Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Pengxun Han"'
Autor:
Yuchun Cai, Hongyue Zhan, Wenci Weng, Yao Wang, Pengxun Han, Xuewen Yu, Mumin Shao, Huili Sun
Publikováno v:
Skeletal Muscle, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Background Diabetes-related muscle wasting is one of the devastating complications of diabetes, which is associated with muscle autophagy due to insulin-mediated glucose starvation. However, treatment for diabetes-related muscle wasting is l
Externí odkaz:
https://doaj.org/article/4e36774dbb09444b96c867bbfaa9cf89
Autor:
Pengxun Han, Yuchun Cai, Yao Wang, Wenci Weng, Yinghui Chen, Menghua Wang, Hongyue Zhan, Xuewen Yu, Taifen Wang, Mumin Shao, Huili Sun
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The kidney is a high-energy demand organ rich in mitochondria especially renal tubular cells. Emerging evidence suggests that mitochondrial dysfunction, redox imbalance and kidney injury are interconnected. Artemether has biological effects
Externí odkaz:
https://doaj.org/article/dbc88c2de4a048b7bc51329955172b69
Autor:
Gaofeng Song, Pengxun Han, Huili Sun, Mumin Shao, Xuewen Yu, Wenjing Wang, Dongtao Wang, Wuyong Yi, Na Ge, Shunmin Li, Tiegang Yi
Publikováno v:
Journal of International Medical Research, Vol 46 (2018)
Objective The aim of this study was to investigate the renoprotective effects and molecular mechanisms of astragaloside IV (AS-IV) in streptozotocin (STZ)-induced diabetic mice. Methods Male C57BL/6 mice were injected intraperitoneally with STZ at 20
Externí odkaz:
https://doaj.org/article/cc5b074ef3da428b961ec20df3b85bb2
Autor:
Xinhui Liu, Wenjing Wang, Gaofeng Song, Xian Wei, Youjia Zeng, Pengxun Han, Dongtao Wang, Mumin Shao, Juan Wu, Huili Sun, Guoliang Xiong, Shunmin Li
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182558 (2017)
The aim of this study was to investigate the effect and possible mechanism of Astragaloside IV (AS-IV) on retarding the progression of diabetic nephropathy (DN) in a type 2 diabetic animal model, db/db mice. Eight-week-old male db/db diabetic mice an
Externí odkaz:
https://doaj.org/article/983f01e4f3bc4770b1f81ec180c3ed50
Autor:
Pengxun Han, Huili Sun, Yuanzhao Xu, Youjia Zeng, Wuyong Yi, Jia Wu, Mumin Shao, Shunmin Li, Tiegang Yi
Publikováno v:
Kidney & Blood Pressure Research, Vol 37, Iss 4-5, Pp 295-304 (2013)
Aims: To investigate the potential role of renalase in adriamycin nephropathy and the effect of lisinopril on the regulation of renalase. Methods: Adriamycin nephropathy was induced in male Wistar rats (n=12) by a single injection of adriamycin at 2
Externí odkaz:
https://doaj.org/article/0a2af9b89b6649fd81824c2e75d35a95
Autor:
Guangli Rong, Wenci Weng, Jingting Huang, Yijun Chen, Xuewen Yu, Rui Yuan, Xiufen Gu, Xia Wu, Yuchun Cai, Pengxun Han, Mumin Shao, Huili Sun, Na Ge
Publikováno v:
BioMed Research International.
Diabetes is a worldwide metabolic disease with rapid growing incidence, characterized by hyperglycemia. Diabetic kidney disease (DKD), the leading cause of chronic kidney disease (CKD), has a high morbidity according to the constantly increasing diab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c593b3d3dc5e50ea890209151701e21
Autor:
Xinyuan, Cheng, Peng, Zhou, Wenci, Weng, Zhijian, Sun, Honghong, Liu, Yinghui, Chen, Yuchun, Cai, Xuewen, Yu, Taifen, Wang, Mumin, Shao, Wuyong, Yi, Tiegang, Yi, Huili, Sun, Pengxun, Han
Publikováno v:
Am J Transl Res
Chronic kidney disease (CKD) is complex and current treatment remains limited. As we know, glomerular injury plays a dominant role in kidney disease progression. However, accumulating evidence demonstrated that renal tubules, rather than being victim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f08a645c0fb1c90b7ccd922074a4eb3
https://pubmed.ncbi.nlm.nih.gov/35422916
https://pubmed.ncbi.nlm.nih.gov/35422916
Autor:
Wenci Weng, Honghong Liu, Zhijian Sun, Peng Zhou, Xuewen Yu, Mumin Shao, Pengxun Han, Huili Sun
Publikováno v:
Experimental and therapeutic medicine. 23(3)
Type 1 diabetes (T1D) is characterized by dysregulated blood glucose and liver metabolism. In previous studies, niclosamide ethanolamine salt (NEN) and artemether (Art) displayed significant hypoglycemic effects. However, their combined therapeutic e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e774fd08b3e3ca1d90340455acd73741
https://pubmed.ncbi.nlm.nih.gov/35222716
https://pubmed.ncbi.nlm.nih.gov/35222716
Autor:
Yijun, Chen, Wenci, Weng, Haiyang, Zhang, Guangli, Rong, Xuewen, Yu, Qing, Wei, Mumin, Shao, Yuchun, Cai, Pengxun, Han, Huili, Sun
Publikováno v:
Am J Transl Res
Previous studies have demonstrated that both artemether and enalapril are effective in treating diabetic nephropathy (DN). However, the effects and underlying mechanisms of their combination in treating DN remain unknown. The experimental DN model wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d54c299b7e432f3e3b13768e87f0c247
https://pubmed.ncbi.nlm.nih.gov/35173839
https://pubmed.ncbi.nlm.nih.gov/35173839
Autor:
Yao Wang, Wenci Weng, Hongyue Zhan, Mumin Shao, Huili Sun, Xuewen Yu, Pengxun Han, Yuchun Cai
Publikováno v:
Skeletal Muscle
Skeletal Muscle, Vol 11, Iss 1, Pp 1-10 (2021)
Skeletal Muscle, Vol 11, Iss 1, Pp 1-10 (2021)
Background Diabetes-related muscle wasting is one of the devastating complications of diabetes, which is associated with muscle autophagy due to insulin-mediated glucose starvation. However, treatment for diabetes-related muscle wasting is limited. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63b8d5b1a00e33e67afcc7989dc1ec1
http://europepmc.org/articles/PMC8188694
http://europepmc.org/articles/PMC8188694