Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors.

Autor: Singh B; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Bernatchez JA; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California 92093, United States., McCall LI; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California 92093, United States., Calvet CM; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California 92093, United States., Ackermann J; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California 92093, United States., Souza JM; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California 92093, United States., Thomas D; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California 92093, United States., Silva EM; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California 92093, United States., Bachovchin KA; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Klug DM; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Jalani HB; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Bag S; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Buskes MJ; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Leed SE; Experimental Therapeutics, Walter Reed Army Institute of Research, 2460 Linden Lane, Silver Spring, Maryland 20910, United States., Roncal NE; Experimental Therapeutics, Walter Reed Army Institute of Research, 2460 Linden Lane, Silver Spring, Maryland 20910, United States., Penn EC; Experimental Therapeutics, Walter Reed Army Institute of Research, 2460 Linden Lane, Silver Spring, Maryland 20910, United States., Erath J; Department of Microbiology, New York University School of Medicine, 430 East 29th Street, New York, New York 10010, United States., Rodriguez A; Department of Microbiology, New York University School of Medicine, 430 East 29th Street, New York, New York 10010, United States., Sciotti RJ; Experimental Therapeutics, Walter Reed Army Institute of Research, 2460 Linden Lane, Silver Spring, Maryland 20910, United States., Campbell RF; Experimental Therapeutics, Walter Reed Army Institute of Research, 2460 Linden Lane, Silver Spring, Maryland 20910, United States., McKerrow J; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California 92093, United States., Siqueira-Neto JL; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California 92093, United States., Ferrins L; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States., Pollastri MP; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2020 Jan 10; Vol. 11 (3), pp. 249-257. Date of Electronic Publication: 2020 Jan 10 (Print Publication: 2020).