New Host-Directed Therapeutics for the Treatment of Clostridioides difficile Infection.

Autor: Andersson JA; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA.; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas, USA., Peniche AG; Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA., Galindo CL; Department of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USA., Boonma P; Faculty of Medicine, King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand., Sha J; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.; Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, Texas, USA., Luna RA; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA.; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas, USA., Savidge TC; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA.; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, Texas, USA., Chopra AK; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA achopra@utmb.edu smdann@utmb.edu.; Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, Texas, USA.; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, Texas, USA., Dann SM; Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA achopra@utmb.edu smdann@utmb.edu.; Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, Texas, USA.; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, Texas, USA.

Publikováno v: MBio [mBio] 2020 Mar 10; Vol. 11 (2). Date of Electronic Publication: 2020 Mar 10.

Aging impairs protective host defenses against Clostridioides (Clostridium) difficile infection in mice by suppressing neutrophil and IL-22 mediated immunity.

Autor: Peniche AG; Department of Internal Medicine, Galveston, TX, USA; Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA., Spinler JK; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, TX, USA., Boonma P; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, TX, USA., Savidge TC; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA; Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, TX, USA., Dann SM; Department of Internal Medicine, Galveston, TX, USA; Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA. Electronic address: smdann@utmb.edu.

Publikováno v: Anaerobe [Anaerobe] 2018 Dec; Vol. 54, pp. 83-91. Date of Electronic Publication: 2018 Aug 09.

New Role for FDA-Approved Drugs in Combating Antibiotic-Resistant Bacteria.

Autor: Andersson JA; Institute for Translational Sciences, University of Texas Medical Branch (UTMB), Galveston, Texas, USA., Fitts EC; Department of Microbiology and Immunology, UTMB, Galveston, Texas, USA., Kirtley ML; Department of Microbiology and Immunology, UTMB, Galveston, Texas, USA., Ponnusamy D; Department of Microbiology and Immunology, UTMB, Galveston, Texas, USA., Peniche AG; Department of Internal Medicine, UTMB, Galveston, Texas, USA., Dann SM; Department of Internal Medicine, UTMB, Galveston, Texas, USA Institute for Human Infections and Immunity, UTMB, Galveston, Texas, USA., Motin VL; Department of Microbiology and Immunology, UTMB, Galveston, Texas, USA Institute for Human Infections and Immunity, UTMB, Galveston, Texas, USA Department of Pathology, UTMB, Galveston, Texas, USA WHO Collaborating Center for Vaccine Development, UTMB, Galveston, Texas, USA Center for Biodefense and Emerging Infectious Diseases, UTMB, Galveston, Texas, USA., Chauhan S; Institute for Translational Sciences, University of Texas Medical Branch (UTMB), Galveston, Texas, USA., Rosenzweig JA; Department of Biology, Texas Southern University, Houston, Texas, USA., Sha J; Department of Microbiology and Immunology, UTMB, Galveston, Texas, USA Institute for Human Infections and Immunity, UTMB, Galveston, Texas, USA., Chopra AK; Institute for Translational Sciences, University of Texas Medical Branch (UTMB), Galveston, Texas, USA Department of Microbiology and Immunology, UTMB, Galveston, Texas, USA Institute for Human Infections and Immunity, UTMB, Galveston, Texas, USA WHO Collaborating Center for Vaccine Development, UTMB, Galveston, Texas, USA Center for Biodefense and Emerging Infectious Diseases, UTMB, Galveston, Texas, USA achopra@utmb.edu.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2016 May 23; Vol. 60 (6), pp. 3717-29. Date of Electronic Publication: 2016 May 23 (Print Publication: 2016).

Antileishmanial Activity of Disulfiram and Thiuram Disulfide Analogs in an Ex Vivo Model System Is Selectively Enhanced by the Addition of Divalent Metal Ions.

Autor: Peniche AG; Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA Escuela de Ciencias Básicas, Facultad de Salud, Universidad del Valle, Cali, Colombia., Renslo AR; Small Molecule Discovery Center, Center for Discovery and Innovation in Parasitic Diseases, and Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, California, USA., Melby PC; Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA Center for Tropical Diseases, University of Texas Medical Branch, Galveston, Texas, USA., Travi BL; Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA Center for Tropical Diseases, University of Texas Medical Branch, Galveston, Texas, USA brltravi@utmb.edu.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2015 Oct; Vol. 59 (10), pp. 6463-70. Date of Electronic Publication: 2015 Aug 03.

Recent insights into Clostridium difficile pathogenesis.

Autor: Peniche AG; Infectious Disease Division, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas 77555-0435, USA., Savidge TC, Dann SM

Publikováno v: Current opinion in infectious diseases [Curr Opin Infect Dis] 2013 Oct; Vol. 26 (5), pp. 447-53.