodroski, Warren J. Leonard, Penny B. Svetlik, Craig A. Rosen, Yuji Wano, Warner C. Greene, Wei Chun Goh, Nancy J. Peffer
Publikováno v:
Science (New York, N.Y.). 232(4752)
The human T-lymphotropic viruses types I and II (HTLV-I and -II) have been etiologically linked with certain T-cell leukemias and lymphomas that characteristically display membrane receptors for interleukin-2. The relation of these viruses to this gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f078dfb8aba68ccb1f142d8933fa90f4
https://pubmed.ncbi.nlm.nih.gov/3010456
https://pubmed.ncbi.nlm.nih.gov/3010456
Autor:
Warner C. Greene, Warren J. Leonard, Margery Sullivan, Joel M. Depper, Martin Krönke, Minoru Kanehisa, Nancy J. Peffer, Penny B. Svetlik
Publikováno v:
Science (New York, N.Y.). 230(4726)
The gene encoding the human interleukin-2 (IL-2) receptor consists of 8 exons spanning more than 25 kilobases on chromosome 10. Exons 2 and 4 were derived from a gene duplication event and unexpectedly also are homologous to the recognition domain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e3af639126f8d4e390f739b2088ffd
https://pubmed.ncbi.nlm.nih.gov/2996141
https://pubmed.ncbi.nlm.nih.gov/2996141
Autor:
Warren J. Leonard, Janet Pumphrey, Martin Krönke, Richard J. Robb, Penny B. Svetlik, Warner C. Greene, Gerald R. Crabtree, Thomas A. Waldmann, Stuart Rudikoff, Joel M. Depper, Nancy J. Peffer
Publikováno v:
Nature. 311(5987)
We have purified the human T-cell growth factor (interleukin-2) receptor and have cloned, sequenced and expressed cDNAs corresponding to this receptor. We identify one gene, but two interleukin-2 receptor mRNAs which differ in their polyadenylation s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6251fa4fc7ed1b96f76e49f06c492c9a
https://pubmed.ncbi.nlm.nih.gov/6090948
https://pubmed.ncbi.nlm.nih.gov/6090948
Autor:
Joseph Sodroski, Warren J. Leonard, Craig A. Rosen, William A. Haseltine, Warner C. Greene, Penny B. Svetlik, Yuji Wano, Wei Chun Goh, Nancy J. Peffer
Publikováno v:
Science (New York, N.Y.). 235(4792)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99ef9126a25fc3704b3f564c193550c
https://pubmed.ncbi.nlm.nih.gov/3029865
https://pubmed.ncbi.nlm.nih.gov/3029865
Autor:
Marc Feldmann, N. A. Mitchison
Leukocyte culture conferences have a long pedigree. This volume records some of the scientific highlights of the 16th such annual con ference, and is a witness to the continuing evolution and popularity of leukocyte culture and of immunology. There