Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Pengkai Wu"'
Autor:
Xiaowei Han, Guozheng Zhang, Xiaozhen Wu, Shufeng Xu, Jiahuan Liu, Kaikai Wang, Tianqing Liu, Pengkai Wu
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Immune checkpoint inhibitor (ICI)-derived evolution offers a versatile means of developing novel immunotherapies that targets programmed death-ligand 1 (PD-L1)/programmed death-1 (PD-1) axis. However, one major challenge is T cell exhaustion
Externí odkaz:
https://doaj.org/article/51edaafe90ee4cbabcc02350e8b2ed1d
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background RBC membrane derived nanoparticles (NPs) represent an emerging platform with prolonged circulation capacity for the delivery of active substances. For functionalize derived RBCs NPs, various strategies, such as biomimetic rebuildi
Externí odkaz:
https://doaj.org/article/89ea126e25854d4e8520c2898678a8dd
Autor:
Pengkai Wu, Haitian Zhang, Yin Yin, Meiling Sun, Shuai Mao, Huihui Chen, Yexuan Deng, Shuai Chen, Shuo Li, Beicheng Sun
Publikováno v:
Advanced Science, Vol 9, Iss 15, Pp n/a-n/a (2022)
Abstract Nano‐based immunotherapy of therapeutic biomolecules is attractive but tremendously hampered by the poor delivery efficiency. This study reports a novel delivery system of fluorinated‐coordinative‐epigallocatechin gallate (EGCG), refer
Externí odkaz:
https://doaj.org/article/e6fce42768d549d88e0f99001ffb0262
Publikováno v:
Journal of Traditional Chinese Medical Sciences, Vol 2, Iss 1, Pp 32-38 (2015)
Background: Current methods of extending the storage time of wild Cordyceps sinensis adversely affect the nutritive and medicinal value of the product. Thus, this study was designed to investigate the effects of heat treatment, a relatively safe stor
Externí odkaz:
https://doaj.org/article/03d14c780d4745a2b3d73a50d311dc34
Publikováno v:
ACS Nano. 17:7498-7510
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9627ab3715b76e4d06c59ed05182d686
https://doi.org/10.1021/acsnano.2c12600
https://doi.org/10.1021/acsnano.2c12600
Autor:
Pengkai Wu, Haitian Zhang, Meiling Sun, Shuai Mao, Qifeng He, Yuze Shi, Yexuan Deng, Zhongjun Dong, Qingxiang Xu, Chen Zhao, Wenjie Zhang, Beicheng Sun
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 34(38)
Chemoimmunotherapy has shown great potential to activate an immune response, but the immunosuppressive microenvironment associated with T cell exhaustion remains a challenge in cancer therapy. The proper immune-modulatory strategy to provoke a robust
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb7d5d4cbacd98c7061c79f59957b2b
https://pubmed.ncbi.nlm.nih.gov/35918816
https://pubmed.ncbi.nlm.nih.gov/35918816
Publikováno v:
Science China Materials. 64:241-251
Incorporating functional ligands and biodegradable bonds into biocompatible low-molecular-weight (LMW) polymers, such as 1.8 kDa poly(ethylenimine) (PEI 1.8k), is a common strategy to improve the properties of LMW polymers including biosafety and del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e09b6da4dda064626709964e5ce4c1d8
https://doi.org/10.1007/s40843-020-1366-2
https://doi.org/10.1007/s40843-020-1366-2
Publikováno v:
Bioconjugate Chemistry. 31:698-707
Polyethylenimine (PEI) is a promising delivery vector of nucleic acids, but cytotoxicity and only moderate transfection efficacy with small RNAs limit its applications. Here we hypothesized that hydrophobization of PEI by combined modification with p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1620582ca3262d60e334c10e2596851
https://doi.org/10.1021/acs.bioconjchem.9b00834
https://doi.org/10.1021/acs.bioconjchem.9b00834
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-13 (2021)
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-13 (2021)
Background RBC membrane derived nanoparticles (NPs) represent an emerging platform with prolonged circulation capacity for the delivery of active substances. For functionalize derived RBCs NPs, various strategies, such as biomimetic rebuilding of RBC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad343a9cf66f4e966f71c89bf36e577
https://doi.org/10.1186/s12951-021-00949-7
https://doi.org/10.1186/s12951-021-00949-7
Publikováno v:
Biomaterials. 284:121492
Hepatic stellate cell (HSC)-targeted delivery is an attractive strategy for liver fibrosis therapy, but the efficacy is hampered by poor delivery of nanomaterials and complicated microenvironments of the fibrotic liver. Here, we report a versatile CX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81738b482ffefb0785a1a5e6af25829
https://doi.org/10.1016/j.biomaterials.2022.121492
https://doi.org/10.1016/j.biomaterials.2022.121492