Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Pengyan Xia"'
Autor:
Jialin Xia, Hong Chen, Xiaoxiao Wang, Weixuan Chen, Jun Lin, Feng Xu, Qixing Nie, Chuan Ye, Bitao Zhong, Min Zhao, Chuyu Yun, Guangyi Zeng, Yuejian Mao, Yongping Wen, Xuguang Zhang, Sen Yan, Xuemei Wang, Lulu Sun, Feng Liu, Chao Zhong, Pengyan Xia, Changtao Jiang, Huiying Rao, Yanli Pang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Non-alcoholic steatohepatitis (NASH) is a severe type of the non-alcoholic fatty liver disease (NAFLD). NASH is a growing global health concern due to its increasing morbidity, lack of well-defined biomarkers and lack of clinically effective
Externí odkaz:
https://doaj.org/article/f8e4546b18a54e5b9dbb16a3dd39f244
Autor:
Jiawan Wang, Hao Zhang, Hailong Yuan, Siqi Chen, Ying Yu, Xuan Zhang, Zeyu Gao, Heng Du, Weitao Li, Yaohui Wang, Pengyan Xia, Jun Wang, Moshi Song
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract The gut microbiome has emerged as a potential target for the treatment of cardiovascular disease. Ischemia/reperfusion (I/R) after myocardial infarction is a serious complication and whether certain gut bacteria can serve as a treatment opti
Externí odkaz:
https://doaj.org/article/78b82f95e6f445bdaac11c2cdf2bd508
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The developmental process of group 2 innate lymphoid cells (ILC2) involves migration between different internal organs. Here the authors show that ILC2s migrate from the lung to the intestine to undergo maturation after treatment with IL-33 and that
Externí odkaz:
https://doaj.org/article/1fb55dbe9c3e4434ab8fee8678bb9192
Autor:
Lijun Zhang, Guo Li, Shuhui Tao, Pengyan Xia, Naveed Chaudhry, Shawn Kaura, Sara Saymuah Stone, Meiyan Liu
Publikováno v:
Mediators of Inflammation, Vol 2022 (2022)
Background. Cardiac and brain inflammation can lead to a host of deleterious health effects. Our formal experimental research showed that Ginkgo Biloba Extract (GBE) contributed to the reduction of inflammation in mice with myocardial infarction alon
Externí odkaz:
https://doaj.org/article/da0a6c6d2689427bb19cd844b4a2bc89
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the coronavirus disease 2019 (COVID-19) pandemic, represents a global crisis. Most patients developed mild/moderate symptoms, and the status of immune system
Externí odkaz:
https://doaj.org/article/3633f7a12d9a4781b7ee531b89b35520
Autor:
Buqing Ye, Benyu Liu, Lu Hao, Xiaoxiao Zhu, Liuliu Yang, Shuo Wang, Pengyan Xia, Ying Du, Shu Meng, Guanling Huang, Xiwen Qin, Yanying Wang, Xinlong Yan, Chong Li, Junfeng Hao, Pingping Zhu, Luyun He, Yong Tian, Zusen Fan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Embryonic stem cell pluripotency depends upon precise regulation by a core transcription network. Here the authors show that polyglutamylation mediated stabilization of the transcription factor Klf4 by TTLL1 and TTLL4 promotes reprogramming, pluripot
Externí odkaz:
https://doaj.org/article/73012c1b32144569b6f62721f4a3512b
Autor:
Buqing Ye, Benyu Liu, Liuliu Yang, Guanling Huang, Lu Hao, Pengyan Xia, Shuo Wang, Ying Du, Xiwen Qin, Pingping Zhu, Jiayi Wu, Nobuo Sakaguchi, Junyan Zhang, Zusen Fan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Haematopoiesis and the generation of lymphoid cell subsets are controlled by delicate genetic programs enforced via epigenetic regulation. Here the authors show that Pcid2 interacts with ZNHIT1, a component of the SRCAP chromatin remodelling complex,
Externí odkaz:
https://doaj.org/article/99b4f3c177f8426eb90c65ef0672f322
Autor:
Pengyan Xia, Jing Liu, Shuo Wang, Buqing Ye, Ying Du, Zhen Xiong, Ze-Guang Han, Liang Tong, Zusen Fan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Innate lymphoid cells (ILC) are thought to direct immune responses, but little is known about the development and maintenance of ILC subsets. Here the authors show that WASH maintains the pool of NKp46+ ILC3s by recruiting Arid1a to the aryl hydrocar
Externí odkaz:
https://doaj.org/article/82ad5b38f43c48979a1f9a1fb0f01cd2
Publikováno v:
Protein & Cell, Vol 7, Iss 11, Pp 777-791 (2016)
Abstract The host takes use of pattern recognition receptors (PRRs) to defend against pathogen invasion or cellular damage. Among microorganism-associated molecular patterns detected by host PRRs, nucleic acids derived from bacteria or viruses are ti
Externí odkaz:
https://doaj.org/article/08e64bcfa6514b819f3e4423a0825201
Autor:
Shuo Wang, Pengyan Xia, Guanling Huang, Pingping Zhu, Jing Liu, Buqing Ye, Ying Du, Zusen Fan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Natural killer cells are a major component of the innate immune response. Here, Wang et al. show that natural killer cell development requires robust activation of autophagy at the immature stage where it acts to remove damaged mitochondria and reduc
Externí odkaz:
https://doaj.org/article/c697bebcc1d3445d9375a769a48af964