Výsledky vyhledávání - "Penington A, J"

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Analysis of pacemaker activity in a two-component model of some brainstem neurons

Autor: Tuckwell, Henry C., Zhou, Ying, Penington, Nicholas J.

Serotonergic, noradrenergic and dopaminergic brainstem (including midbrain) neurons, often exhibit spontaneous and fairly regular spiking with frequencies of order a few Hz, though dopaminergic and noradrenergic neurons only exhibit such pacemaker-ty

Externí odkaz: http://arxiv.org/abs/1704.03941

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Simplified models of pacemaker spiking in raphe and locus coeruleus neurons

Autor: Tuckwell, Henry C., Zhou, Ying, Penington, Nicholas J.

Many central neurons, and in particular certain brainstem aminergic neurons exhibit spontaneous and fairly regular spiking with frequencies of order a few Hz. A large number of ion channel types contribute to such spiking so that accurate modeling of

Externí odkaz: http://arxiv.org/abs/1508.05468

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Computational modeling of spike generation in serotonergic neurons of the dorsal raphe nucleu

Autor: Tuckwell, Henry C., Penington, Nicholas J.

We consider here a single-compartment model of these neurons which is capable of describing many of the known features of spike generation, particularly the slow rhythmic pacemaking activity often observed in these cells in a variety of species. Incl

Externí odkaz: http://arxiv.org/abs/1212.1096

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Properties of IA in a serotonergic neuron of the dorsal raphe nucleus

Autor: Penington, Nicholas J, Tuckwell, Henry C

Voltage clamp data were analyzed in order to characterize the properties of the fast potassium transient current IA for a serotonergic neuron of the rat dorsal raphe nucleus (DRN). We obtain maximal conductance, time constants of activation and inact

Externí odkaz: http://arxiv.org/abs/1107.3450

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