Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Pengxin Qiu"'
Autor:
Jialuo Mai, Jiayu Gu, Ying Liu, Xincheng Liu, Ke Sai, Zhijie Chen, Wanjun Lu, Xiaozhi Yang, Jingyi Wang, Cui Guo, Shuxin Sun, Fan Xing, Longxiang Sheng, Bingzheng Lu, Zhu Zhu, Hongjiaqi Sun, Dongdong Xue, Yuan Lin, Jing Cai, Yaqian Tan, Chuntao Li, Wei Yin, Lin Cao, Ying Ou‐yang, Pengxin Qiu, Xingwen Su, Guangmei Yan, Jiankai Liang, Wenbo Zhu
Publikováno v:
Molecular Oncology, Vol 13, Iss 7, Pp 1589-1604 (2019)
Activation of the cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathway induces glial differentiation of glioblastoma (GBM) cells, but the mechanism by which microRNA (miRNA) regulate this process remains poorly understood. In this study
Externí odkaz:
https://doaj.org/article/d7ddbd73683b41da8f7ee1aaf43eb0cc
Autor:
Xiao Xiao, Jiankai Liang, Chunlong Huang, Kai Li, Fan Xing, Wenbo Zhu, Ziqing Lin, Wencang Xu, Guangen Wu, Jifu Zhang, Xi Lin, Yaqian Tan, Jing Cai, Jun Hu, Xueqin Chen, Youwei Huang, Zixi Qin, Pengxin Qiu, Xingwen Su, Lijun Chen, Yuan Lin, Haipeng Zhang, Guangmei Yan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Oncolytic virotherapy is a promising strategy for cancer treatment. In this study, the authors demonstrate that DNA-dependent protein kinase (DNA-PK) inhibition sensitizes cancer cells to M1 virus and improves therapeutic effects in refractory cancer
Externí odkaz:
https://doaj.org/article/dbf1917a6c734ba89788a062a0d2b470
Autor:
Jiankai Liang, Li Guo, Kai Li, Xiao Xiao, Wenbo Zhu, Xiaoke Zheng, Jun Hu, Haipeng Zhang, Jing Cai, Yaya Yu, Yaqian Tan, Chuntao Li, Xincheng Liu, Cheng Hu, Ying Liu, Pengxin Qiu, Xingwen Su, Songmin He, Yuan Lin, Guangmei Yan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Oncolytic viruses selectively kill tumour cells and induce anti-tumour immunity. Here, the AUs demonstrate the anti-viral effect of the mevalonate pathway on oncolytic virus M1 in refractory cancer cells and provide evidence for a combination strateg
Externí odkaz:
https://doaj.org/article/eedd8026eda94f72a09d4f75de768ad5
Autor:
Fan Xing, Yizhao Luan, Jing Cai, Sihan Wu, Jialuo Mai, Jiayu Gu, Haipeng Zhang, Kai Li, Yuan Lin, Xiao Xiao, Jiankai Liang, Yuan Li, Wenli Chen, Yaqian Tan, Longxiang Sheng, Bingzheng Lu, Wanjun Lu, Mingshi Gao, Pengxin Qiu, Xingwen Su, Wei Yin, Jun Hu, Zhongping Chen, Ke Sai, Jing Wang, Furong Chen, Yinsheng Chen, Shida Zhu, Dongbing Liu, Shiyuan Cheng, Zhi Xie, Wenbo Zhu, Guangmei Yan
Publikováno v:
Cell Reports, Vol 18, Iss 2, Pp 468-481 (2017)
Summary: Glioblastoma multiforme (GBM) is among the most aggressive of human cancers. Although differentiation therapy has been proposed as a potential approach to treat GBM, the mechanisms of induced differentiation remain poorly defined. Here, we e
Externí odkaz:
https://doaj.org/article/3968fd8bebf440b692cae7ea5b0da112
Autor:
