Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Pengguo Chen"'
Autor:
Donglin Liu, Pengguo Chen
Publikováno v:
Animal Models and Experimental Medicine, Vol 7, Iss 3, Pp 362-366 (2024)
Abstract Background Nonalcoholic steatohepatitis (NASH) is characterized by liver steatosis, inflammation, and even fibrosis. NASH is likely to develop into cirrhosis and liver cancer, the major causes of liver related deaths. We aimed to study the e
Externí odkaz:
https://doaj.org/article/6b09ca84fa8b4d449f705dc031477b82
Autor:
Jin Lu, Lili Wan, Yuan Zhong, Qi Yu, Yonglong Han, Pengguo Chen, Beiyun Wang, Wei Li, Ya Miao, Cheng Guo
Publikováno v:
Journal of Pharmacological Sciences, Vol 129, Iss 3, Pp 188-195 (2015)
The therapeutic response rates of patients to donepezil vary from 20% to 60%, one of the reasons is their genetic differences in donepezil-metabolizing enzymes, which directly influence liver metabolism. However, the mechanism of donepezil metabolism
Externí odkaz:
https://doaj.org/article/f14b10a288104cc8a1d4bfae5c2aa3a4
Publikováno v:
PeerJ, Vol 3, p e1518 (2015)
Hepatic stellate cells (HSCs) play a crucial role in liver fibrosis, which is a pathological process characterized by extracellular matrix accumulation. NR4A2 is a nuclear receptor belonging to the NR4A subfamily and vital in regulating cell growth,
Externí odkaz:
https://doaj.org/article/c949d38e8ad74d0a80353f64bcdabb34
The aim of this study was to evaluate the short-term effect of temperature on the risk of acute pancreatitis (AP) in southern China. We performed a time-series study of 2822 patients admitted with a first episode of AP in Nanchang between May 2014 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ca3e158cb9aa21e691e63cf39cd097
Publikováno v:
Oncotarget
Systemic amyloidosis is a rare disease involving multiple organs. It is difficult to establish diagnosis as the symptoms is diverse and non-specific. And without specific therapy the prognosis is very poor. We analyzed detailed clinical and laborator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce71de7e4c9377bdf01410523516a7d0
https://doi.org/10.18632/oncotarget.25055
https://doi.org/10.18632/oncotarget.25055
Publikováno v:
Neuroscience Letters. 614:43-48
Aim Polymorphisms in the apolipoprotein E and CYP2D6 genes are widely reported to be related to Alzheimer's disease. However, few studies have focused on the relationship between polymorphisms in apolipoprotein E and CYP2D6 (rs1065852) genes and ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac58037318ba62bbb9c79926005ea8cb
https://doi.org/10.1016/j.neulet.2015.12.062
https://doi.org/10.1016/j.neulet.2015.12.062
Autor:
Yong-Long Han, Lili Wan, Pengguo Chen, Run Gan, Cheng Guo, Yan Li, Quanjun Yang, Qi Yu, Bin Li
Publikováno v:
Tumor Biology. 35:12415-12425
Inflammatory responses are key contributors to cancer cachexia and foster a complex cascade of biological outcomes. Baicalin is a natural compound derived from Scutellaria baicalensis that possesses anti-inflammatory properties in many diseases; ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6138153bee45392d17a3966f3b5d3d57
https://doi.org/10.1007/s13277-014-2558-9
https://doi.org/10.1007/s13277-014-2558-9
Autor:
Run Gan, Jinlu Huang, Lili Wan, Jin Lu, Jie Li, Quanjun Yang, Cheng Guo, Pengguo Chen, Yan Huo
Publikováno v:
Scientific Reports
Liver fibrosis is a wound-healing response characterized with the accumulation of extracellular matrix (ECM). And hepatic stellate cells (HSCs) are the principal cell source of ECM. NR4A2 (Nurr1) is a member of orphan nuclear receptor NR4A family and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1611a7df97248da9f73b65e8312bfa20
Publikováno v:
Biochemical pharmacology. 92(4)
Nur77 is an orphan nuclear receptor that belongs to the nuclear receptor 4A (NR4A) subfamily, which has been implicated in a variety of biological events, such as cell apoptosis, proliferation, inflammation, and metabolism. Activation of Nur77 has re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f29395144c91730c8cf38ab74232ed
https://pubmed.ncbi.nlm.nih.gov/25316569
https://pubmed.ncbi.nlm.nih.gov/25316569
Publikováno v:
PeerJ
PeerJ, Vol 3, p e1518 (2015)
PeerJ, Vol 3, p e1518 (2015)
Hepatic stellate cells (HSCs) play a crucial role in liver fibrosis, which is a pathological process characterized by extracellular matrix accumulation. NR4A2 is a nuclear receptor belonging to the NR4A subfamily and vital in regulating cell growth,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124fb7bd8a42c8db36e246ff3bde007b
https://doi.org/10.7717/peerj.1518
https://doi.org/10.7717/peerj.1518