Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Pengxiang Min"'
Autor:
Qianwen Wang, Chenxiang Qi, Pengxiang Min, Yueyuan Wang, Fengwen Ye, Tianxiang Xia, Yujie Zhang, Jun Du
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Gastric cancer is a common and lethal human malignancy worldwide and cancer cell metastasis is the leading cause of cancer-related mortality. MICAL2, a flavoprotein monooxygenase, is an important regulator of epithelial-to-mesench
Externí odkaz:
https://doaj.org/article/9aef05bc469f49fb8c797e62ad16124f
Publikováno v:
Cellular & Molecular Biology Letters, Vol 24, Iss 1, Pp 1-12 (2019)
Abstract Background Hypoxia, a major condition associated with the tumor microenvironment, stimulates the migration of cancer cells. SOX2 is a powerful transcription factor that shows higher expression in several cancers, however, its role in hypoxia
Externí odkaz:
https://doaj.org/article/c0ad70b790cc436d8fee7e7bc1050409
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Aims and Hypothesis: Cell migration is driven by the reorganization of the actin cytoskeleton. Although MICAL2 is known to mediate the oxidation of actin filaments to regulate F-actin dynamics, relatively few studies have investigated the potential r
Externí odkaz:
https://doaj.org/article/366224aeb3034938957a17c35a90542e
Autor:
Pengxiang Min, Lin Zhang, Yueyuan Wang, Chenxiang Qi, Yixuan Song, Maria Bibi, Yujie Zhang, Yadong Ma, Xuyang Zhao, Minjie Yu, Jun Du
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Objectives: MICAL-L2, a member of the molecules interacting with the CasL (MICAL) family, was reported to be highly expressed in several types of cancers, however, the roles of MICAL-L2 in NSCLC pathogenesis remain to be explored. This study is desig
Externí odkaz:
https://doaj.org/article/305b7bdf094f4c40ba04946e9c29d4ed
Autor:
Xuyang Zhao, Yadong Ma, Jie Cui, Haiyang Zhao, Lei Liu, Yueyuan Wang, Pengxiang Min, Lin Zhang, Yongchang Chen, Jun Du, Yujie Zhang, Luo Gu
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Aims and Hypothesis: This study aims to explore the specific molecular mechanism of folliculin (FLCN)-induced proliferation, migration, and invasion in clear cell renal cell carcinoma (ccRCC) and to investigate the relationship of FLCN and HIF2α. Fo
Externí odkaz:
https://doaj.org/article/2d5a5ed5a8f4490fa80de33744efee83
Autor:
Shuo Zhao, Pengxiang Min, Lei Liu, Lin Zhang, Yujie Zhang, Yueyuan Wang, Xuyang Zhao, Yadong Ma, Hui Xie, Chenchen Zhu, Haonan Jiang, Jun Du, Luo Gu
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Aims and Hypothesis: NEDD9 is highly expressed in gastric cancer and has a significant involvement in its pathogenesis. However, the mechanism behind hypoxia-promoted cancer cell migration and its regulation because of NEDD9 is still unknown. The aim
Externí odkaz:
https://doaj.org/article/91f807ac6b264844a5ddcef89acd8cf8
Autor:
Pengxiang Min1, Yingying Li1, Cuirong Wang1, Junting Fan2, Shangming Liu1, Xiang Chen1, Yamin Tang3, Feng Han1,4, Aixia Zhang5 aixia.zhang@njmu.edu.cn, Lili Feng1 fenghan169@njmu.edu.cn
Publikováno v:
Journal of Biomedical Research. Jul2024, Vol. 38 Issue 4, p322-333. 12p.
Autor:
Tianxiang Xia, Fengwen Ye, Yixing Yang, Pengxiang Min, Chengxiang Qi, Qianwen Wang, Weizhen Zhao, Yueyuan Wang, Yujie Zhang, Jun Du
Molecules interacting with CasL (MICALs) are critical mediators of cell motility that act by cytoskeleton rearrangement. However, the molecular mechanisms underlying the regulation of cancer cell invasion remain elusive. The aim of this study was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b08ceb02428b7d4010c5a9038ace933
https://doi.org/10.21203/rs.3.rs-2939710/v1
https://doi.org/10.21203/rs.3.rs-2939710/v1
Autor:
Jiadong Xia, Qijie Zhang, Jiaochen Luan, Pengxiang Min, Hanjie Zhang, Gang Chen, Chengjian Ji, Ninghong Song
Publikováno v:
Cell cycle (Georgetown, Tex.). 22(1)
Considering the determining role of TGFβ signaling in the tumor microenvironment (TME) on immune evasion, the inhibition of signaling is expected to enhance the therapeutic efficacy of immunotherapies, especially immune checkpoint blockade (ICB), wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b70135438c9d7d5af866f637f20a9b
https://pubmed.ncbi.nlm.nih.gov/35923142
https://pubmed.ncbi.nlm.nih.gov/35923142
Autor:
Lu Lu, Hang Xu, Gang Sheng, Lingtong Meng, Yu Zhang, Lili Feng, Feng Han, Li Zhang, Cuirong Wang, Pengxiang Min, Yijun Wang
Publikováno v:
Nanoscale. 13:4249-4261
Conventional prostate cancer treatment strategies, including chemotherapy and radiotherapy, cannot effectively eradicate prostate cancer, especially castration resistance prostate cancer. Herein, we developed a novel nanotherapy platform that consist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009407c93cdf2f5c4cae235530d7c082
https://doi.org/10.1039/d0nr07196j
https://doi.org/10.1039/d0nr07196j