Fan Xing, Yizhao Luan, Jing Cai, Sihan Wu, Jialuo Mai, Jiayu Gu, Haipeng Zhang, Kai Li, Yuan Lin, Xiao Xiao, Jiankai Liang, Yuan Li, Wenli Chen, Yaqian Tan, Longxiang Sheng, Bingzheng Lu, Wanjun Lu, Mingshi Gao, Pengxin Qiu, Xingwen Su, Wei Yin, Jun Hu, Zhongping Chen, Ke Sai, Jing Wang, Furong Chen, Yinsheng Chen, Shida Zhu, Dongbing Liu, Shiyuan Cheng, Zhi Xie, Wenbo Zhu, Guangmei Yan
Publikováno v:
Cell Reports, Vol 23, Iss 9, Pp 2832-2833 (2018)
Externí odkaz:
https://doaj.org/article/40b43ec9dddd49d687e552cf48854352
Autor:
Yang Liu, Jingyi Tan, Chun-Wa Wong, Jun Hu, Jiayu Zhang, Jing Cai, Xingwen Su, Pengxin Qiu, Yuan Lin, Guangmei Yan, Li Guo, Jiankai Liang, Wenbo Zhu, Deli Song, Jia Dan
Publikováno v:
Human Gene Therapy. 32:158-165
Alphavirus M1 is a promising oncolytic virus for cancer therapy. Here, we constructed a fluorescent reporter virus for real-time visualization and quantification of M1 virus both in vitro and in vivo. The reporter-encoding M1 virus maintained the cha
Autor:
Wenbo, Zhu, Jiankai, Liang, Jingyi, Tan, Li, Guo, Jing, Cai, Jun, Hu, Guangmei, Yan, Yang, Liu, Jiayu, Zhang, Deli, Song, Jia, Dan, Chun-Wa, Wong, Xingwen, Su, Pengxin, Qiu, Yuan, Lin
Publikováno v:
Human gene therapy. 32(3-4)
Alphavirus M1 is a promising oncolytic virus for cancer therapy. Here, we constructed a fluorescent reporter virus for real-time visualization and quantification of M1 virus both
Autor:
Songmin He, Zhang Haipeng, Jing Cai, Wenbo Zhu, Jialuo Mai, Ling Lu, Mingshi Gao, Jun Hu, Li Guo, Kai Li, Yaqian Tan, Wei Yin, Jiayu Gu, Chuntao Li, Yuan Lin, Xiao Xiao, Xiaohong Tan, Xingwen Su, Guangmei Yan, Bingzheng Lu, Gong Shoufang, Pengxin Qiu, Jiankai Liang, Fan Xing
Publikováno v:
Human Gene Therapy. 29:950-961
Oncolytic virotherapy is a novel and intriguing treatment strategy for cancer therapy. However, the clinical potential of oncolytic virus as single agent is limited. M1 virus is a promising oncolytic virus that has been tested in preclinical studies.
Autor:
Yaqian Tan, Li Guo, Yuan Lin, Chuntao Li, Ying Liu, Songmin He, Jing Cai, Xincheng Liu, Zhang Haipeng, Guangmei Yan, Yaya Yu, Xingwen Su, Jiankai Liang, Jun Hu, Xiaoke Zheng, Pengxin Qiu, Wenbo Zhu, Kai Li, Cheng Hu, Xiao Xiao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
Oncolytic virus is an attractive anticancer agent that selectively lyses cancer through targeting cancer cells rather than normal cells. Although M1 virus is effective against several cancer types, certain cancer cells present low sensitivity to it.
Autor:
Liu Qinghua, Jing Ye, Pengxin Qiu, Xiaoming Zhou, Lulu Wang, Jinling Liu, Lipeng Xu, Yajie Zhang
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 95:463-473
Diallyl trisulfide (DATS), a major garlic derivative, inhibits cell proliferation and triggers apoptosis in a variety of cancer cell lines. However, the effects of DATS on hepatic stellate cells (HSCs) remain unknown. The aim of this study was to ana