Pharmacokinetics and Safety of Intramuscular Injectable Benzathine Penicillin G in Japanese Healthy Participants.

Autor: Li Y; Pfizer R&D, Tokyo, Japan., Okayama A; Pfizer R&D, Tokyo, Japan., Hagi T; Pfizer R&D, Tokyo, Japan., Muto C; Pfizer R&D, Tokyo, Japan., Raber S; Pfizer Inc., San Diego, CA, USA., Nagashima M; Pfizer R&D, Tokyo, Japan.

Publikováno v: Journal of clinical pharmacology [J Clin Pharmacol] 2024 Oct; Vol. 64 (10), pp. 1259-1266. Date of Electronic Publication: 2024 May 12.

"Hurts less, lasts longer"; a qualitative study on experiences of young people receiving high-dose subcutaneous injections of benzathine penicillin G to prevent rheumatic heart disease in New Zealand.

Autor: Cooper J; Department of Public Health, University of Otago, Wellington, New Zealand., Enkel SL; Telethon Kids Institute, Nedlands, Western Australia, Australia., Moodley D; Department of Public Health, University of Otago, Wellington, New Zealand., Dobinson H; Te Whatu Ora, Capital, Coast and Hutt Valley, Newtown, Wellington, New Zealand., Andersen E; Te Whatu Ora, Capital, Coast and Hutt Valley, Newtown, Wellington, New Zealand., Kado JH; Telethon Kids Institute, Nedlands, Western Australia, Australia.; Centre for Child Health Research, The University of Western Australia, Crawley, WA, Australia., Barr RK; Telethon Kids Institute, Nedlands, Western Australia, Australia., Salman S; Telethon Kids Institute, Nedlands, Western Australia, Australia.; Clinical Pharmacology and Toxicology Unit, PathWest, Perth, Western Australia, Australia.; Internal Medicine, The University of Western Australia, Crawley, WA, Australia., Baker MG; Department of Public Health, University of Otago, Wellington, New Zealand., Carapetis JR; Telethon Kids Institute, Nedlands, Western Australia, Australia.; Perth Children's Hospital, Nedlands, Western Australia, Australia.; Centre for Child Health Research, The University of Western Australia, Crawley, WA, Australia., Manning L; Telethon Kids Institute, Nedlands, Western Australia, Australia.; Internal Medicine, The University of Western Australia, Crawley, WA, Australia.; Centre for Child Health Research, The University of Western Australia, Crawley, WA, Australia.; Fiona Stanley Hospital, Nedlands, Western Australia, Australia., Anderson A; Faculty of Medical and Health Sciences, Te Kupenga Hauora Māori, University of Auckland, Auckland, New Zealand., Bennett J; Department of Public Health, University of Otago, Wellington, New Zealand.

Publikováno v: PloS one [PLoS One] 2024 May 14; Vol. 19 (5), pp. e0302493. Date of Electronic Publication: 2024 May 14 (Print Publication: 2024).

Oral linezolid compared with benzathine penicillin G for treatment of early syphilis in adults (Trep-AB Study) in Spain: a prospective, open-label, non-inferiority, randomised controlled trial.

Autor: Ubals M; Skin Neglected Tropical Diseases and Sexually Transmitted Infections Section, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; Facultat de Medicina, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain; Dermatology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Nadal-Baron P; Facultat de Medicina, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain; Microbiology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Arando M; Infectious Diseases Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Rivero Á; Fundació Lluita Contra les Infeccions, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; Barcelona Checkpoint, Projecte dels NOMS, Hispanosida, Barcelona., Mendoza A; Skin Neglected Tropical Diseases and Sexually Transmitted Infections Section, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; Fundació Lluita Contra les Infeccions, Hospital Universitari Germans Trias i Pujol, Badalona, Spain., Descalzo Jorro V; Infectious Diseases Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Ouchi D; Fundació Lluita Contra les Infeccions, Hospital Universitari Germans Trias i Pujol, Badalona, Spain., Pérez-Mañá C; Clinical Pharmacology Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain., Álvarez M; Pharmacy Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain., Alemany A; Skin Neglected Tropical Diseases and Sexually Transmitted Infections Section, Hospital Universitari Germans Trias i Pujol, Badalona, Spain., Hoyos-Mallecot Y; Microbiology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Nunley E; Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, WA, USA., Lieberman NAP; Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, WA, USA., Greninger AL; Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, WA, USA; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Galván-Casas C; Fundació Lluita Contra les Infeccions, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; Hospital Universitario de Mostoles, Madrid, Spain., Suñer C; Skin Neglected Tropical Diseases and Sexually Transmitted Infections Section, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; Fundació Lluita Contra les Infeccions, Hospital Universitari Germans Trias i Pujol, Badalona, Spain., G-Beiras C; Skin Neglected Tropical Diseases and Sexually Transmitted Infections Section, Hospital Universitari Germans Trias i Pujol, Badalona, Spain., Paredes R; Fundació Lluita Contra les Infeccions, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; Department of Infectious Diseases, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; IrsiCaixa AIDS Research Institute, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; CIBERINFEC, Instituto de Salud Carlos III, Madrid, Spain; Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Rodríguez-Gascón A; Pharmacokinetic, Nanotechnology, and Gene Therapy Group (PharmaNanoGene), Faculty of Pharmacy, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain; Bioaraba, Microbiology, Infectious Disease, Antimicrobial Agents, and Gene Therapy Group, Vitoria-Gasteiz, Spain., Canut A; Bioaraba, Microbiology, Infectious Disease, Antimicrobial Agents, and Gene Therapy Group, Vitoria-Gasteiz, Spain; Microbiology Service, Araba University Hospital, Osakidetza Basque Health Service, Vitoria-Gasteiz, Spain., García-Patos V; Dermatology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Farré M; Clinical Pharmacology Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain., Marks M; Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK; Hospital for Tropical Diseases, London, UK; Division of Infection and Immunity, University College London, London, UK., Giacani L; Department of Medicine, Division of Allergy and Infectious Diseases and Department of Global Health, University of Washington, Seattle, WA, USA., Vall-Mayans M; Skin Neglected Tropical Diseases and Sexually Transmitted Infections Section, Hospital Universitari Germans Trias i Pujol, Badalona, Spain., Mitjà O; Skin Neglected Tropical Diseases and Sexually Transmitted Infections Section, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; Fundació Lluita Contra les Infeccions, Hospital Universitari Germans Trias i Pujol, Badalona, Spain. Electronic address: omitja@lluita.org.

