Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Pengyi Zhao"'
Autor:
Theresa Gewering, Deepali Waghray, Kristian Parey, Hendrik Jung, Nghi NB Tran, Joel Zapata, Pengyi Zhao, Hao Chen, Dovile Januliene, Gerhard Hummer, Ina Urbatsch, Arne Moeller, Qinghai Zhang
Publikováno v:
eLife, Vol 12 (2024)
P-glycoprotein (Pgp) is a prototypical ATP-binding cassette (ABC) transporter of great biological and clinical significance.Pgp confers cancer multidrug resistance and mediates the bioavailability and pharmacokinetics of many drugs (Juliano and Ling,
Externí odkaz:
https://doaj.org/article/7fa28e67501440539767d8acba59a675
Autor:
Gewering, Theresa, Waghray, Deepali, Parey, Kristian, Jung, Hendrik, Tran, Nghi N. B., Zapata, Joel, Pengyi Zhao, Hao Chen, Januliene, Dovile, Hummer, Gerhard, Urbatsch, Ina, Moeller, Arne, Qinghai Zhang
Publikováno v:
eLife; 1/23/2024, p1-21, 21p
Autor:
Teng Yuan, Jin Wang, Chuan Shan, Nicholas Hadler, Qi Tang, Xiaohan Ye, Hao Chen, Lukasz Wojtas, Xiaodong Shi, Pengyi Zhao
Publikováno v:
J Am Chem Soc
Here we report the first example of alkyne trifunctionalization through simultaneous construction of C-C, C-O, and C-N bonds via gold catalysis. With the assistance of a γ-keto directing group, sequential gold-catalyzed alkyne hydration, vinyl-gold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2133a73bf99790288e051f4777f8af7
https://doi.org/10.1021/jacs.1c01811
https://doi.org/10.1021/jacs.1c01811
Publikováno v:
Anal Chem
Recently microdroplet reactions have aroused much interest because the microdroplet provides a unique medium where organic reactions could be accelerated by a factor of 10(3) or more. However, microdroplet reactions of proteins have been rarely studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e69ac116c44a79685f22c171bd0f73f
https://doi.org/10.1021/acs.analchem.0c04974
https://doi.org/10.1021/acs.analchem.0c04974
Autor:
Theresa Gewering, Deepali Waghray, Kristian Parey, Joel Zapata, Pengyi Zhao, Hao Chen, Dovile Januliene, Ina L. Urbatsch, Arne Moeller, Qinghai Zhang
P-glycoprotein (Pgp) is a highly dynamic ATP-binding cassette transporter that confers cancer multidrug resistance and mediates the bioavailability and pharmacokinetics of many drugs. Structural and biochemical data have provided insights into the bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbec6cb1a2dc6e68b194a628ed141d6e
https://doi.org/10.1101/2022.04.28.489897
https://doi.org/10.1101/2022.04.28.489897
Autor:
Matrika Bhattarai, Hao Chen, Pengyi Zhao, Qi Wang, Michael A. Held, Tariq Alnsour, Ahmed Faik
Publikováno v:
J Am Soc Mass Spectrom
Conventional mass spectrometry (MS)-based analytical methods for small carbohydrate fragments (oligosaccharides, degree of polymerization 2–12) are time-consuming due to the need for offline sample pretreatment such as desalting. Herein, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba51ed5239a3e3b7d3dc5984232c7f0e
https://doi.org/10.1021/jasms.0c00310
https://doi.org/10.1021/jasms.0c00310
Autor:
Jonathan Jean, Xiaohan Ye, Shun Teng, Xiaodong Shi, Pengyi Zhao, Yaping Yi, Chuan Shan, Hao Chen, Lukasz Wojtas, Jin Wang, Teng Yuan
Publikováno v:
Chem. 6:1420-1431
Summary A synergistic gold-iron (Au-Fe) catalytic system was developed for sequential alkyne hydration and vinyl Au addition to aldehydes or ketones. Fe(acac)3 was identified as an essential co-catalyst in preventing vinyl Au protodeauration and faci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59f79357a44dc2b330c6b9f7698a912c
https://doi.org/10.1016/j.chempr.2020.03.014
https://doi.org/10.1016/j.chempr.2020.03.014
Facilitating Gold Redox Catalysis with Electrochemistry: An Efficient Chemical‐Oxidant‐Free Approach
Autor:
Xiaodong Shi, Hao Guo, Yanbin Zhang, Hao Chen, Lukasz Wojtas, Shuyao Zhang, Pengyi Zhao, Qilin Wang, Chuan Shan, Xiaohan Ye
Publikováno v:
Angew Chem Int Ed Engl
Due to the high oxidation potential between Au(I) and Au(III), gold redox catalysis requires at least stoichiometric amounts of a strong oxidant. We herein report the first example of an electrochemical approach in promoting gold-catalyzed oxidative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b30ed9675deeed62bd5d7a64ef1f796
https://doi.org/10.1002/ange.201909082
https://doi.org/10.1002/ange.201909082
Publikováno v:
International Journal of Mass Spectrometry. 443:41-45
We recently reported a new quantitation method using mass spectrometry (MS) in combination with electrochemistry (EC, J. Am. Soc. Mass Spectrom., 2019, 30, 685). The strength of this method is that no reference standard or isotope-labeled compound is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b543f76ab2a8cff1be5a0e0bc1593185
https://doi.org/10.1016/j.ijms.2019.05.017
https://doi.org/10.1016/j.ijms.2019.05.017
Publikováno v:
Journal of the American Society for Mass Spectrometry. 30:685-693
Mass spectrometry-based quantification method has advanced rapidly. In general, the methods for accurate quantification rely on the use of authentic target compounds or isotope-labeled compounds as standards, which might be not available or difficult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c9ecbf3ec8c2ee0cc6bde7337e0a89a
https://doi.org/10.1007/s13361-018-2116-6
https://doi.org/10.1007/s13361-018-2116-6