Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Pengning Xu"'
Autor:
Markus Götz, Anders Barth, Søren S. -R. Bohr, Richard Börner, Jixin Chen, Thorben Cordes, Dorothy A. Erie, Christian Gebhardt, Mélodie C. A. S. Hadzic, George L. Hamilton, Nikos S. Hatzakis, Thorsten Hugel, Lydia Kisley, Don C. Lamb, Carlos de Lannoy, Chelsea Mahn, Dushani Dunukara, Dick de Ridder, Hugo Sanabria, Julia Schimpf, Claus A. M. Seidel, Roland K. O. Sigel, Magnus B. Sletfjerding, Johannes Thomsen, Leonie Vollmar, Simon Wanninger, Keith R. Weninger, Pengning Xu, Sonja Schmid
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/1b1c0a8db83947af9fa8432a08f638ac
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1278 (2024)
Dynamic mutations in some human genes containing trinucleotide repeats are associated with severe neurodegenerative and neuromuscular disorders—known as Trinucleotide (or Triplet) Repeat Expansion Diseases (TREDs)—which arise when the repeat numb
Externí odkaz:
https://doaj.org/article/4512aaf1d9174391b6618094e79e6f79
Autor:
Markus Götz, Anders Barth, Søren S.-R. Bohr, Richard Börner, Jixin Chen, Thorben Cordes, Dorothy A. Erie, Christian Gebhardt, Mélodie C. A. S. Hadzic, George L. Hamilton, Nikos S. Hatzakis, Thorsten Hugel, Lydia Kisley, Don C. Lamb, Carlos de Lannoy, Chelsea Mahn, Dushani Dunukara, Dick de Ridder, Hugo Sanabria, Julia Schimpf, Claus A. M. Seidel, Roland K. O. Sigel, Magnus Berg Sletfjerding, Johannes Thomsen, Leonie Vollmar, Simon Wanninger, Keith R. Weninger, Pengning Xu, Sonja Schmid
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Single-molecule FRET (smFRET) is a versatile technique to study the dynamics and function of biomolecules since it makes nanoscale movements detectable as fluorescence signals. The powerful ability to infer quantitative kinetic information f
Externí odkaz:
https://doaj.org/article/f3d0063840344222b5c71d7c09bdcf04
Autor:
Feng Pan, Yuan Zhang, Pengning Xu, Viet Hoang Man, Christopher Roland, Keith Weninger, Celeste Sagui
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2819-2832 (2021)
Pathogenic DNA secondary structures have been identified as a common and causative factor for expansion in trinucleotide, hexanucleotide, and other simple sequence repeats. These expansions underlie about fifty neurological and neuromuscular disorder
Externí odkaz:
https://doaj.org/article/e304cfe22494421494c94ebc332c8865
Autor:
Pengning Xu, Jiahui Zhang, Feng Pan, Chelsea Mahn, Christopher Roland, Celeste Sagui, Keith Weninger
Publikováno v:
Journal of Molecular Biology. 435:168086
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19f94371ec6733ea4bbc20de12bc5ad0
https://doi.org/10.1016/j.jmb.2023.168086
https://doi.org/10.1016/j.jmb.2023.168086
Autor:
Yuan Zhang, Pengning Xu, Celeste Sagui, Feng Pan, Keith Weninger, Christopher Roland, Viet Hoang Man
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2819-2832 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Pathogenic DNA secondary structures have been identified as a common and causative factor for expansion in trinucleotide, hexanucleotide, and other simple sequence repeats. These expansions underlie about fifty neurological an
Pathogenic DNA secondary structures have been identified as a common and causative factor for expansion in trinucleotide, hexanucleotide, and other simple sequence repeats. These expansions underlie about fifty neurological an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63203fffa3ef36270aa58d6e995d47d3
https://doi.org/10.1016/j.csbj.2021.04.037
https://doi.org/10.1016/j.csbj.2021.04.037
Autor:
M. C. A. S. Hadzic, C. de Lannoy, Don C. Lamb, D. Dunukara, R. K. O. Sigel, George L. Hamilton, Sonja Schmid, Hugo Sanabria, D. A. Erie, Pengning Xu, L. Kisley, J. Schimpf, Johannes Thomsen, Thorsten Hugel, Nikos S. Hatzakis, C. A. M. Seidel, M. Götz, Simon Wanninger, Thorben Cordes, Keith Weninger, C. Mahn, J. Chen, Christian Gebhardt, Anders Barth, Soeren S-R Bohr, L. Vollmar, R. Börner, Magnus Berg Sletfjerding, Dick de Ridder
Publikováno v:
bioRxiv
Single-molecule FRET (smFRET) is a versatile technique to study the dynamics and function of biomolecules since it makes nanoscale movements detectable as fluorescence signals. The powerful ability to infer quantitative kinetic information from smFRE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358d90bf47089b2d927807076bcb8915
https://doi.org/10.1101/2021.11.23.469671
https://doi.org/10.1101/2021.11.23.469671
Autor:
Parminder Kaur, Jacob Piehler, Keith Weninger, Pengyu Hao, Dhruv Bhattaram, Ming Liu, Pengning Xu, Chelsea Mahn, Patricia L. Opresko, Changjiang You, Ryan P. Barnes, Hong Wang, Susan Smith, Robert Riehn, Hai Pan, Qingyu Tang
The shelterin complex consisting of TRF1, TRF2, RAP1, TIN2, TPP1, and POT1, functions to prevent false recognition of telomeres as double-strand DNA breaks, and to regulate telomerase and DNA repair protein access. TIN2 is a core component linking do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18f6cb8df4e3b14d5f52987f69827304
https://doi.org/10.1101/2020.09.12.286559
https://doi.org/10.1101/2020.09.12.286559
Publikováno v:
Nucleic Acids Research
DNA trinucleotide repeats (TRs) can exhibit dynamic expansions by integer numbers of trinucleotides that lead to neurodegenerative disorders. Strand slipped hairpins during DNA replication, repair and/or recombination may contribute to TR expansion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4935e86d1596a4ec03fd60a31090252
https://pubmed.ncbi.nlm.nih.gov/31974547
https://pubmed.ncbi.nlm.nih.gov/31974547
Autor:
Pengning Xu, Keith Weninger
Publikováno v:
Biophysical Journal. 121:209a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e6b5bb4d1206a17cc4d1f924ca3ef94
https://doi.org/10.1016/j.bpj.2021.11.1666
https://doi.org/10.1016/j.bpj.2021.11.1666