Publikováno v: The Lancet. Infectious diseases [Lancet Infect Dis] 2024 Apr; Vol. 24 (4), pp. 404-416. Date of Electronic Publication: 2024 Jan 08.

Bilateral buttock eosinophilic cellulitis after intramuscular benzathine penicillin injection.

Autor: Borba MGS; Fundação de Medicina Tropical Dr Heitor Vieira Dourado (FMT-HVD), Manaus, Brazil., Baía-da-Silva DC; Fundação de Medicina Tropical Dr Heitor Vieira Dourado (FMT-HVD), Manaus, Brazil.; Universidade do Estado do Amazonas (UEA), Manaus, Brazil.; Instituto Leônidas & Maria Deane-Fiocruz Amazônia (Fiocruz), Manaus, Brazil.; Universidade Nilton Lins, Manaus, Brazil., Fabricio D; Fundação de Medicina Tropical Dr Heitor Vieira Dourado (FMT-HVD), Manaus, Brazil., Almeida G; Fundação de Medicina Tropical Dr Heitor Vieira Dourado (FMT-HVD), Manaus, Brazil., Dos Reis MF; Fundação Centro de Controle de Oncologia do Amazonas (FCECON), Manaus, Brazil.; Universidade Federal do Amazonas (UFAM), Manaus, Brazil.; Centro Universitário FAMETRO, Manaus, Brazil., Mendes L; Fundação de Medicina Tropical Dr Heitor Vieira Dourado (FMT-HVD), Manaus, Brazil.; Universidade Federal do Amazonas (UFAM), Manaus, Brazil., Lacerda MVG; Fundação de Medicina Tropical Dr Heitor Vieira Dourado (FMT-HVD), Manaus, Brazil.; Instituto Leônidas & Maria Deane-Fiocruz Amazônia (Fiocruz), Manaus, Brazil., Safe IP; Fundação de Medicina Tropical Dr Heitor Vieira Dourado (FMT-HVD), Manaus, Brazil.; Universidade do Estado do Amazonas (UEA), Manaus, Brazil.; Centro Universitário FAMETRO, Manaus, Brazil.

Publikováno v: International journal of dermatology [Int J Dermatol] 2024 Jan; Vol. 63 (1), pp. 85-87. Date of Electronic Publication: 2023 Oct 17.

Intramuscular versus enteral penicillin prophylaxis to prevent progression of rheumatic heart disease: Study protocol for a noninferiority randomized trial (the GOALIE trial).

Autor: Rwebembera J; Division of Adult Cardiology, Department of Adult Cardiology, Uganda Heart Institute, Kampala, Uganda. Electronic address: joselynr36@gmail.com., Ndagire E; Division of Paediatric Cardiology, Department of Paediatric Cardiology, Uganda Heart Institute, Kampala, Uganda., Carvalho N; Economics of Global Health and Infectious Diseases Unit, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia., Webel AR; Department of Child, Family and Population Health Nursing, University of Washington, Seattle, Washington., Sable C; Division of Cardiology, Children's National Hospital, Washington, DC., Okello E; Division of Adult Cardiology, Department of Adult Cardiology, Uganda Heart Institute, Kampala, Uganda., Sarnacki R; Global Cardiology Research Initiative, Children's National Hospital, Washington, DC., Spaziani AM; Global Cardiology Research Initiative, Children's National Hospital, Washington, DC., Mucunguzi A; Department of Finance and Administration, Rheumatic Heart Disease Research Collaborative in Uganda, Uganda Heart Institute, Kampala, Uganda., Engelman D; Tropical Diseases Research Group, Murdoch Children's Research Institute, Melbourne, Australia; Melbourne Children's Global Health Initiative, Royal Children's Hospital, Melbourne, Australia; Department of Paediatrics, University of Melbourne, Melbourne, Australia., Grobler A; Department of Paediatrics, University of Melbourne, Melbourne, Australia; Clinical Epidemiology and Biostatistics Unit, Murdoch Children's Research Institute, Melbourne, Australia., Steer A; Tropical Diseases Research Group, Murdoch Children's Research Institute, Melbourne, Australia; Melbourne Children's Global Health Initiative, Royal Children's Hospital, Melbourne, Australia; Department of Paediatrics, University of Melbourne, Melbourne, Australia., Beaton A; Department of Paediatrics, School of Medicine, University of Cincinnati, Cincinnati, OH; Division of Cardiology, The Heart Institute, Cincinnati Children's Medical Center, Cincinnati, OH.

Publikováno v: American heart journal [Am Heart J] 2024 Sep; Vol. 275, pp. 74-85. Date of Electronic Publication: 2024 May 24.